Asic2 (NM_001034013) Mouse Untagged Clone

CAT#: MC217272

Asic2 (untagged) - Mouse amiloride-sensitive cation channel 1, neuronal (degenerin) (Accn1), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Asic2
• Synonyms: Accn1; ACIC2; BNaC1; BNaC1a; BNC1; Mdeg
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Restriction Sites: SgfI-MluI
• ACCN: NM_001034013
• Insert Size: 1539 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001034013.2, NP_001029185.1
• RefSeq Size: 2643 bp
• RefSeq ORF: 1539 bp
• Locus ID: 11418
• UniProt ID: Q925H0
• Cytogenetics: 11 48.43 cM
• Gene Summary: Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (MDEG1) has an alternate 5' terminal exon including the 5' UTR and 5' coding region, compared to variant MDEG2. The resulting isoform (MDEG1) is shorter and has a distinct N-terminus, compared to isoform MDEG2.