Fes (NM_010194) Mouse Untagged Clone

CAT#: MC221850

Fes (untagged) - Mouse feline sarcoma oncogene (Fes), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fes
• Synonyms: AI586313; BB137047; c-fes; FPS
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221850 representing NM_010194
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCTTCTCTTCAGAGCTGTGCAGCCCCCAGGGCCACGGGGCAGTGCAGCAGATGCAGGAAGCTGAGC
  TGCGCTTATTGGAGGGCATGAGGAAGTGGATGGCCCAGAGGGTCAAGAGTGACCGGGAATATGCAGGATT
  GCTTCACCACATGTCCTTGCAGGACAGCGGAGGCCAGAGCTGGAGCAGCGGCCCCGACAGCCCTGTCAGC
  CAGTCCTGGGCAGAGATAACAAGCCAGACCGAGAACTTGAGCCGGGTGCTGCGGCAGCATGCAGAAGATC
  TGAACTCGGGGCCCTTGAGCAAACTGAGCGTGCTGATCCGGGAGCGGCAGCACCTGAGAAAGACGTACAA
  CGAGCAGTGGCAGCAGCTGCAGCAGGAGCTCACCAAGACCCACAGCCAGGACATTGAGAAGCTGAAGACT
  CAGTACCGGACCCTGGTACGAGATAGCACCCAGGCCAGGCGCAAGTACCAGGAAGCCAGCAAAGACAAGG
  ATCGAGACAAGGCCAAAGACAAGTATGTCCGGAGCCTGTGGAAGCTCTTTGCCCACCACAACCGCTACGT
  CCTGGGTGTGAGGGCCGCACAGCTGCACCACCACCACCACCACCGGTTCATGCTGCCTGGCCTGCTGCAG
  TCACTGCAGGATTTGCACGAGGAGATGGCGGGCATTCTGAAGGACATCCTGCAGGAATACCTGGAGATTA
  GCAGTCTGGTGCAGGACGATGTGGCATCCATTCACCGTGAGCTGGCTGCAGCTGCTGCTCGGATCCAGCC
  TGAGTTTGAGTACCTAGGCTTCCTGCGACAATATGGATCCACCCCTGATGTGCCACCTTGTGTCACTTTT
  GATGAGTCGCTTCTTGAAGACGGGGAACAGCTGGAGCCAGGGGAGCTGCAGCTGAACGAGTTGACCTTGG
  AGAGCGTGCAACACACGCTGACTTCTGTGACAGATGAACTGGCTGTGGCCACCAAAGAGGTGCTGAGCCG
  GCAGGAGATGGTCAGTCAGCTGCAGCGTGAGCTCCAAAGTGAGGAACAGAACACCCACCCCCGGGAACGG
  GTGCAGCTTCTGAGCAAGAGGCAGATGCTGCAAGAGGCAATACAAGGGTTGCAGATAGCACTGTGCAGCC
  AGGACAAGCTTCAGGCCCAGCAGGAACTTCTGCAGAGCAAGATGGAGCAGCTCGGCACGGGCGAGCCCCC
  AGCCGTGCCGCTCCTTCAGGATGACCGCCATTCCACCTCCTCCACGGAGCAGGAGCGAGAGGGGGGAAGG
  ACACCCACACTGGAGATCCTTAAAAGCCACTTCTCCGGAATCTTCCGCCCCAAGTTCTCTATCCCTCCAC
  CACTGCAGCTCGTGCCGGAGGTGCAGAAGCCTCTCTATGAGCAGCTGTGGTACCACGGGGCTATCCCTCG
  GGCAGAGGTAGCTGAGCTGCTAACACACTCCGGGGACTTCCTGGTTCGGGAGAGCCAGGGCAAGCAGGAG
  TATGTACTGTCTGTGATGTGGGATGGCCAGCCCCGACATTTCATCATCCAGTCCTCAGATAACCTGTACC
  GGCTGGAAGGGGATGGCTTCCCCAGCATACCTCTGCTCATCACTCACCTGCTGTCCTCCCAGCAACCCCT
  TACAAAGAAGAGTGGTGTTGTCCTGTTCAGGGCGGTGCCCAAGGACAAGTGGGTTCTGAAGCACGAGGAC
  CTGGTGCTGGGAGAGCAGATCGGAAGGGGGAACTTCGGAGAGGTGTTTAGTGGCCGCCTTCGTGCAGACA
  ATACCCCGGTGGCTGTGAAGTCTTGCCGAGAGACACTCCCACCTGACCTCAAGGCCAAGTTTCTGCAAGA
  AGCAAGGATCCTGAAACAGTACAACCACCCCAACATTGTGCGTCTCATCGGGGTCTGCACACAGAAACAG
  CCGATCTACATCGTCATGGAGCTCGTTCAAGGGGGCGACTTTCTCACCTTCCTGCGGACAGAGGGAGCCC
  GCCTGCGGGTGAAGACTCTGCTGCAGATGGTAGGGGACGCAGCTGCTGGCATGGAATACTTGGAAAGCAA
  GTGTTGTATCCACAGGGACCTGGCTGCTCGGAACTGCCTGGTGACAGAGAAGAATGTCCTGAAGATCAGC
  GACTTTGGGATGTCCCGCGAAGAAGCTGATGGGATCTATGCCGCCTCAGCGGGCCTCAGACAAGTCCCTG
  TTAAGTGGACTGCCCCTGAGGCCCTTAACTACGGACGCTACTCCTCAGAGAGTGATGTGTGGAGCTTTGG
  CATTTTGCTGTGGGAGACCTTCAGCCTGGGGGCCTCACCCTATCCCAACCTCACCAATCAGCAGACACGG
  GAGTTTGTAGAAAAGGGGCATCGTCTGCCTTGCCCAGAGCTGTGCCCTGATGCGGTCTTCAGGCTCATGG
  AGCAGTGCTGGGCCTATGAGCCTGGGCAGAGACCTAGTTTCAGCATCATCTGCCAGGAGCTCCACAGTAT
  CCGCAAGCGGCATCGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_010194
• Insert Size: 2469 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_010194.2, NP_034324.2
• RefSeq Size: 2780 bp
• RefSeq ORF: 2469 bp
• Locus ID: 14159
• UniProt ID: P16879
• Cytogenetics: 7 45.65 cM
• Gene Summary: Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, cell attachment and cell spreading. Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT. Plays a role in the regulation of mast cell degranulation. Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling. Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR. Phosphorylates BCR and down-regulates BCR kinase activity. Phosphorylates HCLS1/HS1, PECAM1, STAT3 and TRIM28.[UniProtKB/Swiss-Prot Function]