Oca2 (NM_021879) Mouse Untagged Clone

CAT#: MC221933

Oca2 (untagged) - Mouse oculocutaneous albinism II (Oca2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Oca2
• Synonyms: D7H15S12; D7Icr28RN; D7Nic1; p; p
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221933 representing NM_021879
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGCCTAGAGAACAAAGACATCAGGCTGGCCTCAGCCGTGCTGGAAGTAGAGCTACACCAGACATCTG
  CTTTGTCGGTCCCAACTTGCCCAGACCCAGGACGGCTGCTGACCGTCAAACCTGCTACCAGTAACTACAA
  GCTGGGCCAGGCAGACCCCTGCATCCCATATGCTGGCGAGGCTGCTGGGAAGAGCGTCTGTGTTCCTGAA
  CATACAGAGTTTGGCTCATTCCTCGTGAAGGGGAGCTCCAGCTTAAAAGACCTTTCTTTTAAGGAAGACA
  CTCCTCTGCTCTGGAATTCATCCCAAAAGAAAAGGTCACAGCTCATGCCTGTTCATCACCCAGAATTCAT
  AGCTACTGAAGGTTCCTGGGAAAATGGCCTTACTGCCTGGGAGCAAAAATGCATGCTGGGTAAAGAGGTT
  GCTGATTTGTCTGCATTGGCCTCCTCAGAGAAACGGGATCTTGCAGGCAGTGTCCATCTTAGAGCCCAGG
  TCTCCAAGCTTGGGTGCTGTGTGCGGTGGATAAAGATCACAGGCTTGTTTGTTTTCGTGGTGCTCTGCTC
  TATTTTATTCAGCCTGTATCCGGACCAAGGAAAGTTCTGGCAGCTGTTGGCTGTGTCACCGCTGGAAAAC
  TACTCTGTGAACCTCAGTGGTCACGCGGACTCCATGATACTTCAGCTGGACCTGGCAGGGGCCTTAATGG
  CTGGAGGACCAAGTGGTTCCGGGAAAGAAGAACATGTCGTGGTGGTGGTGACCCAGACAGACGCAGCGGG
  CAACAGACGGCGGCGACCACAGCAGCTCACCTACAATTGGACTGTCCTTTTAAATCCAAGAAGTGAGCAC
  GTGGTGGTGAGCAGAACCTTTGAGATAGTGAGCAGGGAGGCTGTTTCCATCAGCATCCAGGCCTCTCTCC
  AACAGACTCGCCTCGTTCCTCTTTTGCTGGCCCATCAGTTCCTTGGGGCAAGCGTTGAAGCACAAGTGGC
  CAGTGCGGTGGCAATCCTTGCAGGGGTTTATACTCTGATCATATTTGAGATTGTTCACAGAACCCTGGCA
  GCCATGTTGGGAGCACTTGCAGCACTAGCAGCCTTGGCTGTGGTTGGAGATAGACCCAGCCTGACCCACG
  TGGTGGAGTGGATTGATTTCGAGACTCTGGCCCTGCTGTTTGGCATGATGATCTTAGTAGCCGTATTTTC
  AGAAACAGGATTTTTTGATTACTGTGCTGTAAAGGCATATCAACTTTCTCGAGGAAGAGTGTGGGCCATG
  ATCTTCATGCTTTGTCTCATGGCTGCCATCCTTTCTGCCTTCTTAGACAATGTCACTACGATGCTCCTTT
  TTACCCCTGTCACCATAAGGTTATGTGAAGTGCTCAATCTTGATCCGAGACAAGTCCTCATTGCAGAAGT
  GATCTTCACAAACATTGGAGGAGCTGCCACTGCTATTGGGGACCCACCAAATGTTATCATTGTTTCCAAT
  CAGGAGTTGAGAAAAATGGGCCTGGACTTCGCTGGTTTCACAGCACACATGTTCCTGGGAATTTGCCTTG
  TTCTCCTGGTCTCCTTTCCCCTCCTCAGACTTCTGTACTGGAACAAAAAGCTTTATAACAAGGAGCCTAG
  TGAGATCGTCGAACTGAAGCATGAGATTCATGTCTGGCGTTTGACTGCCCAGCGCATCAGTCCAGCCAGC
  CGTGAGGAGACAGCTGTGCGTGGCTTGCTGCTGGAGAAAGTGCTTGCCCTGGAGCATCTGCTGGCTCAAA
  GGTTGCACACTTTCCACAGGCAAATTTCACAGGAAGACAAAAATTGGGAGACCAATATTCAAGAGCTACA
  AAGAAAGCACAGGATTTCAGACAGGAGTCTGCTTGTCAAGTGCCTGACGGTGCTGGGATTTGTCATCTCC
  ATGTTCTTTCTCAACTCCTTTGTCCCTGGCATTCATCTTGATCTTGGATGGATTGCTATTCTGGGTGCCA
  TCTGGTTGCTAATTTTAGCTGATATTCATGACTTTGAGATCATTCTACACAGAGTAGAGTGGGCGACTCT
  TCTCTTCTTTGCAGCACTCTTTGTGCTGATGGAGGCATTGACACATCTTCACTTAGTAGAGTATGTTGGA
  GAACAGACTGCCCTACTAATAAAGATGGTTCCAGAAGATCAGCGCTTTGCAGCTGCCATTGTCCTGATAG
  TGTGGGTCTCAGCCTTGGCATCATCCTTGATTGACAACATCCCATTTACTGCTACGATGATTCCTGTACT
  CCTGAACCTGAGCCAAGACCCTGAAATTAGTTTGCCTGCACTGCCTCTCATGTATGCCCTGGCCCTCGGT
  GCCTGCCTGGGAGGTAATGGGACACTTATCGGAGCATCCACAAATGTTGTTTGTGCAGGAATCGCAGAGA
  AGCATGGGTATGGATTCTCTTTCATGGAATTTTTCAGGTTGGGCTTCCCTGTGATGCTCATGTCCTGCAC
  CATTGGGATGTGCTATCTCCTGATTGCTCACATTGTGGTGGGATGGAATTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_021879
• Insert Size: 2502 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_021879.2, NP_068679.1
• RefSeq Size: 3120 bp
• RefSeq ORF: 2502 bp
• Locus ID: 18431
• UniProt ID: Q62052
• Cytogenetics: 7 33.44 cM
• Gene Summary: Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the postranslational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. It can modulate intracellular glutathione metabolism.[UniProtKB/Swiss-Prot Function]