Axin2 (NM_015732) Mouse Untagged Clone

CAT#: MC221990

Axin2 (untagged) - Mouse axin2 (Axin2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Axin2
• Synonyms: Axi1; Axil; Conductin
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221990 representing NM_015732
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTAGCGCCGTGTTAGTGACTCTCCTTCCAGATCCCAGCAGCAGCTTCCGCGAGGATGCTCCGCGGC
  CCCCGGTTCCGGGAGAAGAAGGGGAGACCCCACCGTGTCAGCCTAGTGTGGGCAAGGTCCAGTCCACCAA
  ACCTATGCCCGTTTCCTCTAATGCTAGGCGGAATGAAGATGGACTGGGGGAGCCCGAGGGGCGGGCCTCC
  CCCGATTCCCCTTTGACCAGGTGGACCAAGTCTTTACACTCCTTGTTGGGTGACCAGGATGGTGCATACC
  TCTTCCGGACTTTCCTGGAGAGGGAGAAATGTGTGGATACGCTGGACTTCTGGTTTGCTTGTAATGGGTT
  CAGGCAGATGAACCTGAAGGATACCAAAACTTTGCGAGTGGCCAAAGCAATCTATAAGAGGTACATTGAG
  AACAACAGCGTTGTCTCCAAGCAGCTGAAGCCCGCCACCAAGACCTACATACGAGATGGCATCAAGAAGC
  AACAGATCGGCTCGGTCATGTTTGACCAGGCACAGACCGAGATCCAGGCAGTGATGGAGGAAAATGCCTA
  CCAGGTGTTCTTGACTTCTGACATTTACCTGGAATATGTGAGGAGTGGGGGGGAAAACACAGCTTACATG
  AGTAACGGGGGACTGGGGAGCCTAAAGGTCTTATGTGGCTACCTCCCCACCTTGAATGAAGAAGAGGAGT
  GGACGTGTGCCGACCTCAAGTGCAAACTCTCACCCACCGTGGTTGGCTTGTCCAGCAAAACTCTTCGGGC
  CACCGCGAGTGTGAGATCCACGGAAACAGCTGAAAACGGATTCAGGTCCTTCAAGAGAAGCGACCCAGTC
  AATCCTTATCACGTAGGTTCCGGCTATGTCTTTGCACCAGCCACCAGCGCCAACGACAGCGAGTTATCCA
  GCGACGCACTGACCGACGATTCCATGTCCATGACGGACAGTAGCGTAGATGGAGTCCCTCCTTACCGCAT
  GGGGAGTAAGAAACAGCTCCAGAGAGAGATGCATCGCAGTGTGAAGGCCAATGGCCAAGTGTCTCTACCT
  CATTTTCCGAGAACCCACCGCCTGCCCAAGGAGATGACGCCTGTGGAACCTGCTGCCTTCGCCGCCGAGC
  TCATCTCCAGGCTGGAGAAACTGAAACTGGAGCTGGAAAGCCGCCATAGTCTGGAGGAGCGGCTGCAGCA
  GATCCGGGAGGATGAAGAAAAGGAGGGGTCTGAGCAGGCCCTGAGCTCACGGGATGGAGCACCGGTCCAG
  CACCCCCTGGCCCTCCTACCCTCCGGCAGCTATGAAGAGGACCCACAAACCATTTTGGACGACCACCTCT
  CCAGGGTCCTCAAGACCCCCGGCTGTCAATCCCCTGGTGTGGGTCGCTATAGCCCACGGTCCCGCTCCCC
  CGACCACCACCACCAGCACCACCACCATCAGCAGTGTCATACCCTTCTTCCGACTGGGGGCAAGCTGCCC
  CCCGTGGCTGCTTGCCCCCTCCTTGGAGGCAAGAGCTTCCTGACCAAACAGACGACGAAGCACGTTCACC
  ACCACTACATCCACCACCACGCTGTCCCCAAGACCAAGGAGGAGATCGAGGCAGAAGCCACACAGAGAGT
  CCGCTGCCTCTGTCCTGGGGGAACAGATTATTATTGCTACTCCAAATGCAAAAGCCACCCAAAGGCTCCA
  GAGCCCCTGCCTGGGGAGCAGTTTTGTGGCAGCAGAGGTGGTACCTTGCCAAAACGGAATGCAAAGGGCA
  CCGAACCGGGTCTTGCACTGTCGGCCAGGGATGGAGGGATGTCCAGTGCAGCGGGGGCCCCCCAGCTTCC
  TGGGGAAGAAGGAGACCGGTCACAGGATGTCTGGCAGTGGATGTTAGAGAGTGAGCGGCAGAGCAAGTCC
  AAGCCCCATAGTGCCCAAAGCATAAGAAAGAGCTACCCATTGGAGTCTGCCTGTGCGGCCCCAGGAGAAC
  GAGTCAGCCGGCACCATCTGTTGGGGGCCAGCGGACACTCCCGCTCGGTGGCCCGGGCTCACCCATTTAC
  CCAGGACCCTGCAATGCCTCCCCTTACCCCACCCAACACTTTGGCACAGCTAGAGGAAGCCTGCCGCAGG
  CTGGCAGAGGTGTCGAAGCCCCAGAAGCAGCGGTGCTGCGTGGCCAGTCAGCAGAGGGACAGGAACCACT
  CGGCTGCTGGTCAGGCAGGAGCCTCACCCTTCGCCAACCCAAGCCTGGCTCCAGAAGATCACAAAGAGCC
  AAAGAAACTGGCAAGTGTCCACGCGCTCCAGGCCAGTGAGCTGGTTGTCACCTACTTTTTCTGTGGAGAA
  GAAATTCCATACAGGAGGATGCTGAAGGCTCAAAGCTTGACCCTGGGCCACTTCAAGGAGCAGCTCAGCA
  AAAAGGGAAATTACAGGTATTATTTCAAGAAGGCGAGTGACGAATTTGCCTGCGGAGCAGTTTTTGAGGA
  GATCTGGGACGACGAGACAGTGCTCCCCATGTACGAAGGCAGGATCCTGGGCAAAGTGGAGAGGATCGAC
  TGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_015732
• Insert Size: 2523 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015732.4, NP_056547.3
• RefSeq Size: 4279 bp
• RefSeq ORF: 2523 bp
• Locus ID: 12006
• UniProt ID: O88566
• Cytogenetics: 11 71.83 cM
• Gene Summary: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.[UniProtKB/Swiss-Prot Function]