Slc5a8 (BC017691) Mouse Untagged Clone

CAT#: MC218578

Slc5a8 (untagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Slc5a8
• Synonyms: MGC19357, Ait
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC017691
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCGGTCGCAGTATGTCCGCCGTGCCTGTGGCTCTGTCCCTCACCGCCAGCTTCATGTCCGCTGTCA
  CTGTCCTGGGCACTCCTGCCGAGGTCTACCGTTTTGGGGCGATATTCAGCATCTTTGTCATCACCTACTT
  TTTTGTAGTGGTTATCAGCGCGGAGGTCTTCCTTCCAGTGTTCTATAGGCTGGGGATCACCAGCACCTAC
  GAGTATTTGGAACTTCGATTTAATCGATGCATTCGTCTCTGTGGCACAATCCTCTTCATCGTTCAAACAA
  TTCTGTACACTGGAATTGTGATTTATGCCCCTGCTCTGGCTTTGAATCAAGTTACAGGATTTGATCTGTG
  GGGCGCAGTGGTGGCCACAGGGGTGGTCTGCACATTCTACTGCACACTGGGCGGTCTTAAAGCAGTTGTC
  TGGACAGATGTTTTTCAAGTTGGGATCATGGTGGCTGGATTTGCATCCGTAATTATACAGGCATCAATAA
  CTCAACATGGCATCAATAAGATTTTAAGTGATGCTTTTAATGGTGGAAGATTAAACTTCTGGAATTTTGA
  TCCTAACCCTTTGCAAAGACACACGTTCTGGACAATTGTCATTGGAGGGACTTTTACCTGGACCACCATC
  TATGGTGTCAACCAGTCCCAAGTGCAGAGATATATTTCCTGTAAAAGCAGACTCCATGCAAAACTGTCCC
  TCTATGTCAACCTTGTGGGCCTCTGGGTGATCCTCACCTGCTCCATATTCTGTGGGCTTGCCCTGTACTC
  CAGATACCGTGAATGTGATCCCTGGACATCTAAGAAAGTGTCAGCGATTGACCAGCTTATGCCTTATTTG
  GTGTTGGACATTTTGAAAAATTACCCTGGTGTTCCCGGACTTTTTGTGGCCTGCGCTTACAGTGGGACAT
  TAAGCACAGTGTCCTCCAGTATCAATGCCTTGGCGGCAGTCACCGTGGAAGATCTCATCAAACCCCGCTT
  CAAGTCTCTCTCAGAGAAGTCTCTGTCTTGGATTTCCCAAGGAATGAGTGTCCTGTATGGAGCTCTGTGC
  ATTGGAATGGCTGCCCTGGCATCGCTGATGGGAGCCTTGTTACAGGCAGCACTCAGCATATTCGGCATGG
  TTGGTGGACCACTTCTGGGCTTGTTTTCTTTGGGCATCTTGGTCCCCTTCGCCAACTCAATTGGAGCACT
  CACTGGTCTGTTGGCTGGATTTGCCATTTCCTTATGGGTAGGAATTGGAGCCCAGCTTTACCCTCCGCTT
  CCTGAGAGAACCTTACCATTGCCCCTTGAAACCTATGGCTGTAACATCACGCACAATGGGTCGGACTGGA
  TGTCAACCACAGAAATGCCATTTTCTACTAGCGCTTTTCAAATACATAATGCGGAAAGGACTCCACTGAT
  GGACAATTGGTATTCATTATCATATCTGTACTTCAGTACTATTGGAACGCTGACAACACTGTTTGTGGGG
  ATACTTATCAGCTTATCAACAGGAGGAAGAAAACAGAACTTAGACCCCCGATTCTTACTAACCAAACAGG
  ACTTTTTATCCAATTTTGATGTTTTTAAGAAAAGGAATCATGTTTTAAACTATAAATTGCATCCTGTGGA
  AGTTGGTGGAAATGATAACCCTGCCTTCAACCATGTTGAGCTGAACTTCACAGATCACAGTGGCAAGATC
  AATGGGACTCGCTTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: BC017691
• Insert Size: 1698 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC017691, AAH17691
• RefSeq Size: 5351 bp
• RefSeq ORF: 1697 bp
• Locus ID: 216225
• Cytogenetics: 10 C1
• Gene Summary: Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.[UniProtKB/Swiss-Prot Function]