Nlrp6 (NM_001081389) Mouse Untagged Clone

CAT#: MC222390

Nlrp6 (untagged) - Mouse NLR family, pyrin domain containing 6 (Nlrp6), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Nlrp6
• Synonyms: AI504961; Nalp6; Navr/Avr; Pypaf5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222390 representing NM_001081389
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATGCCGCTGGAGCCTCCTGCTCCAGCGTGGATGCAGTGGCAAGGGAGCTGCTTATGGCTACACTGG
  AGGAGCTGAGCCAGGAGCAGCTGAAGCGCTTCCGCCACAAGCTAAGGGATGCGCCCCTGGATGGCCGCAG
  CATCCCGTGGGGGCGACTGGAGCGCTCAGACGCTGTGGACCTTGTCGACAAGCTCATTGAGTTCTATGAG
  CCAGTGCCAGCTGTAGAAATGACCCGGCAGGTCCTGAAGAGGTCGGATATTCGAGATGTGGCCTCGCGAC
  TTAAGCAACAGCAGCTACAGAAGCTCGGCCCCACCTCGGTGCTTCTCTCCGTGTCAGCGTTCAAGAAGAA
  GTACCGCGAGCACGTGCTACGACAGCATGCTAAGGTGAAGGAGAGGAATGCTCGCTCTGTGAAGATCAAC
  AAGCGCTTCACCAAGCTGCTCATCGCTCCGGGGACCGGCGCTGTGGAGGACGAGCTGCTGGGGCCGTTGG
  GGGAGCCGGAGCCCGAACGCGCTCGGCGCTCGGACACGCACACTTTTAATCGGCTCTTCCGGGGAAATGA
  TGAAGAGAGCTCGCAGCCGCTGACCGTGGTGCTGCAGGGCCCGGCAGGCATCGGCAAAACCATGGCCGCC
  AAGAAAATCCTCTATGACTGGGCAGCAGGTAAGCTATACCACAGCCAGGTGGACTTTGCCTTCTTCATGC
  CGTGCGGCGAGCTGCTGGAGCGGCCGGGAAAGCGCAGCTTGGCGGACCTGGTGCTGGACCAGTGCCCGGA
  CCGCGCTTGGCCAGTGAAGCGGATACTGGCGCAACCCAATCGCCTACTGTTCATCCTGGACGGTGCAGAC
  GAGCTGCCTACTTTACCATCCTCAGAGGCCACTCCCTGCAAAGACCCTTTGGAGGCTACAAGTGGCTTGA
  GAGTGCTGAGCGGGCTGCTGAGCCAGGAGCTGTTACCAGGAGCTCGCTTGCTAGTGACTACACGCCATGC
  CGCTACAGGGAGGCTGCAGGGCAGATTGTGCTCGCCACAGTGCGCAGAAATACGCGGCTTCTCAGACAAA
  GACAAAAAAAAGTATTTCTTCAAGTTCTTCCGGGACGAGAGGAAGGCAGAGCGCGCTTACCGCTTCGTGA
  AAGAGAACGAGACGCTGTTTGCACTGTGCTTTGTGCCCTTCGTGTGCTGGATCGTGTGCACAGTGCTGCA
  GCAGCAGCTAGAGCTGGGCCGGGATCTCTCTCGTACCTCCAAGACCACTACTTCTGTGTACCTGCTCTTC
  ATCACCAGCATGCTGAAGTCTGCAGGCACCAATGGACCCCGGGTTCAGGGAGAGCTGAGAACGCTGTGTC
  GCCTGGCCAGGGAGGGCATCCTGGATCATCATAAAGCACAATTCTCAGAAGAGGACCTGGAGAAATTGAA
  GCTTCGGGGTTCCCAAGTTCAGACAATATTTCTCAACAAGAAAGAGATACCAGGAGTGCTAAAAACTGAG
  GTCACCTACCAGTTCATTGACCAGAGCTTCCAGGAGTTCTTGGCTGCATTGTCATACCTACTAGAAGCTG
  AGCGAACTCCGGGGACGCCCGCAGGCGGTGTGCAGAAGCTCCTGAACTCTGACGCGGAGCTACGTGGTCA
  TCTTGCACTGACCACCCGATTCCTCTTTGGCCTGCTAAATACAGAGGGGCTTCGTGACATTGGAAACCAT
  TTTGGCTGTGTGGTGCCAGATCATGTGAAAAAGGACACCCTGCGGTGGGTACAAGGACAGAGCCACCCCA
  AGGGGCCACCAGTAGGGGCAAAAAAGACTGCTGAGCTGGAGGACATCGAGGACGCAGAGGAGGAGGAGGA
  GGAAGAGGAGGACCTCAATTTTGGACTGGAGCTGCTGTACTGCCTGTATGAGACACAGGAGGAGGATTTT
  GTTCGACAGGCTCTCAGCAGCCTTCCAGAGATAGTACTGGAGCGAGTCAGGTTGACCCGCATGGACCTTG
  AAGTTCTGAATTACTGCGTGCAGTGCTGCCCAGATGGCCAGGCTCTGAGACTGGTGAGCTGTGGGCTGGT
  GGCGGCAAAGGAGAAGAAGAAGAAGAAGAAGAGCCTGGTGAAGCGGCTGAAGGGGAGCGTTACAGGCACC
  AACCTTGTTCTTTCTCTCTACAGCTCTCAAAGCACCAAGAAACAACCCCCAGTCTCCTTGCTGCGTCCAC
  TCTGTGAGACAATGACTACCCCGAAATGTCATCTGAGTGTTCTGATCTTGTCACACTGCAGACTCCCTGA
  TGCAGTTTGCCGAGACCTTTCCGAGGCCCTGAAGGTAGCTCCTGCCCTAAGGGAGTTGGGCCTCCTCCAG
  AGCCGGCTCACCAACACAGGCCTGCGTTTACTGTGCGAAGGCCTGGCTTGGCCCAAGTGCCAGGTGAAGA
  CACTCAGGATGCAGCTGCCTGACCTCCAAGAGGTGATCAATTACTTGGTCATCGTGCTCCAGCAGAGCCC
  AGTCCTGACCACTCTGGACCTCAGTGGCTGTCAGCTGCCTGGCGTCATTGTGGAACCTCTGTGTGCAGCC
  CTGAAGCACCCTAAATGCTCCCTAAAGACCCTCAGTCTGACCTCTGTGGAGCTGAGTGAGAACTCACTGA
  GGGATCTTCAAGCTGTGAAGACATCAAAGCCAGATCTGTCCATCATATATTCAAAATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001081389
• Insert Size: 2649 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001081389.1, NP_001074858.1
• RefSeq Size: 3823 bp
• RefSeq ORF: 2649 bp
• Locus ID: 101613
• Cytogenetics: 7 F5
• Gene Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013]