Sco1 (NM_001040026) Mouse Untagged Clone

CAT#: MC209919

Sco1 (untagged) - Mouse SCO cytochrome oxidase deficient homolog 1 (yeast) (Sco1), nuclear gene encoding mitochondrial protein, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sco1
• Synonyms: 2610001C07Rik; D11Bwg1310e
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209919 representing NM_001040026
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCAGCACTTGTACGCGCCGCAGTGGTGAGGTCGCAGTGTCGCCAGCTCTGGCGTCTGTTCCCTCGCG
  GCCATGGGCTCAGGGATGTGGCGGAGAGGCCGAGACCGGAGGAAGCGTGCTCCTGCCTGCGGAGCAGAGC
  CTTCAGCGCTGGGCCGCCACCGCCGGGGGCCGGTCCGGAGCCCAAGGGCGGTCAAGCCGGGTCTCACCGC
  CCGAAGCCTGGGCCTGTTTCTTGGAAGTCTTTAGCTCTCACCTTTGCCATTGGAGGCTCTTTATTGGCTG
  GAATGAAGTACTTCAAGAAAGAAAAGATAGAAAAGCTGGAGAAACAACGGCATCGCAGCATTGGGAAGCC
  TTTACTAGGGGGGCCATTTTCCCTTACAACTCACAATGGAGAGCCCAAAACCGACAAGGACTACCTGGGT
  CAATGGGTATTGATTTATTTTGGCTTCACTCATTGCCCTGATATCTGTCCAGAAGAACTAGAAAAAATGA
  TTGAAGTCGTGGAGGAGATAGACAGTATTCCATCCCTGCCAAATTTAACTCCACTTTTCATCACCATTGA
  CCCAGAAAGGGACACCAAAGAAGCCATTGCGACTTATGTGAAAGAATTTTCTCCCAAATTGGTTGGTTTG
  ACTGGCACAAAAGAAGAGATTGATGGAGTGGCCAGAGCATACAGGGTGTATTACAGCCCTGGCCCGAAGG
  ATGAGGATGAAGACTACATAGTGGATCATACAATAATAATGTACTTGATTGGACCAGATGGAGAATTTCT
  TGATTATTTTGGACAAAACAAGAAGAAGGCAGAAATAGCCGGCTCAATTGCTGCACACATGAGGTCACAC
  ATGAAGAAGAGGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001040026
• Insert Size: 855 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001040026.1, NP_001035115.1
• RefSeq Size: 4280 bp
• RefSeq ORF: 855 bp
• Locus ID: 52892
• UniProt ID: Q5SUC9
• Cytogenetics: 11 40.59 cM
• Gene Summary: Copper metallochaperone essential for the maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Not required for the synthesis of MT-CO2/COX2 but plays a crucial role in stabilizing MT-CO2/COX2 during its subsequent maturation. Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (By similarity). Plays an important role in the regulation of copper homeostasis by controlling the abundance and cell membrane localization of copper transporter CTR1 (PubMed:25683716, PubMed:28973536).[UniProtKB/Swiss-Prot Function]