Slco4c1 (NM_172658) Mouse Untagged Clone

CAT#: MC221128

Slco4c1 (untagged) - Mouse solute carrier organic anion transporter family, member 4C1 (Slco4c1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Slco4c1
• Synonyms: 9530051F04; C330017E21Rik; OATP-H; OATP-M1; oatp-R; OATP4C1; OATPX; PRO2176; SLC21A20
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC221128 representing NM_172658
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAGGGCTCCAAAGGAATAGAGAACCCGGCTTTCGTCCCTTCCAGCCCAGGCACCCCACGCCGTGCGT
  CTGCTTCGCCCTCCCAGGTGGAGGTCTCTGCTGTGGCCTCCAGGAATCAGAATGGGGGTTCGCAGCCTCG
  GGAATCTGAGGAGCCTCAGAAGTCAACTGAGCCATCCCCGCCTTCTTCGAATCCCCCAGCTTCTGATGAG
  CCGCCGGGGTCACAGCTAAGCGAGCTTGAGGAGGGACCTTGCGGGTGGAGGGGCTTTCACCCCCAGTGTC
  TCCAGCGCTGCAACACCCCCCAAGGCTTTTTGCTTCACTACTGTCTCTTAGCCCTAACGCAAGGTATTGT
  AGTAAACGGCCTGGTAAACATTAGCATCTCCACCATTGAGAAGCGTTATGAAATGAAAAGCTCACTGACA
  GGCCTGATATCATCGAGCTACGACATCTCCTTTTGTGTGTTATCTCTATTTGTGTCTTTCTTTGGGGAGA
  GAGGACACAAACCTCGCTGGCTCGCCTTTGCATCCTTTATGATAGGCCTGGGAGCGCTGGTGTTTTCCTT
  ACCACACTTCTTCAGTGGAAGATATGAACTGGGATCCATTTTTGAAGATACGTGCTTAACAAGGAACAGT
  ACCAGATGTTCATCTTCAACCTCCCTGCTTTCTAACTACTTCTATGTCTTTGTCCTGGGACAATTGTTGC
  TGGGGACCGGAGGGACTCCGCTCTACACCCTGGGGACAGCCTTTATTGATGACTCTGTGCCCACACACAA
  ATCTTCTCTCTATATAGGTATTGGCTATTCTATGTCAATCCTAGGCCCTGCCATTGGATATGTGTTGGGT
  GGACAGCTGTTGACAATGTACATTGATATTGCTATGGGACAAAGTTCGGATCTGACTGAGGATGATCCCC
  GGTGGCTGGGGGCTTGGTGGATTGGATTCCTTTTAGCTTGGCTCTTTGCTTGGTCTTTGATAATGCCTTT
  CTCCTGTTTTCCCAAGCATTTACCAGGGACAGCAAAAATTCAAGCTGGCAAAACTTCCCAGACTCATCAA
  AATAATAGTACTTCCTTCCAACATACGGATGAAAATTTTGGAAAAAGTATTAAAGATTTTCCAACTGCTG
  TAAAGAATTTGATGAGGAATACAGTCTTTATATGTTTAGTTCTATCAACTACTTCTGAAGCATTAATTAC
  TACGGGATTTGCCACATTTTTACCTAAATTTATAGAAAATCAATTTGGATTGACATCGAGCTTTGCAGCC
  ACTCTTGGAGGGGCTGTTTTAATTCCTGGAGCTGCTCTTGGTCAAATCTTAGGTGGTGTTCTTGTTTCAA
  AATTCAAAATGAAGTGTAAAAATACAATGAAGTTTGCCTTATGTACATCTGGAGTAGCACTTGTGCTGAG
  TTTTGTATTTATTTATGCAAAATGTGAAAATGAGCCATTTGCTGGTGTGTCTGAATCATATAATGGAACT
  GGAGAAATGGGGAATTTGACTGCACCTTGTAATGCCAACTGCAACTGTTTGCGGTCCTACTATTACCCAC
  TCTGTGGAAGTGATGGAATCCAGTATTTTTCTCCCTGCTTTGCAGGTTGTTTAAACTCAGTTTCAAACAG
  GAAACCCAAGGTATATTATAATTGTTCCTGTATAGAAAGGAAAATCACTTCTACTGCAGAAAGTACTGAT
  TTTGAAGCTAAAGCTGGAAAATGTAGAACTCGGTGTTCAAACTTGCCCATATTTCTTGGCATTTTCTTCA
  TTACAGTTATCTTTACCTTTATGGCAGGCACTCCTATAACTGTGTCTATATTAAGGTGTGTTAATCACAG
  ACATCGGTCTCTAGCATTGGGAGTGCAGTTCATGCTTCTTCGATTGCTAGGTACAATACCTGGGCCAATT
  ATATTTGGTGTCATAATAGACAGCACATGTGTTCTGTGGGATGTCAATGAATGTGGAATAAAAGGAGCAT
  GTTGGATTTATGATAACATCAAGATGGCACATATGCTGGTAGCTATAAGTGTTACTTGTAAAGTTATCAC
  CATATTCTTCAATGGACTTGCGATTGTTCTCTATAAACCACCGCCCCCAGGAACAGAGGTATCATTTCAA
  AGTCAGAATGTCATTGTGTCTACTATTTCGGTCGAAGAGGATCTAGACAAAGCAGAAAATGAAGGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_172658
• Insert Size: 2169 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_172658.3, NP_766246.1
• RefSeq Size: 2394 bp
• RefSeq ORF: 2169 bp
• Locus ID: 227394
• UniProt ID: Q8BGD4
• Cytogenetics: 1 D
• Gene Summary: Organic anion transporter, capable of transporting pharmacological substances such as digoxin, ouabain, thyroxine, methotrexate and cAMP. May participate in the regulation of membrane transport of ouabain. Involved in the uptake of the dipeptidyl peptidase-4 inhibitor sitagliptin and hence may play a role in its transport into and out of renal proximal tubule cells. May be involved in the first step of the transport pathway of digoxin and various compounds into the urine in the kidney. May be involved in sperm maturation by enabling directed movement of organic anions and compounds within or between cells. This ion-transporting process is important to maintain the strict epididymal homeostasis necessary for sperm maturation. May have a role in secretory functions since seminal vesicle epithelial cells are assumed to secrete proteins involved in decapacitation by modifying surface proteins to facilitate the acquisition of the ability to fertilize the egg.[UniProtKB/Swiss-Prot Function]