Slc5a8 (NM_145423) Mouse Untagged Clone

CAT#: MC219652

Slc5a8 (untagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (Slc5a8), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Slc5a8
• Synonyms: Ait; SMCT
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219652 representing NM_145423
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGCGTCGCGGGACATCGGCAGTTTTGTGGTGTGGGACTACGTGGTGTTCGCAGGCATGCTGCTCA
  TCTCGGCGGCTATAGGCATCTATTACGCCTTCGCGGGGGGCGGCCAGCAGACCTCCAAGGACTTTCTTAT
  GGGCGGTCGCAGTATGTCCGCCGTGCCTGTGGCTCTGTCCCTCACCGCCAGCTTCATGTCCGCTGTCACT
  GTCCTGGGCACTCCTGCCGAGGTCTACCGTTTTGGGGCGATATTCAGCATCTTTGTCATCACCTACTTTT
  TTGTAGTGGTTATCAGCGCGGAGGTCTTCCTTCCAGTGTTCTATAGGCTGGGGATCACCAGCACCTACGA
  GTATTTGGAACTTCGATTTAATCGATGCATTCGTCTCTGTGGCACAATCCTCTTCATCGTTCAAACAATT
  CTGTACACTGGAATTGTGATTTATGCCCCTGCTCTGGCTTTGAATCAAGTTACAGGATTTGATCTGTGGG
  GCGCAGTGGTGGCCACAGGGGTGGTCTGCACATTCTACTGCACACTGGGCGGTCTTAAAGCAGTTGTCTG
  GACAGATGTTTTTCAAGTTGGGATCATGGTGGCTGGATTTGCATCCGTAATTATACAGGCATCAATAACT
  CAACATGGCATCAATAAGATTTTAAGTGATGCTTTTAATGGTGGAAGATTAAACTTCTGGAATTTTGATC
  CTAACCCTTTGCAAAGACACACGTTCTGGACAATTGTCATTGGAGGGACTTTTACCTGGACCACCATCTA
  TGGTGTCAACCAGTCCCAAGTGCAGAGATATATTTCCTGTAAAAGCAGACTCCATGCAAAACTGTCCCTC
  TATGTCAACCTTGTGGGCCTCTGGGTGATCCTCACCTGCTCCATATTCTGTGGGCTTGCCCTGTACTCCA
  GATACCGTGAATGTGATCCCTGGACATCTAAGAAAGTGTCAGCGATTGACCAGCTTATGCCTTATTTGGT
  GTTGGACATTTTGAAAAATTACCCTGGTGTTCCCGGACTTTTTGTGGCCTGCGCTTACAGTGGGACATTA
  AGCACAGTGTCCTCCAGTATCAATGCCTTGGCGGCAGTCACCGTGGAAGATCTCATCAAACCCCGCTTTA
  AGTCTCTCTCAGAGAAGTCTCTGTCTTGGATTTCCCAAGGAATGAGTGTTCTGTATGGAGCTCTGTGCAT
  TGGAATGGCTGCCCTGGCATCGCTGATGGGAGCCTTGTTACAGGCAGCACTCAGCATATTCGGCATGGTT
  GGTGGACCACTTCTGGGCTTGTTTTCTTTGGGCATCTTGGTCCCCTTCGCCAACTCGATTGGAGCACTCA
  CTGGTCTGTTGGCTGGATTTGCCATTTCCTTATGGGTAGGAATTGGAGCCCAGCTTTATCCTCCGCTTCC
  TGAGAGAACCTTACCATTGCCCCTTGAAACCTATGGCTGTAACATCACGCACAATGGGTCGGACTGGATG
  TCAACCACAGAAATGCCATTTTCTACTAGCGCTTTTCAAATACATAATGCGGAAAGGACTCCACTGATGG
  ACAATTGGTATTCATTATCATATCTGTACTTCAGTACTATTGGAACGCTGACAACACTGTTTGTGGGGAT
  ACTTATCAGCTTATCAACAGGAGGAAGAAAACAGAACTTAGATCCCCGATTCTTACTAACCAAACAGGAC
  TTTTTATCCAATTTTGATGTTTTTAAGAAAAGGAATCATGTTTTAAACTATAAATTGCATCCTGTGGAAG
  TTGGTGGAACTGATAACCCTGCCTTCAACCATGTTGAGCTGAACTTCACAGATCACAGTGGCAAGATCAA
  TGGGACTCGCTTGTGA
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_145423
• Insert Size: 1836 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_145423.2, NP_663398.2
• RefSeq Size: 5346 bp
• RefSeq ORF: 1836 bp
• Locus ID: 216225
• UniProt ID: Q8BYF6
• Cytogenetics: 10 C1
• Gene Summary: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.[UniProtKB/Swiss-Prot Function]