Epc1 (NM_027497) Mouse Untagged Clone

CAT#: MC221798

Epc1 (untagged) - Mouse enhancer of polycomb homolog 1 (Drosophila) (Epc1), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Epc1
• Synonyms: 2400007E14Rik; 5730566F07Rik; A930032N02Rik; mir-1893
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221798 representing NM_027497
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAGTAAACTGTCGTTTCGGGCGCGGGCGCTGGACGCCTCGAAGCCGCTGCCGGTCTTCCGCTGTGAGG
  ATCTGCCCGACCTGCACGAATACGCCTCGATAAACCGGGCCGTGCCGCAGATGCCCACCGGGATGGAGAA
  GGAAGAGGAGTCGGAACACCATCTTCAGCGGGCTATTTCTGCACAGCAGGTGTACGGCGAGAAGCGGGAT
  AACATGGTTATTCCAGTTCCTGAAGCAGAGAGTAACATCGCTTACTATGAGTCCATATACCCTGGGGAGT
  TCAGGATGCCAAAGCAGCTCATTCACATACAGCCTTTTAGCTTGGACGCTGAACAGCCTGATTACGATCT
  GGATTCTGAAGATGAAGTATTTGTGAATAAACTGAAGAAGAAAATGGACATCTGCCCATTGCAGTTTGAG
  GAGATGATTGACCGGCTAGAAAAAGGCAGCGGTCAGCAGCCAGTCAGTCTGCAGGAAGCCAAACTACTTC
  TAAAAGAAGATGATGAGTTAATTAGAGAAGTTTATGAATACTGGATTAAAAAGAGGAAAACCTGCCGGGG
  GTCATCACTTATCCCGTTGGTAAAACAGGAAAAGCGAGATGGTTCTAGCACAAATGATCCTTACGTGGCT
  TTTAGAAGACGAACTGAGAAAATGCAAACTCGGAAAAACCGTAAGAATGATGAAGCCTCATATGAGAAAA
  TGCTCAAGCTGCGCCGCGATCTCAGCCGGGCTGTCACCATCCTGGAAATGATCAAGAGACGGGAGAAGAG
  TAAACGGGAGCTGCTGCACCTGACCCTGGAAATCATGGAGAAGAGGTATAATTTAGGTGACTATAGTGGA
  GAGATCATGTCTGAGGTCATGGCACAGAGACAGCCAGTGAAGCCTACTTATGCCATCCCCATCATCCCGA
  TTACTAACAGCAGCCAGTTCAAACACCAGGATGCCACGGACTCGAAGGAGTTCAAAGTTAACAAGCAAGA
  TAAGGCTGATCTTATCCGGCCGAAGCGCAAATATGAAAAGAAGCCCAAAGTCTTACCCCCATCTGCTGCC
  GCCCCTCAGCAGCAGAGTCCTGCTGCACTGCCAGGCTTCAGTGCTAAAGACTTAAACCAGTACGACTTCC
  CCAGCTCAGATGAAGAGCCTCTGTCACAGGTTTTGTCTGGCTCTTCGGAAGCTGAGGAAGAGAATGACCC
  TGATGGCCCTTTTGCTTTCCGTAGGAAAGCAGGCTGTCAGTACTATGCTCCTCATTTAGACCAAACTGGC
  AACTGGCCCTGGACTAGCCCTAAAGATGGAGGCCTGGGGGATGTGCGATATAGATATTGCTTAACTACTC
  TCACCGTACCCCAGAGGTGTCTTGGATTTGCACGAAGACGGGTCGGACGTGGTGGAAGGGTCGTGCTGGA
  CAGAGCGCATTCAGACTATGACAGTATGTTTCACCACCTGGATTTGGACATGCTTTCCTCACCACAACCT
  TCTCCAGTCAATCAGTTTGCCAATACCTCAGAACCCAATACCTCGGACAGATCTTCCTCTAAAGACCTCA
  GTCAGATACTAGTCGATATCAAATCATGTAGATGGCGGCACTTTAGGCCTCGGACACCATCCCTGCCTGA
  CAGTGACAGTGGTGAACTCTCCAGTAGAAAGTTACACAGGAGTATCAGTCGAGCAGGAGCAGCACAGCCT
  GGGGCCCACACGTGCAGCACCTCCACCCAGAACAGAAGTAGCAGTGGCTCAGCACACTGTGCATTCACAG
  CCGAACAGTACCAGCAGCACCAGCAGCAGCTGGCACTCATGCAGCAGCAGCAGCTTGCGCAGACTCAGCA
  GCAGCAGCAAGCAAATAGTAGTTCCTCTGCCGCCGCGCAACAGGGTTTTGTTTCTAAGACGTTGGACTCT
  GCTAGTGCACAGTTTGCTGCTTCTGCTTTGATGACGTCGGAACAGCTGCTGGGGTTCAAGGTGAAGGATG
  ATGTGGTGCTCGGGCTCGGGGTGAATGGCGTCCTTCCTGCCTCAGGAGTATACAAGGGCTTACACCTCAG
  TAGCACTACACCAACGGCACTTGTACATACGAGTCCTTCGACAGCAGGTTCAACTTTGTTACAGCCTTCA
  AATATTACACAGACTTCGGGTTCCCACAGCTCACTGAGTCACCAAGTAACTGCTGCCAGCTCTGCAACAA
  CTCAGGTTCTGTTTGGGAACAACATCCGATTAACTGTCCCCTCATCTGTCCCCACTGTCAACTCTGTCAC
  CCCAATAAACGCACGGCATATACCTAGGACTTTAAGTGCTGTTCCGCCATCTGCCTTAAAGCTGGCTGCT
  GCAGCAAATTGTCAAGTTTCCAAGGTCCCCTCCTCATCCTCTGTAGATTCAGTTCCAAGGGAAAATCATG
  AATCGGAAAAGCCAGCACTGAACAACATAGCAGACAACACAGTAGCAATGGAGGTGACGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_027497
• Insert Size: 2442 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_027497.3, NP_081773.1
• RefSeq Size: 3983 bp
• RefSeq ORF: 2442 bp
• Locus ID: 13831
• UniProt ID: Q8C9X6
• Cytogenetics: 18 A1
• Gene Summary: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) represents the longest transcript and encodes the longest isoform (2).