Gan (NM_001081151) Mouse Untagged Clone

CAT#: MC219558

Gan (untagged) - Mouse giant axonal neuropathy (Gan), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Gan
• Synonyms: A330045G18; gigaxonin
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219558 representing NM_001081151
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCCGAGGGCAGCGCTGTGTCCGACCCTCAGCACGCCGCGCGCCTGCTGCGGGCGCTCAGCTCGTTCC
  GGGAGGAGGCGCGTTTCTGCGACGCGCATCTGGTCCTCGACGGCGAGGAGATCCCGGTGCAGAAGAACAT
  CCTGGCGGCGGCCAGCCCGTACATCAGGACAAAGTTAAACTATAATCCTCCAAAAGATGACGGATCCACT
  TATAAGATTGAACTTGAAGGGATATCGGTAATGGTGATGAGAGAGATCCTGGATTACATCTTCAGTGGGC
  AGATCAGGTTAAATGAAGATACAATCCAGGATGTTGTGCAGGCAGCCGACCTGCTGCTGCTGACGGACCT
  GAAAACGCTGTGCTGTGAGTTCCTGGAGGGCTGCATAGCGGCGGAGAACTGCATTGGCATCCGGGACTTT
  GCGCTGCACTACTGCCTGCACCACGTGCATTACCTGGCCACTGAGTACCTGGAGACCCACTTCCGAGACG
  TCAGCAGCACAGAGGAGTTCCTGGAGCTGAGTCCACAGAAACTCAAAGAAGTGATCTCTCTCGAGAAGCT
  GAACGTTGGCAACGAGAGATACGTGTTCGAGGCAGTGATTCGGTGGATAGCACACGATGTAGAGATGAGA
  AAGGTCCACATGAAGGATGTCATGTCAGCGCTGTGGGTCTCGGGGCTGGACTCCAGCTACCTGCGCGAGC
  AGATGCTGAATGAACCCTTGGTGCGAGAAATCGTCAAAGAGTGCAGCAACATCCCGCTCAGCCAGCCGCA
  GCAGGGGGAGGCCATGCTGGCCAGCTTCAAGCCCAGGGGCTACTCAGAGTGCATAGTGACCATCGGAGGG
  GAGGAGAGAGTGTCACGGAAACCCACAGCGGCCATGCGATGTATGTGCCCTCTCTACGACCCTAACCGGC
  AGCTGTGGATTGAACTGGCTCCTCTGAGCATGCCGAGAATTAACCATGGAGTTCTTTCAGCAGAAGGATT
  TCTGTTTGTGTTGGGGGGCCAAGATGAAAACAAGCAGACGCTGAGCTCAGGAGAGAAGTATGACCCAGAC
  GCTAACACGTGGACTGCGCTCCCACCCATGCATGAGGCAAGACACAACTTTGGGATCGTGGAGATAGACG
  GGATGCTCTACATCCTTGGAGGGGAGGATGGCGATCGAGAGCTCATTTCCATGGAGTGTTATGATATTTA
  TTCCAAAACCTGGACGAAGCAGCCCGACTTGACCATGGTTAGGAAGATTGGCTGCTATGCAGCTATGAAA
  AAGAAAATCTATGCCATGGGCGGAGGCTCGTATGGAAAACTGTTTGAGTCTGTGGAGTGTTACGACCCAC
  GGACCCAGCAATGGACTGCCATATGCCCACTGAAAGAGAGGAGGTTTGGAGCAGTGGCCTGTGGTGTTGC
  CATGGAGCTGTATGTGTTTGGAGGCGTCCGAAGTCGAGAGGACATCCAGGGCAGCGAGATGGTCACCTGC
  AAGTCCGAGTTCTATCATGACGAGTTTAAGAGGTGGATCTACCTTAACGATCAGAACCTATGCATCCCTG
  CCAGCTCCTCCTTTGTCTACGGAGCGGTCCCCATAGGAGCCAGTATTTATGTTATCGGAGACCTGGACAC
  AGGTACCAACTACGACTACGTGCGGGAGTTTAAGAGAAGCACGGGCACCTGGCACCACACAAAGCCACTC
  CTGCCATCTGACCTTCGGCGCACAGGCTGTGCAGCCCTGCGCATAGCCAACTGCAAGCTCTTCCGCCTGC
  AGCTGCAACAAGGCTTGTTCCGCATCCGGGTCCATTCCCCTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001081151
• Insert Size: 1794 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001081151.1, NP_001074620.1
• RefSeq Size: 2652 bp
• RefSeq ORF: 1794 bp
• Locus ID: 209239
• UniProt ID: Q8CA72
• Cytogenetics: 8 E1
• Gene Summary: Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB (By similarity). Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.[UniProtKB/Swiss-Prot Function]