Drc1 (NM_001033460) Mouse Untagged Clone

CAT#: MC221349

Drc1 (untagged) - Mouse coiled-coil domain containing 164 (Ccdc164), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Drc1
• Synonyms: b2b1654Clo; Ccdc164; Gm1060
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221349 representing NM_001033460
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAATCCCTCAGGAACCATTGGGGTCCTAGAGCAGAATGGGGAAGAACACTTAGCCACCCCGATTCTCG
  GACCCTCGGTGCATTCGGATAACCCGCAGGAGCGGATCCAGGCCCGGCGCCTGCGCATCGCTGCTCGTCA
  GGAAGCCCGAAGGCGGGAAGCCCTGGGAGAGTATTTGGACGGGAAGAAGGAGAGTGAGGAGGAGCAGAGC
  AAGAGCTACAAACAGAAAGAAGAGAGCCGCCTGAAACTGACTAAACTCCTGCTCTGCGGGACCGAGTTGG
  TGACAAATATTCAGGTGGCTGCAGACGTCAGAGAGATCCACAGGAGGGTTGAAGAGGAGGAGACAAAGCG
  GCAGAGACTGGAGAAGCTGGAGAATGAAGTTAAGACCAGCCAGGATAAATTTGATGAAATCACGGCGAAG
  TGGGAGGAGGGCAGACGGAAGCGGATTCCCCAGGAACTGTGGGAGATGCTCAACAGCCAGCAGGTGCACT
  GTGCTGAGCTCATAGAAGACAAGAACAAGCTGGCCAACGAGCTGCAGCAGGAGTTAAAAATAAAGGATGA
  CCAGTATGTGAAGGACTTGAAGAAACAGTCGGAAGACATCACCCTGATTCTGGAGAGAATGGAGGAGCAG
  GTGAAGAATGTGATGAAGAACTTCCGCCAGGAGCTGATTCACATCGAGAAAGCCTTTGAGTCAGAACGGC
  AAGAACTGCTATCCAGCAATAAGAAGAAATGGGAGCGAGCCCTGCAGGCTCACAATGCCAAGGAGCTGGA
  GTACCTCACCAACCGCATGAAGAAGGTGGAGGACTACGAGAAGCAGCTCAACAAGCAGCGGGTCTGGGAC
  TGTGAGGAGTACAACACAATCAAGATCAAGCTAGAGCAGGATGTGCAGATTCTTGAGCAACAGCTTCAGC
  AGATGAAAGCAACTTACCAGCTAAACCAAGAGAAGCTGGAGTACAACTTTCAGGTCCTGAAGAAGAGAGA
  TGAAGAGAGCACAGTGATCAAGTCCCAGCAGAAGAGGAAACTGAACCGCCTGCACGATGTCGTCAACAAT
  CTGAGAACAAAATACACCAAGCAGATACGGCAGTTTCAGGATGACAACCAGTCCCTGACCTCCGACTACA
  AACGGCTTGTGACGCAATTCAAGGACCTACAGAAAGCCTTGAGACACTTCATCATCATCGATGAGGAGAA
  GTTTCGGGAGATTTGGCTGATGAATGAAGCAGAGGCGAAGGAACTGGCACAAAGAGCCTTTGATGTGGAC
  AGGATCATCCATTCCCAGCACCTGGGCTTACCCTGGAATATGCCTGACTTGTGGTTCCTGAATAACGTGG
  GGCCGATTTCCCTGCAGCAGCAGAAGTCAGTCACACAAATACTGGAGGAACTGCTGTTGCAGACAGAGGA
  TGAGGCCACAGAGGCAGCCATGTCGGAAGACGAGGATTACATGGACCTGCCCAATCAAATTTCAGCCAAA
  ACCACCACAAAGGTCCTGATGCTCCTGTGTGATGAGTCGGGTTTCCTCATAGAGAGCAAACTACTGAGTC
  TGCTCCACCCCCTGGAGAAGAGTGAATGCTATCTGCTGAGGTTGGACGCCATCTTCTCCGCCCTGGCAAT
  CGAAGACGAGGATGACTTATACAAGCTGGTAAACTTCTTCCTTCGATACCGAGCCCACCGTCTATCCTCT
  GCCCAGGCCAGTTCCTCCATTCATAGCAATGTGGAGCGTACAAGCCTGATGTCAGCACTAGAGCGTTTGA
  GTCTGATGTCCCAGACAGACAAGGGAAGCATGGTGTCCAAATCAGATCAGGAGCCCACAGAGCAGGAGGA
  CGAGCAGGAAGGTGACAACGCAAGCCTCTCGAGCAGGGAGTTGGAAGAGCAGGAGGACCTGTCATCACCC
  AGGTTCATCCACCCCAATGATGTTCTCAAGATTCTGGAGGCCTTTGTCACGGGGCTGAAGAAGCCTAAGG
  ACGCTCAGCCAGTACTGAAATTGAAGAAAGAGACTCGAGATAACTCGAAGGACACGGAGTACTGGGAATC
  CCTGGCTGCGGTTATTCCTTTCTTCAAGCAGAACCTCTGGGATGCGCTGTACAAGGCCTTGGAGAAATAC
  TATCTCGTGCTGACCGAGAGGGCCAAGCTGCTGATGGAGAATGAGTCTCTGGAGCAGCAGAATGCAGAGA
  TGCAGTCCCTGCTGCAGCAGTATCTCCAGGCCAAGGTAAACACAGAACTGCAGATCCCACCAACTCAGGG
  CTTCCGGATGCCCTCAAAATGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001033460
• Insert Size: 2262 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001033460.3, NP_001028632.1
• RefSeq Size: 2485 bp
• RefSeq ORF: 2262 bp
• Locus ID: 381738
• UniProt ID: Q3USS3
• Cytogenetics: 5 B1
• Gene Summary: Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]