Smad6 (NM_008542) Mouse Untagged Clone

CAT#: MC218743

Smad6 (untagged) - Mouse MAD homolog 6 (Drosophila) (Smad6), (10ug)


  "NM_008542" in other vectors (7)

Reconstitution Protocol

USD 732.00

5 Weeks*

Size
    • 10 ug

Product Images

Frequently bought together (3)
Rabbit Polyclonal Anti-Smad6 Antibody
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Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

USD 59.00

Other products for "Smad6"

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Smad6
Synonyms b2b390Clo; Madh6
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC218743 representing NM_008542
Red=Cloning site Blue=ORF Orange=Stop codon

CTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCCGGCGC
GCCAGATCTCAAGCTT

ATGTTCAGGTCTAAACGTTCGGGGCTGGTGCGGCGACTTTGGCGAAGTCGTGTGGTCCCTGATCGGGAGG
AAGGCAGCGGCGGCGGCGGTGGTGTCGACGAGGATGGGAGCCTGGGCAGCCGAGCTGAGCCTGCCCCGCG
GGCACGAGAGGGCGGAGGCTGCAGCCGCTCCGAAGTCCGCTCGGTAGCCCCGCGGCGGCCCCGGGACGCG
GTGGGACCGCGAGGCGCCGCGATCGCGGGCAGGCGCCGGCGCACAGGGGGCCTCCCGAGGCCCGTGTCGG
AGTCGGGGGCCGGGGCTGGGGGCTCCCCGCTGGATGTGGCGGAGCCTGGAGGCCCAGGCTGGCTGCCTGA
GAGTGACTGCGAGACGGTGACCTGCTGTCTCTTCTCCGAACGGGACGCAGCAGGCGCGCCCCGGGACTCT
GGCGATCCCCAAGCCAGACAGTCCCCGGAGCCGGAGGAGGGCGGCGGGCCTCGGAGTCGCGAAGCCCGCT
CGCGACTGCTGCTTCTGGAGCAGGAGCTCAAGACGGTCACGTACTCGCTGCTCAAGAGGCTCAAGGAGCG
TTCGCTGGACACGCTGTTGGAGGCTGTGGAGTCCCGAGGCGGCGTACCGGGCGGCTGCGTGCTGGTGCCG
CGCGCCGACCTCCGCTTGGGCGGCCAGCCCGCGCCACCGCAGCTGCTGCTCGGCCGCCTCTTCCGCTGGC
CAGACCTGCAGCACGCAGTGGAGCTGAAACCCCTGTGCGGCTGCCACAGCTTTACCGCCGCCGCCGACGG
GCCCACGGTGTGTTGCAACCCCTACCACTTCAGCCGGCTCTGCGGGCCAGAATCACCGCCGCCCCCCTAT
TCTCGGCTGTCTCCTCCTGACCAGTACAAGCCACTGGATCTGTCCGATTCTACATTGTCTTACACTGAAA
CCGAGGCCACCAACTCCCTCATCACTGCTCCGGGTGAATTCTCAGATGCCAGCATGTCTCCGGATGCCAC
CAAGCCGAGCCACTGGTGCAGCGTGGCGTACTGGGAGCACCGGACACGCGTGGGCCGCCTCTATGCGGTG
TACGACCAGGCTGTCAGCATTTTCTACGACCTACCTCAGGGCAGCGGCTTCTGCCTGGGCCAGCTCAACC
TGGAGCAGCGCAGTGAGTCGGTGCGGCGCACGCGCAGCAAGATCGGTTTTGGCATACTGCTCAGCAAGGA
GCCAGACGGCGTGTGGGCCTACAACCGGGGCGAGCACCCCATCTTCGTCAACTCCCCGACGCTGGATGCG
CCCGGAGGCCGCGCCCTGGTCGTGCGCAAGGTGCCACCGGGTTACTCCATCAAGGTGTTCGACTTTGAGC
GCTCAGGGCTGCTGCAGCACGCAGACGCCGCTCACGGCCCCTACGACCCGCACAGTGTGCGCATCAGCTT
CGCCAAGGGCTGGGGACCCTGCTACTCGCGACAGTTCATCACCTCCTGCCCCTGTTGGCTGGAGATCCTA
CTCAACAACCACAGATAG


AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC
TGGATTACAAGGATGACGACGATAAGGTTTAA
Restriction Sites HindIII-RsrII     
ACCN NM_008542
Insert Size 1488 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_008542.3, NP_032568.3
RefSeq Size 2971 bp
RefSeq ORF 1488 bp
Locus ID 17130
UniProt ID O35182
Cytogenetics 9 C
Gene Summary Binds to regulatory elements in target promoter regions (By similarity). May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding (By similarity). Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes.[UniProtKB/Swiss-Prot Function]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.