Sfrp4 (NM_016687) Mouse Untagged Clone

CAT#: MC209381

Sfrp4 (untagged) - Mouse secreted frizzled-related protein 4 (Sfrp4), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sfrp4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC209381 representing NM_016687
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCTCCGCTCCATCCTGGTGGCGTTATGCCTGTGGCTGCGCCTGGCGCTGGGAGTTCGCGGAGCGCCCT
  GCGAAGCTGTGCGCATCCCCATGTGCAGGCACATGCCCTGGAACATCACCCGGATGCCCAACCACCTGCA
  CCACAGCACTCAGGAGAACGCCATCCTGGCCATCGAACAGTATGAAGAGCTAGTGGACGTGAACTGCAGC
  TCTGTGCTGCGCTTCTTCCTTTGTGCCATGTACGCACCCATCTGTACCCTGGAGTTCCTGCACGATCCCA
  TCAAGCCCTGCAAGTCTGTGTGCCAGCGCGCACGTGACGACTGCGAGCCCCTCATGAAGATGTATAACCA
  CAGCTGGCCAGAGAGCCTGGCCTGCGATGAGCTGCCGGTCTATGACCGTGGAGTTTGTATCTCTCCAGAG
  GCAATAGTCACTGACCTTCCAGAAGATGTGAAGTGGATAGACATCACACCAGATATGATGGTGCAAGAAA
  GGTCCTTTGATGCTGACTGTAAACGTCTGAGCCCTGATCGGTGCAAGTGCAAAAAGGTGAAGCCGACCCT
  GGCAACATACCTGAGCAAAAACTACAGCTATGTTATTCATGCCAAAATAAAAGCCGTCCAGAGGAGTGGT
  TGCAATGAGGTCACAACTGTGGTAGATGTAAAAGAGATCTTCAAGTCTTTGTCACCTATCCCTCGAACAC
  AAGTCCCTCTCATCACCAATTCCTCCTGCCAGTGTCCACATATCCTGCCCCATCAAGATGTCCTAATCAT
  GTGTTATGAGTGGCGTTCAAGGATGATGCTTCTTGAAAATTGCTTAGTTGAAAAGTGGAGAGATCAACTC
  AGTAGAAGGTCCATACAGTGGGAAGAGAGGCTTCAGGAACAGCAGAGAACAATTCAGGACAAGAAGCAGA
  TAGCCAGCCGCACCAGTCGCACCAGTCGCAGTAACCCCCCAAAGTCAAAGGGAAGGCCACCTGCTCCCAA
  ACCTGCCAGTCCTAAGAAGAACATCAAAGCTAGAAGTGCCCCCAAAAAGTCAAACCTGAAGAAAAGCGCA
  AGCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_016687
• Insert Size: 1056 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016687.3, NP_057896.1
• RefSeq Size: 1780 bp
• RefSeq ORF: 1056 bp
• Locus ID: 20379
• UniProt ID: Q9Z1N6
• Cytogenetics: 13 6.99 cM
• Gene Summary: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types (PubMed:27355534). SFRP4 plays a role in bone morphogenesis (PubMed:27355534). May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity).[UniProtKB/Swiss-Prot Function]