Stx17 (NM_026343) Mouse Untagged Clone

CAT#: MC210614

Stx17 (untagged) - Mouse syntaxin 17 (Stx17), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Stx17
• Synonyms: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC210614 representing NM_026343
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTGAAGATGAGGAAAAGGTGAAGTTACGCAGGCTTGAGCCAGCGATACAGAAATTCACTAAGATCG
  TGATCCCAACAGACCTGGAGAGGCTAAGAAAACACCAGATAAACATCGAGAAGTATCAGCGGTGCAGAAT
  TTGGGACAAGTTGCACGAAGAGCACATCAACGCAGGGCGCACGGTTCAGCAACTGCGCTCCAATATCCGA
  GAAATGGAGAAGCTTTGCTTGAAAGTGCACAAGGATGATCTGGTCCTTTTGAAGCGAATGATAGATCCTG
  TCAAGGAAGCAGCAGCAACAGCTACGGCAGAGTTCCTCCAGCTCCACTTGGAATCTGTTGAAGAACTCAA
  GAAACAAGTCAACGATGAAGAATTACTTCAGCCTTCTCTGACCAGATCCACAACTGTTGATGGAGTGCTC
  CACACTGGGGAGGCTGAAGCTGCTTCTCAGAGTCTGACTCAGATATATGCCTTGCCTGAAATTCCTCAAG
  ACCAAAATGCTGCTGAGTCCTGGGAAACCTTAGAAGCGGACTTAATTGAGCTGAGCCATCTGGTCACTGA
  CATGTCCCTCCTAGTGAGTTCTCAGCAGGAGAAGATTGACAGCATTGCAGACCATGTCAACAGTGCCGCT
  GTGAATGTTGAAGAGGGAACCAAAAACTTGCAGAAGGCTGCAAAATACAAGCTGGCAGCTCTGCCTGTGG
  CAGGTGCACTCATCGGAGGAGTGGTAGGGGGTCCCATCGGCCTCCTCGCAGGCTTCAAAGTGGCAGGAAT
  TGCAGCTGCACTTGGTGGTGGGGTGTTAGGCTTCACAGGTGGAAAATTGATACAAAGAAGGAAACAGAAA
  ATGATGGAGAAGCTCACTTCCAGCTGTCCAGATCTCCCTAGCCAAAGTGACAAAAAACGCAGTTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_026343
• Insert Size: 906 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_026343.2, NP_080619.2
• RefSeq Size: 5777 bp
• RefSeq ORF: 906 bp
• Locus ID: 67727
• UniProt ID: Q9D0I4
• Cytogenetics: 4 B1
• Gene Summary: SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. May also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi (By similarity).[UniProtKB/Swiss-Prot Function]