Colec12 (NM_130449) Mouse Untagged Clone

CAT#: MC221214

Colec12 (untagged) - Mouse collectin sub-family member 12 (Colec12), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Colec12
• Synonyms: CL-P1; Scara4; SRCL
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221214 representing NM_130449
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAAGACGACTTTGCAGAGGAAGAGGAGGTGCAGTCCTTCGGTTACAAGAGGTTTGGTATTCAGGAGG
  GGACACAGTGTACCAAATGTAAAAATAACTGGGCACTGAAGTTTTCGATTGTATTATTATACATTCTGTG
  TGCCTTACTGACCATCACAGTAGCCATTTTGGGATATAAAGTTGTAGAGAAAATGGACAATGTCACAGAT
  GGCATGGAGACATCTCACCAGACTTATGACAACAAACTCACTGCTGTGGAAAGTGACCTGAAGAAATTAG
  GGGATCAAGCTGGGAAGAAAGCTCTAAGTACCAACTCTGAGCTTTCTACCTTCAGATCAGATATTCTGGA
  TCTCCGTCAACAACTTCAGGAGATCACAGAAAAAACCAGCAAGAACAAAGATACGCTGGAGAAGTTGCAA
  GCAAATGGGGACTCATTGGTTGATAGGCAGAGTCAGCTGAAGGAAACTCTGCAGAATAATTCTTTCCTCA
  TTACCACCGTCAACAAAACACTCCAGGCATATAATGGCTATGTCACAAATCTGCAACAAGATACTAGTGT
  GCTCCAGGGCAATCTGCAGAGCCAAATGTATTCTCAGAGCGTGGTTATCATGAACCTCAACAACCTGAAC
  CTAACCCAGGTTCAGCAGAGGAACCTTATCTCAAATCTGCAGCAGTCTGTGGATGACACAAGCCTGGCCA
  TCCAGCGAATTAAGAATGATTTCCAAAATCTGCAGCAGGTTTTCCTTCAAGCCAAGAAGGACACCGATTG
  GCTAAAGGAAAAAGTACAGAGCTTGCAGACATTGGCTGCCAACAACTCTGCCCTGGCCAAAGCCAACAAT
  GACACCCTAGAGGATATGAATAGCCAGCTCAGCTCATTCACAGGTCAGATGGACAACATTACCACTATCT
  CACAGGCCAACGAGCAGAGCCTGAAAGACCTTCAGGACTTACACAAGGATACAGAAAATAGAACAGCTGT
  CAAGTTCAGCCAACTTGAGGAACGCTTCCAGGTCTTTGAGACAGATATTGTGAACATCATTAGCAACATC
  AGCTACACAGCCCATCACCTGAGGACACTGACCAGCAATCTGAATGATGTTAGGACCACATGCACAGACA
  CCTTGACCAGACACACGGATGACCTGACCTCCTTGAATAACACACTAGTCAACATCCGCTTGGATTCTAT
  TTCTCTCAGGATGCAGCAAGACATGATGAGGTCAAAGTTAGACACTGAAGTGGCCAACTTATCAGTGGTT
  ATGGAAGAGATGAAACTGGTTGACTCCAAGCACGGTCAGCTCATCAAGAACTTTACCATTCTACAAGGTC
  CTCCTGGCCCCAGAGGTCCAAAAGGTGACAGAGGATCTCAGGGACCACCTGGTCCAACTGGCAACAAGGG
  ACAGAAAGGAGAGAAGGGAGAGCCTGGTCCACCTGGCCCTGCGGGTGAGAGGGGCACAATTGGACCAGTC
  GGCCCTCCTGGAGAGCGTGGCAGCAAAGGATCCAAAGGCTCACAGGGTCCCAAAGGATCTCGTGGGTCCC
  CAGGGAAGCCTGGCCCTCAAGGACCTAGTGGGGACCCAGGACCACCAGGTCCACCAGGCAAGGATGGACT
  CCCTGGCCCTCAGGGCCCTCCTGGCTTCCAGGGACTACAGGGCACTGTGGGTGAGCCTGGAGTACCTGGA
  CCTCGGGGGTTGCCAGGCTTGCCAGGGGTGCCAGGCATGCCTGGGCCTAAGGGACCACCTGGCCCTCCAG
  GCCCCTCAGGAGCAATGGAGCCATTGGCTCTGCAGAATGAACCAACCCCAGCATCAGAGGTCAACGGATG
  TCCGCCTCACTGGAAGAACTTCACAGATAAATGCTACTATTTTTCATTGGAAAAAGAAATTTTTGAAGAT
  GCTAAGCTTTTCTGTGAAGACAAATCTTCCCATCTCGTTTTCATAAACTCAAGAGAAGAACAGCAATGGA
  TAAAAAAGCATACCGTGGGGAGAGAAAGCCATTGGATCGGCCTCACAGACTCAGAACAGGAAAGCGAATG
  GAAGTGGCTAGACGGGTCACCTGTTGATTACAAAAACTGGAAAGCTGGACAACCAGATAACTGGGGCAGT
  GGCCATGGGCCAGGAGAAGACTGTGCTGGCTTGATTTACGCAGGACAGTGGAATGACTTCCAGTGTGATG
  AAATCAATAACTTCATTTGTGAGAAGGAAAGGGAGGCAGTACCATCATCCATATTATAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_130449
• Insert Size: 2229 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_130449.2, NP_569716.2
• RefSeq Size: 3322 bp
• RefSeq ORF: 2229 bp
• Locus ID: 140792
• UniProt ID: Q8K4Q8
• Cytogenetics: 18 A1
• Gene Summary: Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells (By similarity). Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells (By similarity).[UniProtKB/Swiss-Prot Function]