Cadm1 (NM_207676) Mouse Untagged Clone

CAT#: MC209994

Cadm1 (untagged) - Mouse cell adhesion molecule 1 (Cadm1), transcript variant 2, (10ug)


  "NM_207676" in other vectors (4)

Reconstitution Protocol

USD 732.00

5 Weeks*

Size
    • 10 ug

Product Images

Frequently bought together (3)
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Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

USD 59.00

Other products for "Cadm1"

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cadm1
Synonyms 2900073G06Rik; 3100001I08Rik; AI987920; Bl2; Igsf4; Igsf4a; Necl2; RA175; RA175A; RA175B; RA175C
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC209994 representing NM_207676
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCGAGTGCTGTGCTGCCGAGCGGATCCCAGTGTGCGGCGGCAGCGGCTGTGGCGGCGGCGGCGGCGC
CTCCAGGGCTCCGGCTCCGGCTCCTGCTGTTGCTCCTTTCGGCCGCGGCACTGATCCCCACAGGTGATGG
ACAGAATCTGTTTACTAAAGACGTGACAGTGATTGAAGGAGAAGTGGCAACCATCAGCTGCCAGGTCAAT
AAGAGTGACGACTCAGTGATCCAGCTCCTGAACCCCAACAGGCAGACCATTTACTTCAGGGACTTCAGGC
CTTTGAAGGACAGCAGGTTTCAGCTGCTGAATTTTTCTAGCAGTGAACTCAAAGTGTCACTGACGAATGT
CTCAATCTCGGATGAAGGGAGATACTTCTGCCAGCTCTACACGGACCCCCCACAGGAGAGTTACACCACC
ATCACAGTCCTGGTTCCTCCACGTAACTTGATGATCGATATCCAGAAAGACACGGCAGTTGAAGGGGAGG
AGATTGAAGTCAACTGTACTGCCATGGCCAGCAAGCCAGCGACGACCATCAGGTGGTTCAAAGGGAACAA
GGAACTCAAAGGCAAATCAGAGGTGGAGGAGTGGTCGGACATGTACACTGTGACCAGTCAGCTGATGCTG
AAGGTGCACAAGGAGGACGACGGGGTCCCGGTGATCTGCCAGGTGGAGCACCCTGCGGTCACTGGAAACC
TGCAGACCCAGCGCTATCTAGAAGTGCAGTATAAACCGCAAGTGCATATCCAGATGACTTACCCTCTGCA
AGGCCTAACCCGGGAAGGGGATGCATTTGAGTTAACGTGTGAAGCCATCGGGAAGCCCCAGCCTGTGATG
GTAACTTGGGTGAGAGTCGATGATGAAATGCCTCAACATGCCGTACTGTCTGGGCCAAACCTGTTCATCA
ATAACCTAAACAAAACAGATAACGGTACTTACCGCTGTGAGGCTTCCAACATAGTGGGAAAGGCTCATTC
GGACTATATGCTGTATGTATACGACACCACGGCGACGACAGAACCAGCAGTTCACGATTCTCGAGCAGGT
GAAGAGGGGACCATTGGGGCAGTGGACCACGCAGTGATTGGTGGCGTCGTAGCCGTGGTGGTGTTTGCCA
TGCTATGCTTGCTCATCATTCTGGGCCGCTATTTTGCCAGACATAAAGGTACATACTTCACTCATGAAGC
CAAAGGAGCCGATGACGCAGCAGACGCAGACACAGCTATAATCAATGCAGAAGGAGGACAGAACAACTCC
GAAGAAAAGAAAGAGTACTTCATCTAG


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_207676
Insert Size 1287 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_207676.2, NP_997559.1
RefSeq Size 4303 bp
RefSeq ORF 1287 bp
Locus ID 54725
UniProt ID Q8R5M8
Cytogenetics 9 A5.3
Gene Summary Mediates homophilic cell-cell adhesion in a Ca(2+)-independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and NECTIN3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. Acts as a synaptic cell adhesion molecule and plays a role in the formation of dendritic spines and in synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.