Iqcg (NM_178378) Mouse Untagged Clone

CAT#: MC210992

Iqcg (untagged) - Mouse IQ motif containing G (Iqcg), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Iqcg
• Synonyms: 2400003L07Rik; esgd12d; G1-374-12; repro1; stubby12d
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC210992 representing NM_178378
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGACGAGGAAGAGGTGGAAGTCGTGGAGTCTCCTTCAGAGGTTTTACAACCTGAGGTCACTGTGGTGG
  TGACAGGAGAGCCTCCTGAAGCTGCAGAAGAAGATCTAGATTACGAAGAAGAGGAAGAGACCTCCCCGGA
  AGTCATAGAGACGCTGTCCCTTCTAGACGTGCTGAGGGTGTCGGCCGTCATGGAGGACGTCATTGACCAG
  CTCTCTATTCTCGGCTACATCATTCCGGTTCAGTATGAAAGAAGGCAGAGCCTCACCCAGAAAGCCAGCC
  ACGAAGGAGCATCTATGATTACAACCACACCGAAAAAATCTACTTCTTTGTTAACTAAAGAAAAATCCAT
  GATGGCAGAAAACAAACAGAGAGGGCAGGACTTTACCTTTAAAAAACCTACAAAGCAGACCATGATGACT
  CTGGAGACACTGAAGAAAATTCAGAATGACAGGCAATATTTCAGTGATGTAATTGCAAATGCCATGATGG
  AGATGCAAGATTCTGGCTCTTTCACCAGTCTCCTGAAAGCCTTGGGCAAAGAAAGAGACAGCAAAATGAA
  TTTCCATGATGTCATCACAAGGGAGGAAAAGGGAAGAAAACAGATAAAAACCCTTCAAAAACAGTTACTT
  GATGTCAAAAGGGAGCGTCAAATGCAAGTACAGAACGGGAATGAATACATTGCTCACCTCAGGGACCAGC
  TACAAGAGATGAAGGCGAAAACCAACTTGGAGAATCTTTATATGAAAAGAAATGCTGAGCTGCAGATTTC
  CCAGACCCAGAAGAAATGTAACCGAGCAGAAGAACTCTTGCTGGAGGAGATTGAGAAACTGAGGATGAAA
  ACTGAAGAGGAGAACCGGGTTCACACGGAGATCGAAATGTTTCTTAAAAAACAGCAGCAGAAACTTGAGG
  AGAAGCTAGAGTTCTGGATGGAGAAATTTGACAAAGACACAGAAGCAAAGCAGAACGAGTTAAATGCTCT
  CAAGGCTGCCAAGGCCAGTGACCTGGTACACCTGCAAGACCTGGCAAAGATGATCCGGGAGTACGAGCAG
  GTCATTATTGAGGACCGGATAGAAAAGGAGAAGACCCGGAAGAAGCTGGAGCAGGATGACCTGGAGCTGA
  GGAGCATCGTGAAGCTCCAGGCCTGGTGGCGAGGGTCAGTGGTCCGGAAGGAAATTGGCAATTTCAAAAT
  GCCCAAGAAAGATAAAGATGACAGCAAAGACTCGAAAGGCAAGGAGAAGGAGAAGAGGAGAAAGAAGTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_178378
• Insert Size: 1260 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_178378.3, NP_848465.1
• RefSeq Size: 4027 bp
• RefSeq ORF: 1260 bp
• Locus ID: 69707
• UniProt ID: Q80W32
• Cytogenetics: 16 B3
• Gene Summary: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades (By similarity). Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility (PubMed:24362311, PubMed:24849454).[UniProtKB/Swiss-Prot Function]