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Aplp2 (NM_001102455) Mouse Untagged Clone

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SKU
MC221279
Aplp2 (untagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2), transcript variant 1, (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $1,101.00
5 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Aplp2
Synonyms AI790698; APLP-2; CDEBP
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC221279 representing NM_001102455
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCGGCCACCGGGACCGCGGCCGCTGCGGCCACCGGCAAGCTTCTTGTCCTGCTGCTGCTCGGGCTCA
CGGCGCCCGCTGCGGCTCTGGCTGGCTACATAGAGGCTCTTGCAGCCAATGCTGGAACAGGCTTCGCTGT
TGCTGAGCCTCAGATTGCGATGTTCTGTGGGAAGCTGAATATGCATGTGAACATTCAGACTGGCAAATGG
GAGCCTGACCCAACAGGCACCAAGAGCTGCCTTGGAACAAAGGAGGAGGTTCTTCAGTACTGCCAGGAGA
TATATCCAGAGCTGCAGATCACAAATGTGATGGAAGCAAACCAGCCAGTCAATATTGATAGTTGGTGCCG
AAGGGACAAAAGGCAGTGCAAGAGTCACATTGTTATACCATTCAAGTGTCTTGTGGGTGAATTTGTAAGT
GATGTCCTGCTAGTTCCAGATAACTGCCAGTTTTTCCACCAAGAGCGGATGGAGGTGTGTGAGAAGCACC
AGCGCTGGCACACGTTAGTCAAGGAGGCATGTCTGACTGAGGGGCTGACCTTATATAGCTATGGCATGCT
GCTGCCCTGCGGGGTAGACCAGTTCCATGGCACCGAGTATGTGTGCTGCCCTCAGACAAAGACTGTTGAC
TCGGACTCGACTATGTCCAAAGAAGAGGAGGAAGAGGAAGAGGATGAAGAGGACGAAGAGGAAGACTATG
ATCTTGATAAAAGTGAATTTCCTACTGAAGCAGATTTGGAAGACTTCACAGAAGCAGCAGCAGATGAGGA
AGAAGAGGATGAGGAGGAAGGGGAGGAAGTGGTGGAAGACCGTGACTACTACTATGACCCCTTTAAAGGA
GACGATTACAATGAGGAGAATCCAACCGAACCCAGCAGCGAGGGCACCATTTCAGACAAGGAGATTGTTC
ACGATGTTAAAGCTGTCTGCTCCCAGGAGGCCATGACGGGGCCCTGCCGGGCTGTGATGCCTCGTTGGTA
CTTCGACCTCTCCAAGGGAAAGTGCGTACGCTTTATATATGGCGGCTGCGGCGGCAACAGGAACAATTTT
GAGTCTGAGGATTATTGTATGGCTGTGTGTAAAGCGATGATTCCCCCGACTCCCCTGCCAACCAATGATG
TTGATGTGTATTTTGAGACCTCAGCGGATGATAATGAGCACGCCCGCTTCCAGAAGGCTAAGGAACAGCT
GGAAATTCGACATCGAAACCGAATGGACAGGGTAAAGAAGGAATGGGAAGAGGCAGAACTTCAAGCCAAG
AACCTCCCCAAGACAGAAAGACAGACCCTCATCCAGCATTTCCAAGCTATGGTTAAAGCTTTAGAGAAAG
AAGCAGCCAGTGAGAAGCAGCAGCTTGTGGAAACCCATCTGGCCCGAGTAGAAGCCATGCTGAATGACCG
CCGACGCATAGCTCTGGAAAATTACCTGGCTGCCCTGCAGTCTGACCCACCTCGGCCACATCGCATTCTT
CAAGCTCTTCGTCGTTACGTCCGTGCTGAGAACAAAGATCGCCTGCATACCATTCGTCATTACCAACACG
TGTTGGCTGTTGACCCAGAAAAGGCCGCCCAGATGAAATCCCAGGTGATGACACACCTCCATGTGATTGA
AGAAAGAAGGAACCAAAGTCTTTCTCTTCTGTACAAAGTTCCTTATGTTGCTCAAGAAATTCAAGAGGAA
ATTGATGAGCTCCTTCAGGAACAGCGAGCGGATATGGACCAATTTACCTCCTCCATCTCAGAGAACCCTG
TGGATGTCCGGGTGAGCTCTGAGGAGAGTGAGGAGATCCCGCCGTTCCACCCTCTCCATCCCTTCCCATC
CTTGTCTGAGAATGAAGGCTCTGGAATGGCAGAACAAGACGGGGGACTGATTGGTGCAGAAGAAAAAGTG
ATTAACAGCAAGAATAAAATGGATGAAAATATGGTCATTGACGAGACTCTGGATGTTAAGGAAATGATTT
TCAATGCTGAGAGAGTTGGAGGCCTTGAGGAAGAGCCGGAATCGGTGGGACCTTTAAGGGAGGATTTCAG
TTTGAGCAGCAATGCCCTTATTGGCTTGCTGGTTATCGCAGTGGCCATTGCTACGGTCATCGTTATCAGC
CTGGTGATGCTGAGGAAGAGGCAGTACGGCACCATCAGCCACGGGATTGTGGAGGTTGACCCAATGCTCA
CCCCAGAAGAGCGTCACCTGAACAAGATGCAGAACCATGGTTATGAAAACCCAACCTACAAATACCTGGA
GCAGATGCAGATTTAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_001102455
Insert Size 2256 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001102455.1, NP_001095925.1
RefSeq Size 3658 bp
RefSeq ORF 2256 bp
Locus ID 11804
Cytogenetics 9 16.66 cM
Summary May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein (By similarity). Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) lacks an alternate in-frame exon compared to variant 4. The resulting isoform (a) has the same N- and C-termini but is shorter compared to isoform d.
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Documents
Resources
"NM_001102455" in other vectors (4)
SKU Description Size Price
MG226207 Aplp2 (tGFP-tagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2) transcript variant 1, (10ug) 10 ug
$1,300.00
MR226207 Aplp2 (Myc-DDK-tagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2), transcript variant 1 10 ug
$1,100.00
MR226207L3 Lenti ORF clone of Aplp2 (Myc-DDK-tagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2), transcript variant 1 10 ug
$1,400.00
MR226207L4 Lenti ORF clone of Aplp2 (mGFP-tagged) - Mouse amyloid beta (A4) precursor-like protein 2 (Aplp2), transcript variant 1 10 ug
$1,400.00

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