Prr7 (NM_001030296) Mouse Untagged Clone

CAT#: MC214943

Prr7 (untagged) - Mouse proline rich 7 (synaptic) (Prr7), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Prr7
• Synonyms: XM_484263
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC214943 representing NM_001030296
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGTGATGTCCCAGGGCACCTACACGTTCCTCACTTGCTTCGCCGGCTTCTGGCTCATCTGGGGTCTCA
  TCGTCCTGCTCTGCTGCTTCTGCAGCTTCCTGCGCCGCCGCCTCAAACGGCGCCAGGAGGAGCGACTAAG
  GGAGCAGAACTTGCGTGCCCTGGAGCTGGAGCCCCTCGAGCTTGAGGGCAGCCTGGCTGGAAGTCCTCCC
  GGCCTGGCGCCGCCGCCGCCACCGCACCGCAGCCGTCTGGAGGCGCCTGTGCACGCGCACTCGCACGTGC
  ACGTGCACCCGCTGCTGCACCACGGGCCGGCGCCGCCGCACGCGCACCCGCACCCACACCATCACGCACT
  GCCGCACCCACCGCCGCCGCACCTCGCCGTGCCGCCCCGGCCCTGGAGCTATCCGCGCCAAGCGGAATCG
  GACATGTCTAAGCCGCCGTGCTACGAGGAGGCGGTGCTGATGGCCGAGCCGCCGCCTCCCTACAGCGAGG
  TGCTCACGGACACTCGCGGCCTCTACCGCAAGATCGTCACGCCCTTTCTGAGCCGCCGCGACAGCGCGGA
  GAAGCAGGAGCAGCCGCCTCCGAGTTACAAGCCTCTCTTCCTGGACCGGGGCTATACTTCGGCGCTGCAT
  CTTCCCAGCGCCCCGCGGCCCGCCGCACCCTGCCCTGCCCTCTGTCTGCAGGCGGAACGCAGCCGCCGGG
  TTTTCCCCAGCTGGACCGACTCAGAGCTCAGCAGCCGAGAGCCCCTGGAGCACGGAGCTTGGCGTCTGCC
  GGTCTCCATCCCCTTGTTCGGGAGGACTACAGCCGTATAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001030296
• Insert Size: 810 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001030296.4, NP_001025467.1
• RefSeq Size: 1360 bp
• RefSeq ORF: 810 bp
• Locus ID: 432763
• UniProt ID: Q3V0I2
• Cytogenetics: 13 B1
• Gene Summary: Acts as a synapse-to-nucleus messenger to promote NMDA receptor-mediated excitotoxicity in neurons in a JUN-dependent manner (By similarity). Inhibits ubiquitination-mediated degradation and promotes phosphorylation and transcriptional activity of transcription factor JUN (By similarity). Might play a redundant role in the regulation of T cell receptor signaling (PubMed:27657535). Might promote apoptosis in T cells (By similarity).[UniProtKB/Swiss-Prot Function]