Tmprss6 (NM_027902) Mouse Untagged Clone

CAT#: MC221746

Tmprss6 (untagged) - Mouse transmembrane serine protease 6 (Tmprss6), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Tmprss6
• Synonyms: 1300008A22Rik
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221746 representing NM_027902
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCGAGATGTTTCCAGCTCCCCTGTTCTACCAGGATGCCCACCACCGAGGTCCCCCAAGCGGCTGATG
  GTCAGGGCGATGCGGGTGATGGAGAGGAAGCTGCTGAGCCAGAGGGGAAGTTCAAGCCCCCAAAAAACAC
  CAAGAGAAAAAACCGGGACTACGTCCGCTTCACGCCACTGTTGCTGGTCTTGGCTGCGCTGGTCTCAGCA
  GGGGTCATGCTTTGGTATTTCCTAGGGTACAAAGCGGAAGTGACCGTAAGCCAGGTGTACTCTGGCAGCC
  TCCGGGTGCTCAACCGTCATTTCTCCCAGGACCTGGGCCGACGGGAGTCTATTGCTTTCCGCAGTGAATC
  TGCCAAAGCCCAGAAGATGCTCCAAGAACTGGTTGCCAGCACCCGCCTGGGTACTTACTACAACTCTAGT
  TCTGTCTACTCCTTTGGGGAGGGACCCCTCACCTGCTTCTTCTGGTTTATCCTTGACATCCCTGAGTACC
  AGCGACTGACCCTGAGCCCTGAAGTAGTGCGCGAGCTCCTGGTGGATGAGCTACTGTCCAACAGCTCAAC
  CCTGGCTTCCTATAAGACCGAATATGAGGTGGACCCGGAAGGCCTGGTGATCCTGGAAGCCAGTGTGAAC
  GACATAGTCGTACTGAATTCCACGCTGGGCTGTTATCGCTACAGCTATGTGAACCCAGGCCAGGTCCTCC
  CATTGAAGGGGCCTGACCAGCAGACCACAAGCTGCCTGTGGCATCTGCAAGGGCCCGAAGACCTCATGAT
  CAAAGTGCGGCTGGAGTGGACCCGGGTCGATTGCAGAGACAGGGTGGCGATGTACGACGCAGCTGGGCCC
  CTGGAGAAGAGACTTATCACCTCGGTCTATGGGTGCAGCCGCCAGGAACCTGTGATGGAGGTGCTGGCAT
  CGGGCTCCGTCATGGCCGTGGTGTGGAAAAAGGGCATGCATAGCTACTATGACCCTTTCCTGCTCTCAGT
  GAAGTCTGTGGCCTTCCAGGACTGCCAGGTGAACCTGACACTGGAGGGCCGGCTGGACACACAGGGCTTC
  CTCCGTACACCCTACTACCCCAGTTACTACTCTCCCAGTACCCACTGCTCCTGGCATCTCACGGTACCCT
  CTCTGGACTACGGCTTGGCGCTCTGGTTCGATGCCTACGCACTGAGGAGGCAGAAGTACAACCGACTGTG
  TACTCAGGGCCAGTGGATGATCCAGAACAGGAGGCTGTGTGGCTTCCGTACCCTGCAGCCATATGCTGAG
  AGGATCCCCATGGTGGCCTCAGATGGTGTCACCATCAACTTCACCTCCCAGATCTCCCTCACAGGCCCGG
  GTGTGCAAGTGTACTACAGCTTGTACAACCAATCAGACCCCTGCCCTGGTGAGTTCCTCTGCTCTGTGAA
  TGGACTGTGTGTCCCTGCGTGTGACGGGATCAAGGACTGCCCCAATGGCCTGGATGAGAGAAACTGTGTC
  TGCAGAGCCATGTTCCAGTGCCAAGAGGACAGCACGTGCATTTCACTGCCTAGAGTCTGTGACCGGCAGC
  CCGACTGTCTCAATGGCAGTGACGAAGAACAGTGCCAAGAAGGAGTGCCCTGTGGGACATTCACTTTCCA
  GTGTGAGGACCGGAGCTGTGTGAAGAAGCCCAACCCAGAGTGTGACGGCCAGTCAGATTGCAGAGACGGC
  TCAGATGAGCAACACTGTGACTGTGGCCTCCAGGGCCTCTCCAGCCGTATTGTGGGCGGGACCGTGTCCT
  CCGAGGGTGAGTGGCCATGGCAGGCCAGCCTCCAGATTCGGGGTCGACACATCTGTGGGGGGGCTCTCAT
  CGCTGACCGCTGGGTCATAACGGCCGCCCACTGCTTCCAGGAGGACAGCATGGCCTCCCCGAAGCTGTGG
  ACCGTGTTCCTGGGAAAGATGCGGCAGAACTCGCGCTGGCCAGGCGAGGTGTCCTTCAAGGTGAGCCGTC
  TGTTCCTGCACCCGTACCACGAGGAGGACAGCCATGACTACGACGTGGCCCTGCTGCAGCTCGACCACCC
  CGTGGTGTACTCGGCCACTGTGCGCCCCGTCTGCCTGCCTGCCCGCTCCCACTTCTTTGAGCCAGGCCAG
  CACTGCTGGATCACAGGCTGGGGAGCCCAGCGAGAGGGTGGTCCGGTGAGCAACACCCTGCAGAAGGTGG
  ACGTACAGCTGGTCCCTCAGGACCTCTGCAGTGAGGCCTACCGCTACCAGGTGTCCCCACGCATGCTCTG
  TGCTGGCTACCGCAAGGGCAAGAAAGATGCCTGCCAGGGTGACTCTGGAGGCCCACTGGTTTGCAGGGAG
  CCCAGTGGCCGCTGGTTCCTGGCAGGGTTGGTTAGCTGGGGCCTGGGCTGTGGCCGACCCAATTTCTTTG
  GCGTCTACACCCGTGTCACACGTGTGATCAACTGGATCCAGCAGGTGCTGACCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_027902
• Insert Size: 2436 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_027902.2, NP_082178.2
• RefSeq Size: 3206 bp
• RefSeq ORF: 2436 bp
• Locus ID: 71753
• UniProt ID: Q9DBI0
• Cytogenetics: 15 E1
• Gene Summary: Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Through the cleavage of HJV, a regulator of the expression of the iron absorption-regulating hormone hepicidin/HAMP, plays a role in iron homeostasis.[UniProtKB/Swiss-Prot Function]