Clca1 (NM_017474) Mouse Untagged Clone

CAT#: MC222584

Clca3 (untagged) - Mouse chloride channel calcium activated 3 (Clca3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Clca1
• Synonyms: Clca2; Clca3; gob-5; gob5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222584 representing NM_017474
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC
  GCCC
  
  ATGGAATCTTTGAAGAGTCCTGTCTTCCTCTTGATCCTCCACCTTCTGGAAGGAGTTCTGAGTGAGTCCC
  TCATCCAACTGAACAACAACGGCTATGAGGGCATCGTCATCGCCATAGACCACGACGTGCCGGAAGATGA
  AGCCCTCATTCAACACATAAAGGACATGGTGACTCAGGCCTCTCCATACCTGTTTGAAGCTACAGGAAAA
  AGATTTTACTTCAAAAATGTTGCCATTTTGATTCCCGAGAGCTGGAAGGCAAAGCCTGAATATACGAGGC
  CAAAACTTGAAACCTTCAAAAACGCTGATGTCCTTGTATCAACAACCAGCCCTCTAGGCAATGATGAGCC
  CTACACCGAACATATAGGAGCATGTGGAGAAAAGGGGATCAGGATTCACCTGACTCCTGACTTCTTAGCA
  GGAAAGAAGCTGACTCAGTATGGGCCACAAGACAGGACCTTTGTCCATGAGTGGGCTCACTTCCGATGGG
  GAGTGTTTAATGAATACAACAACGACGAGAAGTTCTACTTATCCAAAGGAAAACCCCAAGCAGTGAGGTG
  TTCAGCAGCCATTACCGGTAAAAATCAAGTTCGTCGGTGCCAGGGAGGCAGTTGTATCACTAACGGAAAG
  TGTGTAATCGACAGAGTAACGGGACTGTATAAAGACAATTGTGTATTTGTACCAGATCCACACCAAAACG
  AGAAGGCTTCCATCATGTTTAACCAAAATATCAATTCTGTGGTTGAATTCTGTACAGAAAAAAATCACAA
  TCAAGAAGCCCCAAATGACCAAAACCAACGATGCAATCTCCGAAGCACGTGGGAAGTCATCCAGGAATCT
  GAGGACTTCAAGCAAACCACTCCCATGACAGCCCAGCCACCTGCACCCACCTTCTCACTGCTGCAAATTG
  GACAAAGAATTGTGTGCTTAGTTCTTGATAAGTCCGGGAGCATGCTGAACGATGATCGTCTTAACCGAAT
  GAATCAGGCAAGCCGGCTTTTCCTGCTGCAGACTGTGGAGCAGGGATCCTGGGTCGGGATGGTGACCTTT
  GACAGTGCTGCCTATGTACAAAGCGAACTCAAACAGTTAAACAGTGGTGCTGACAGAGATCTGCTGATCA
  AGCACTTACCCACAGTATCTGCAGGAGGGACATCTATATGCTCTGGCCTTCGGACAGCATTTACAGTGAT
  AAAGAAGAAGTATCCAACTGATGGATCTGAAATTGTGCTGCTGACCGATGGGGAGGACAACACCATTAGC
  AGCTGCTTTGACCTGGTGAAGCAGAGCGGGGCCATCATCCATACAGTGGCCCTGGGACCGGCTGCCGCTA
  AAGAGCTTGAGCAGCTGTCCAAAATGACAGGAGGCCTGCAGACATACTCTTCGGATCAGGTTCAGAACAA
  TGGTCTTGTTGATGCTTTCGCAGCACTCTCCTCAGGAAATGCGGCGATCGCTCAGCACTCCATCCAGCTG
  GAGAGCAGGGGAGTTAATCTCCAGAATAACCAATGGATGAATGGCTCAGTGATCGTGGACAGCTCGGTGG
  GCAAGGACACCTTGTTTCTTATCACCTGGACAACGCATCCTCCTACAATATTTATCTGGGATCCCAGCGG
  AGTGGAACAAAATGGTTTTATACTAGACACAACCACTAAGGTGGCCTACCTCCAAGTCCCAGGCACGGCT
  AAGGTTGGCTTTTGGAAATACAGCATTCAAGCGAGCTCACAGACTCTCACCTTGACTGTCACCTCCCGTG
  CAGCAAGTGCTACACTGCCTCCTATTACAGTGACCCCGGTAGTGAATAAGAACACAGGGAAATTCCCCAG
  CCCTGTAACAGTGTATGCAAGCATTCGCCAAGGAGCCTCGCCTATTCTCAGGGCCAGCGTCACAGCCTTG
  ATTGAATCTGTGAATGGAAAAACAGTAACCCTGGAATTACTGGATAACGGAGCAGGTGCCGATGCCACCA
  AGAATGATGGTGTCTACTCAAGGTTTTTTACAGCTTTTGATGCAAATGGTAGATACAGCGTTAAAATATG
  GGCTCTGGGAGGAGTCACTTCAGACAGACAGAGAGCAGCACCTCCGAAGAACAGAGCCATGTACATAGAT
  GGCTGGATTGAGGATGGTGAAGTAAGAATGAACCCACCACGTCCTGAAACTAGTTATGTTCAAGACAAGC
  AGCTGTGCTTCAGCAGGACATCTTCAGGGGGATCGTTTGTGGCCACCAATGTCCCCGCAGCAGCTCCCAT
  TCCTGACCTCTTTCCACCCTGTCAAATCACTGACCTGAAGGCCAGCATCCAAGGGCAGAACCTGGTGAAT
  CTGACGTGGACGGCTCCTGGGGATGACTACGACCACGGGAGAGCTTCCAACTACATCATCCGAATGAGCA
  CCAGTATCGTTGATCTCAGGGACCACTTCAACACCTCACTCCAAGTGAACACTACCGGTCTTATCCCCAA
  AGAGGCCAGCTCTGAGGAAATCTTTGAGTTTGAACTGGGAGGCAACACTTTTGGAAATGGCACAGATATC
  TTCATTGCTATCCAGGCTGTGGATAAGTCCAATCTGAAATCAGAAATCTCCAACATTGCACGGGTGTCTG
  TGTTCATCCCCGCTCAGGAGCCGCCCATTCCCGAAGACTCAACTCCCCCTTGTCCTGACATCAGCATCAA
  CAGCACCATTCCTGGCATCCACGTGCTGAAGATAATGTGGAAGTGGCTAGGGGAAATGCAGGTGACACTA
  GGTTTGCACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: AscI-MluI
• ACCN: NM_017474
• Insert Size: 2742 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017474.2, NP_059502.1
• RefSeq Size: 2935 bp
• RefSeq ORF: 2742 bp
• Locus ID: 23844
• UniProt ID: Q9D7Z6
• Cytogenetics: 3 69.26 cM
• Gene Summary: May be involved in mediating calcium-activated chloride conductance. May play critical roles in goblet cell metaplasia, mucus hypersecretion, cystic fibrosis and AHR. May be involved in the regulation of mucus production and/or secretion by goblet cells. Involved in the regulation of tissue inflammation in the innate immune response. May play a role as a tumor suppressor. Induces MUC5AC.[UniProtKB/Swiss-Prot Function]