Foxe3 (NM_015758) Mouse Untagged Clone

CAT#: MC209836

Foxe3 (untagged) - Mouse forkhead box E3 (Foxe3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Foxe3
• Synonyms: dyl; FREAC8; rct
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209836 representing NM_015758
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGATGCGCAAGTCGCTTTCTCGGGCTTCCCGGCCTTGCCCTCGCTCACGCCGTCCGGGCCGCAGCTGC
  CGACGCTGGCGGGAGCCGAACCGGGGCGCGAACCGGAGGAAGTGGTGGGCGGTGGGGACGCCGAGCCCAC
  GGCCGTGCCTGGCCCGGGGAAGCGACGGCGGCGGCCACTACAGCGTGGGAAGCCGCCCTACTCATACATC
  GCGCTCATTGCCATGGCCCTGGCGCACGCTCCCGGCCGCCGTCTAACGCTGGCAGCCATCTACCGCTTCA
  TCACCGAGCGCTTCGCCTTCTACCGCGACAGCCCGCGCAAGTGGCAGAACAGCATCCGCCACAACCTCAC
  CCTCAACGACTGTTTCGTCAAGGTGCCGCGCGAGCCGGGCAATCCGGGCAAGGGCAACTACTGGACGCTC
  GATCCCGCGGCCGCTGACATGTTCGACAACGGTAGCTTCCTGCGGCGCCGCAAGCGCTTCAAGCGCGCTG
  AGCTGCCCGCACCGCCGCCGCCGCCGCCGCCCTTCCCCTATGCGCCCTTCCCGCCCCCGCCAGCACCCGC
  GTCCGCTCCGCCCGCGCGCCTCTTCCGCCTGGACAGCCTGTTGGGCTTGCAGCCTGAGCCGCCGGGACCC
  GTGGCGCCCGAGCCGCCTTGCTGCGCCGCGCCCGACGCCGCCTTCCCGCCCTGTGCCGCCGCAGCCTCGC
  CGCCGCTCTACTCGCCAGCGTCCGAGCGCCTGGGGTTACCCGCGCCGCTGCCCGCCCAGCCTCTCCTGGC
  CTTGGCGGGATCGGCCGGCGCGCTCGGGCCGCTCGGAGCCGGGGAAGCCTACCTGAGACAGCCGGGCTTC
  GCGCCGGGGCTGGAGCGCTACCTGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_015758
• Insert Size: 867 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015758.2, NP_056573.1
• RefSeq Size: 867 bp
• RefSeq ORF: 867 bp
• Locus ID: 30923
• UniProt ID: Q9QY14
• Cytogenetics: 4 D1
• Gene Summary: Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:10652278, PubMed:10890982). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (PubMed:16199865). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (PubMed:10652278). Is required for morphogenesis and differentiation of the anterior segment of the eye (PubMed:17064680). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (By similarity).[UniProtKB/Swiss-Prot Function]