Bloc1s4 (NM_133724) Mouse Untagged Clone

CAT#: MC207848

Bloc1s4 (untagged) - Mouse cappuccino (Cno), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Bloc1s4
• Synonyms: 2610101N07Rik; Blos4; Cno
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC207848 representing NM_133724
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGAGGAAGGACCCGCCGTCGGAACCCTGTCTCGAGAGGTCTCTACCGAGGAGGCCGAGCCGTTGGGCG
  CCGCGTGGAGCGGGGACAGCGGCCACGTCTCGCAGAGCCACAGCAGCGCGTCCGGGCCGTGGGACGATGA
  CGGCCCCGAGGACGCGCCGGGCCGCGACCTGCCGCTGCTGCGCCGCGCCGCCTCGGGCTACGCCTCCAGC
  CTGCTGCCCAGCGCGGGACCGAGGCCAGAGGTGGAGGCGCTGGACGCCAGCCTGGAGGAGCTGCTGGCCA
  AGGTGGACGAGTTCGTGGGCATGCTGGACATGATCCGCGGGGACTCGTCGCATGTGGTGGGCGAGGGCGT
  GCCCCGGATCCACGCTAAGGCGGCCGAGATGAGGCGCATCTACGGCCGGATCGACAAGCTGGAGGCCTTC
  GTGCGGATGATCGGGAGCAGCGTGGCCAGGATGGAGGAGCAGGTCGCCAAGGCCGAAGCCGAGCTGGGGA
  CCTTCCCGCGGGCCTTCCGGAGGCTGCTGCATACCATCAGCGTCCCCGCTCTCTTCAGGTCGGCGCCCAG
  CGGGCCCCAGCGCGCGGCGTACGAGCCGCCAGTCCTGTTTCGGACCGAGGACCACTTCCCTGGCTGCGGT
  GACAGACCGCAGCTCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_133724
• Insert Size: 648 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_133724.3, NP_598485.1
• RefSeq Size: 1306 bp
• RefSeq ORF: 648 bp
• Locus ID: 117197
• UniProt ID: Q8VED2
• Cytogenetics: 5 B3
• Gene Summary: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.[UniProtKB/Swiss-Prot Function]