Unc93b1 (NM_019449) Mouse Untagged Clone

CAT#: MC219683

Unc93b1 (untagged) - Mouse unc-93 homolog B1 (C. elegans) (Unc93b1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Unc93b1
• Synonyms: Unc-93B1; Unc93b
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219683 representing NM_019449
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGAAGGAAGTCCCAACCAGCTGCTGGTGCCCAGAACTGCAAGCCCTTGATCTGGATCTGGTCATGGAGG
  TGGAGCCTCCGCTCTACCCTGTGGCCGGGGCCGCGGGTCCTCAAGGGGATGAAGACCGGCACGGAGTTCC
  TGATGGGCCAGAGGCTCCCTTGGACGAACTCGTGGGTGCGTACCCCAACTACAATGAGGAGGAGGAAGAG
  CGCCGCTACTACCGCCGCAAGCGCCTCGGAGTGGTCAAGAACGTGCTGGCGGCCAGCACGGGTGTCACCC
  TTACTTACGGCGTCTACCTGGGCCTCCTGCAGATGCAACTGATCCTGCACTATGATGAGACCTACAGAGA
  GGTGAAGTATGGCAACATGGGGCTGCCGGACATCGATAGCAAGATGCTGATGGGTATCAACGTGACGCCT
  ATCGCTGCCCTGCTCTACACACCTGTGCTCATCAGGTTTTTTGGTACCAAGTGGATGATGTTCTTGGCTG
  TGGGCATCTATGCCCTCTTTGTCTCTACCAACTACTGGGAACGCTACTACACGCTGGTGCCCTCTGCTGT
  GGCTCTGGGCATGGCCATTGTGCCTCTGTGGGCCTCCATGGGCAACTATATCACCAGGATGTCCCAGAAG
  TACTATGAATACTCCCACTACAAGGAGCAAGATGAGCAGGGACCTCAGCAGCGCCCACCACGAGGTTCCC
  ACGCACCCTATCTCCTGGTTTTCCAGGCCATCTTCTATAGCTTCTTCCACTTGAGCTTCGCGTGTGCCCA
  GCTGCCCATGATTTACTTCCTCAACAACTACCTGTATGACCTGAACCACACACTGATCAACGTGCAGAGC
  TGCGGTACTAAGAGCCAAGGCATTCTGAATGGCTTCAACAAGACGGTCCTTCGGACGCTGCCGCGCAGCA
  AAAACCTTATTGTTGTAGAGAGCGTGCTCATGGCGGTGGCCTTCTTGGCCATGCTGATGGTGCTGGGCCT
  GTGTGGAGCCGCTTACCGGCCCACGGAAGAGATCGACCTGCGCAGCGTGGGCTGGGGCAACATCTTCCAG
  CTGCCCTTCAAACACGTGCGTGACTTTCGCTTACGCCATCTGGTGCCCTTCTTTATCTACAGTGGCTTTG
  AGGTGCTCTTTGCCTGCACTGGTTTTGCCCTGGGCTACGGCGTGTGCTCCATGGGGCTGGAGCGACTGGC
  ATACCTGCTCATAGCTTACAGCCTGGGTGCCTCAGCCTCCTCGGTTCTGGGGCTGCTGGGACTGTGGCTG
  CCTCGCTCTGTCCCGCTCGTGGCTGGGGCAGGACTGCACCTACTGCTCACCCTTAGCCTCTTTTTCTGGG
  CTCCTGCTCCTCGGGTCCTCCAGCACAGTTGGATCTTTTACTTCGTGGCTGCCCTCTGGGGTGTGGGCAG
  CGCCCTCAACAAGACCGGACTTAGCACACTCCTGGGCATCCTATATGAAGACAAAGAGAGGCAGGACTTC
  ATCTTCACCATCTATCACTGGTGGCAGGCCGTGGCCATCTTTGTTGTGTACCTGGGCTCCAGCTTGCCCA
  TGAAGGCCAAGCTGGCAGTGTTGCTGGTGACCCTGGTAGCAGCAGCAGCCTCATACCTGTGGATGGAGCA
  GAAGTTGCAGCAAGGATTGGTCCCGCGGCAGCCGCGCATTCCGAAGCCACAGCACAAAGTCCGCGGCTAC
  CGCTACCTGGAGGAGGACAACTCGGATGAGAGTGACATGGAGGGCGAGCAGGGTCAGGGGGACTGCGCAG
  AGGACGAAGCACCACAGGCAGGGCCCCTGGGTGCAGAGCCAGCTGGCCCCTGCCGCAAGCCCTGTCCCTA
  TGAACAGGCTCTGGGTGGCGATGGGCCTGAGGAGCAGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_019449
• Insert Size: 1860 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_019449.2, NP_062322.2
• RefSeq Size: 2277 bp
• RefSeq ORF: 1860 bp
• Locus ID: 54445
• UniProt ID: Q8VCW4
• Cytogenetics: 19 A
• Gene Summary: Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer variant and encodes the longer isoform (a).