Sla (NM_001029841) Mouse Untagged Clone

CAT#: MC209409

Sla (untagged) - Mouse src-like adaptor (Sla), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sla
• Synonyms: Slap; Slap-1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209409 representing NM_001029841
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTCTGCAGGCTTCGAGTACCTTCCACAGCTCAAGGAGAGAAAGAGATGGGGAATAGCATGAAATCCA
  CATCTCCACCTTCGGAGAGGCCGTTATCCAGCAGTGAGGGACTTGAAAGTGACTTCCTGGCTGTGCTGAC
  TGACTACCCATCTCCTGACATTAGCCCCCCAATATTCCGGAGAGGAGAGAAACTGCGTGTAATTTCTGAT
  GAAGGGGGCTGGTGGAAAGCCATTTCTCTCAGCACTGGCCGGGAAAGTTATATTCCAGGGATATGTGTGG
  CCAGAGTGTACCATGGCTGGCTGTTTGAAGGACTGGGCAGGGACAAGGCTGAGGAACTGCTGCAGCTGCC
  AGATACAAAGATTGGTAGCTTCATGATTCGAGAGAGTGAAACAAAGAAAGGTTTCTATTCGCTGTCTGTG
  AGACACAGGCAGGTGAAGCATTATCGAATCTTCCGTCTTCCCAACAACTGGTACTACATCTCACCAAGGC
  TCACCTTCCAATGCCTGGAGGACCTGGTGACTCATTATTCTGAAGTGGCTGATGGTCTATGCTGTGTGCT
  CACCACACCCTGTCTGGCACAGAACATACCTGCTCCAACATCCCACCCATCACCTTGCACCAGCCCTGGT
  TCACCTGTCACCTTGCGCCAGAAGACCTTTGACTGGAAGAGGGTATCCAGATTGCAAGAAGGTTCAGAGG
  GAGCAGAGAACCCACTCAGAGTGGACGAATCCCTTTTCAGCTATGGTCTTCGGGAAAGCATTGCCTCTTA
  CCTGTCCCTGACAGGGGATGACAGCAGCTCCTTCGACCGGAAGAAGAAGAGTCTCTCCCTAATGTACACT
  GGCAGCAAACGCAAGAGTTCCTTTTTTTCAGCACCCCAGTACTTTGAAGATTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_001029841
• Insert Size: 894 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001029841.4, NP_001025012.1
• RefSeq Size: 2866 bp
• RefSeq ORF: 894 bp
• Locus ID: 20491
• UniProt ID: Q60898
• Cytogenetics: 15 29.3 cM
• Gene Summary: Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longer isoform (a).