Cables1 (NM_001146287) Mouse Untagged Clone

CAT#: MC219410

Cables1 (untagged) - Mouse CDK5 and Abl enzyme substrate 1 (Cables1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cables1
• Synonyms: Cables; ik3-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219410 representing NM_001146287
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCGGCGGCGACCGCCACCGCGGGCACGGCCGCCTGCAGCAGCAGCAGCAGCAGTCGCGGCGGCAGCA
  CGGACGCCGCGGCCACCAGCGGGGTGCAGCCGCCGCCGCCTCCTCCGGCCACCGCGCCGCCGGAACCTCT
  TCGTAAGCCGCGCATGGACCCGCGGCGCCGCCAGGCTGCCCTGTCCTTCCTCACCAACATTTCTCTGGAC
  GGACGGCCTCCGCTGCAGGACCACGAGTGGGGCGGCGGCGAGGAGGGCGGCGGGACCAAGCCCGGAGCAA
  GGGCTCGGCTCAGCCTGCTGGCCGCTGGCTGCAACGCGTTCTCGGCACCGGGCACCGCGGCCGCGCCGTG
  GACCGCCGGCTCGGGTTCCAGCCCTTGCCCGCTGCCGCCGTCTCTGGTCCCCCGGGTGTTGGGAGAGCCA
  TCTCAGCCGCCCCGTTCAGCTCCAGCTGTCACCGGTGCTCAGCTGCAGTTGCCTGACGGGCCGGGAGGCG
  CCGGACAGGAGGAGCTGGAGGAGGACGATGCCTTCACCAACGTGCAGGTGCCATCGGCCAGCTTTTTGGG
  CTCCGGGACCCCCGGGAGTACGAGCGGCAGTCGGGGCCGCCTCAACTCGTTCACTCAGGGAATCCTGCCC
  ATCGCCTTCTCCAGGCAGAACTCGCAGAACTACTGCGCCTTGGAGCAGTCAGGCCAGGGCGGCAGCACCA
  GCGCCTTGGAGCAGCTGCAGAGGTCCAGACGTCGCCTCATCTCCCAGAGATCATCTTTGGAGACCCTGGA
  AGATATTGAAGAGAATGCCCCTCTCCGGAGATGTCGAACACTCTCAGGTTCTCCCAGACCAAAGAATTTC
  AAGAAAATTCATTTTATCAAGAATATGCGACAGCACGATACCAAGAATGGCAGAATAGTCCTTATCAGTG
  GCAGAAGATCCTTCTGTAGTATATTTTCCGTGCTGCCGTATCGAGACAGTACCCAAGTCGGGGACCTGAA
  GTTGGATGGAGGGAGGCAGTCAGCAGGGGCCATGAGCCTGAAGGAGATCATTGGCCTTGAAGGTGTGGAA
  CTGGGTGCCGATGGGAAGACAGTGTCTTATACCCAGTTTCTACTACCCACAAATGCCTTTGGGAACCGTA
  GAAATACCATAGACTCCACCGCCTCCTTCTCCCAGTTTCGGAGCCTGAGCCACCGAAGCCTCTCCATGGG
  CCGGGCTGGCAGCACCCAGGGGAGCCTTGATGCAGGAAGTGACCTGGGAGACTTTATGGACTATGACCCA
  AACCTCCTGGATGACCCCCAGTGGCCTTGCGGCAAGCACAAGCGAGTTCTGACCTTCCCTTCATACATGA
  CCACAGTGATTGACTACGTGAAGCCCTCAGATCTCAAGAAGGACATGAATGAAACCTTCAAGGAGAAGTT
  TCCTCACATTAAATTAACACTCAGCAAAATCAGGAGCCTGAAAAGAGAGATGCGGAAGCTTGCCCAGGAG
  GACTGTGGCTTTGAGGAGCCCACGGTGGCCATGGCCTTTGTCTACTTTGAGAAGCTGGCCCTCAGGGGGA
  AGCTGAACAAGCAGAACCGGAAGCTCTGTGCGGGAGCCTGTGTGCTGCTAGCGGCCAAGGTCGGAAGTGA
  CCTCAGAAAGCACGAGGTCAAGCACCTGATTGACAAACTGGAAGAGAAGTTCCGACTGAACAGACGAGAA
  CTGATTGCCTTTGAATTCCCAGTGTTAGTGGCCTTGGAGTTTGCACTTCACCTGCCAGAGCACGAAGTCA
  TGCCCCACTATAGACGCCTGATCCAGAGCTCCTAG
  
  AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
  TGGATTACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001146287
• Insert Size: 1785 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001146287.1, NP_001139759.1
• RefSeq Size: 3343 bp
• RefSeq ORF: 1785 bp
• Locus ID: 63955
• Cytogenetics: 18 A1
• Gene Summary: Cyclin-dependent kinase binding protein. Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition. Positively affects neuronal outgrowth. Plays a role as a regulator for p53/p73-induced cell death (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.