Bmpr1a (NM_009758) Mouse Untagged Clone

CAT#: MC217555

Bmpr1a (untagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bmpr1a
• Synonyms: 1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC217555 representing NM_009758
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGACTCAGCTATACACTTACATCAGATTACTGGGAGCCTGTCTGTTCATCATTTCTCATGTTCAAGGGC
  AGAATCTAGATAGTATGCTCCATGGCACTGGTATGAAATCAGACTTGGACCAGAAGAAGCCAGAAAATGG
  AGTGACTTTAGCACCAGAGGATACCTTGCCTTTCTTAAAGTGCTATTGCTCAGGACACTGCCCAGATGAT
  GCTATTAATAACACATGCATAACTAATGGCCATTGCTTTGCCATTATAGAAGAAGATGATCAGGGAGAAA
  CCACATTAACTTCTGGGTGTATGAAGTATGAAGGCTCTGATTTTCAATGCAAGGATTCACCGAAAGCCCA
  GCTACGCAGGACAATAGAATGTTGTCGGACCAATTTGTGCAACCAGTATTTGCAGCCTACACTGCCCCCT
  GTTGTTATAGGTCCGTTCTTTGATGGCAGCATCCGATGGCTGGTTGTGCTCATTTCCATGGCTGTCTGTA
  TAGTTGCTATGATCATCTTCTCCAGCTGCTTTTGCTATAAGCATTATTGTAAGAGTATCTCAAGCAGGGG
  TCGTTACAACCGTGATTTGGAACAGGATGAAGCATTTATTCCAGTAGGAGAATCATTGAAAGACCTGATT
  GACCAGTCCCAAAGCTCTGGGAGTGGATCTGGATTGCCTTTATTGGTTCAGCGAACTATTGCCAAACAGA
  TTCAGATGGTTCGGCAGGTTGGTAAAGGCCGCTATGGAGAAGTATGGATGGGTAAATGGCGTGGTGAAAA
  AGTGGCTGTCAAAGTGTTTTTTACCACTGAAGAAGCTAGCTGGTTTAGAGAAACAGAAATCTACCAGACG
  GTGTTAATGCGTCATGAAAATATACTTGGTTTTATAGCTGCAGACATTAAAGGCACTGGTTCCTGGACTC
  AGCTGTATTTGATTACTGATTACCATGAAAATGGATCTCTCTATGACTTCCTGAAATGTGCCACACTAGA
  CACCAGAGCCCTACTCAAGTTAGCTTATTCTGCTGCTTGTGGTCTGTGCCACCTCCACACAGAAATTTAT
  GGTACCCAAGGGAAGCCTGCAATTGCTCATCGAGACCTGAAGAGCAAAAACATCCTTATTAAGAAAAATG
  GAAGTTGCTGTATTGCTGACCTGGGCCTAGCTGTTAAATTCAACAGTGATACAAATGAAGTTGACATACC
  CTTGAATACCAGGGTGGGCACCAAGCGGTACATGGCTCCAGAAGTGCTGGATGAAAGCCTGAATAAAAAC
  CATTTCCAGCCCTACATCATGGCTGACATCTATAGCTTTGGTTTGATCATTTGGGAAATGGCTCGTCGTT
  GTATTACAGGAGGAATCGTGGAGGAATATCAATTACCATATTACAACATGGTGCCCAGTGACCCATCCTA
  TGAGGACATGCGTGAGGTTGTGTGTGTGAAACGCTTGCGGCCAATCGTGTCTAACCGCTGGAACAGCGAT
  GAATGTCTTCGAGCAGTTTTGAAGCTAATGTCAGAATGTTGGGCCCATAATCCAGCCTCCAGACTCACAG
  CTTTGAGAATCAAGAAGACACTTGCAAAAATGGTTGAATCCCAGGATGTAAAGATTTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_009758
• Insert Size: 1599 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_009758.4, NP_033888.2
• RefSeq Size: 5481 bp
• RefSeq ORF: 1599 bp
• Locus ID: 12166
• UniProt ID: P36895
• Cytogenetics: 14 20.81 cM
• Gene Summary: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149). Mediates induction of adipogenesis by GDF6 (PubMed:23527555).[UniProtKB/Swiss-Prot Function]