Tbc1d2 (NM_198664) Mouse Untagged Clone

CAT#: MC222675

Tbc1d2 (untagged) - Mouse TBC1 domain family, member 2 (Tbc1d2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tbc1d2
• Synonyms: A630005A06Rik; BC022630; Gm1037; PARIS-1; PARIS1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222675 representing NM_198664
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGACGCCCCCGAGCGCACTCCCTCTTCCTCGGAGTCCACACAGCCTCCGGGCTTGGCCAGGGAGC
  CCGAGGTGGTATCTCCCGGGGATTCGGAGGGCTGCGCCCGGCCTCTAGACACGGTCCCTAAGAAACTCTG
  TGGGTATTTAAGTAAGTTTGGCGGCAAAGGACCCATCAAGGGCTGGAAATGCCGCTGGTTCTTCTACGAT
  GAGAGGAAGTGCCACCTGTATTATTCGCGCACCGCGCAGGATGCAAACCCCTTGGACAGCATCGATCTCT
  CCAGTGCGGTCTTTGACTGTAAGGCGGACGCTGAGGAGGAGGGCACTTTTGAAATCAAGACTCCCAGCCG
  GGTTATTACCCTCAAGGCTGCCACCAAGCAGGCCATGCTCTACTGGCTACAGCAGCTGCAGATGAAGCGC
  TGGGAGTTCCACAACAGCCCACCTGCACTTCCCGCCACCCCTGCTGCCGCCCTGGCTGAGAATGGGCCCA
  CCCTGCACCTCAAACTAGAGCAAGAGGAGGCCGAGCTGGAGGAGTTCCTGTGCCCTGTGAAAACACCCAC
  TGGACTCGTGGGTGCGGCAGCTGCCTTACAGCCTGTCCCTGCCGTGCCCTCAGCCCTTCAGAACATCTCC
  CTAAAGCATCTGGGCACTGAAATACAAAACACCATGCACAACATCCGTGGCAACAAGCAGGCCCAAGCGG
  CAGCCCACGGGCCACTCGTGGAAGACTCGCCTCAGGGTGGAGAGCCTCAAAGCGGGGAACAGCCCTCGAT
  CTCTGACCCCAGCCTTCCAGAAAAAGAGCCAGAGGATCCTGCCAAGTCTGCACCCAGGTCCTCTGTGCCC
  TCAGGTCCCACGCAGAAACCCAAGCGGCAAAGCAACACCTTCCCATTCTTTTCCGATGGACTGGCTCGGA
  GCCGCACAGCCCAGGAGAAGGTGGCGGCCTTGGAGCAGCAGGTGCTGATGCTCACCAAAGAGCTCAAGTC
  ACAGAAGGAGCTGGTGATCATCCTACACAAGGCCCTGGAGGCTGCCCAGCAGGAGAAGCGAGCCTCCAGT
  GCCTACCTGGCAGCCACCGAGGACAGAGACCGGTTGGAGCTGGTCCGGCACAAGGTGCGGCAGATCGCTG
  AGCTGAACCAGAGGGTGGAGGCTCTGGAGCAGGGCCGCGAGCGCCTGGCGCATGAGGCCGGCCTGCGGGA
  GCAGCAGGTGCAGGCGCTCCAGCAGCACGTGCAGCTGCTCATGGATAAGAACCATGCCAAGCAACAGGTC
  ATCTGCAAGCTCACCCAGAAGCTCACGGAGGACCTTGCCCAGCCCGCCGACGCTACCAACGGCGACTTCC
  TGAGCCAGCAGGAGAGGATGGAGCATCTGAAGGATGACATGGAAGCATATCGGACCCAGAACCGCTTCCT
  CAACTCTGAGATCCACCAGGTCACCAAGATCTGGAGGAAGGTGGCGGAGAAGGAGAAAGCCCTGCTGACC
  AAGTGCGCCTACCTGCAAGCCAGGAACTGCCAGGTAGAAAGCAAGTACCTGGCCGGGCTTCGGAGGCTGC
  AGGAGGCAGCAGGAGCCGAGGCTGGTGACTTCCCTGAGCTGCTGCAGCAGCTGATCCAGGAGGCCCTGCA
  GTGGGAAGCCGGAGAGGCGGACAGCGTGGGGCTGAGCCCCGTCAGCGAGTACGACGACTATGGCTTCCTG
  ACGGTGCCAGACTACGAGATGGAAGACCTAAAACTGCTAGCCAAGATCCAGGCCTTGGAGGTGCGCTCCC
  ACCACCTGCTGGCCCACGAGGCTGTGGAGAGGCCACTACGGGACCGCTGGGCTACCCTGACGGAGCTCAC
  GCCCTCAGCTGAGCTCAAGCAGCTGCTTCGGGCAGGGGTGCCCCGAGAGCACCGTCCCCGAGTCTGGAGG
  TGGCTGGTCCACCGCCGTGTCAGGCACCTGCAGGCTCCCGGCTGCTACCAAGAGCTTCTAGCCCGGGGCC
  GGGCATGTGAGCATCCTGCGGCTCGTCAGATCGAGCTGGACCTCAACCGGACCTTCCCCACCAACAAGCA
  CTTCACCTGCCCGACCTCCAGTTTCCCTGACAAGCTCCGTCGGGTGCTTCTGGCCTTCTCCTGGCAGAAC
  CCCACCATTGGCTACTGCCAAGGCCTGAACAGGCTGGCGGCCATCGCCCTGTTGGTCCTAGAAGATGAGG
  AGAGTGCCTTCTGGTGCCTGGTGGCCATTGTGGAGACCATACTGCCGGCTGAGTACTACAGCAAGACACT
  GACTGCATCCCAGGTGGACCAGCGGGTGCTCCAGGACCTCCTCTCGGAGAAGCTGCCCCGACTGACTGCG
  CACCTGGGGCAGCACCGTGTAGACCTCTCTCTCATCACTTTCAACTGGTTCCTCGTGGTCTTCGCCGACT
  CTCTCATCAGTGACATCCTCCTGCGGGTCTGGGATGCCTTCCTGTATGAAGGGACCAAGGTGGTGTTCCG
  ATATGCTCTGGCCATCTTCAAGTACAATGAGGAAGCGATCCTGCAACTCCAGGACAGCCTGGAGATCTAC
  CAGTACCTGCGTTTCTTCACCAAGACCATCTGCGACAGCCGGAAGCTCATGAGCATAGCCTTCAATGACA
  TGAACCCATTTCCCATGAAGCAACTGCGGCAGCTGCGGGCAGCCCACCGAGAGCGACTGGAGGCGGAGCT
  GCGCGAGCTAGAGCTGCTGAAAGTGGAGTACTTGCAGAGACGGGCATCCCTGGGCAGAGCACCGCCAGAG
  GGCTGCGTCAGCGAGGACGAAGGAGAAGGCGACAGCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_198664
• Insert Size: 2769 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_198664.3, NP_941066.3
• RefSeq Size: 4305 bp
• RefSeq ORF: 2769 bp
• Locus ID: 381605
• UniProt ID: B1AVH7
• Cytogenetics: 4 B1
• Gene Summary: Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion (By similarity).[UniProtKB/Swiss-Prot Function]