Rd3 (NM_023727) Mouse Untagged Clone
CAT#: MC207737
Rd3 (untagged) - Mouse retinal degeneration 3 (Rd3), transcript variant 1, (10ug)
"NM_023727" in other vectors (4)
Product Images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Rd3 |
Synonyms | 3322402L07Rik; rd-3 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC207737 representing NM_023727
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCCCTCATCCCGTGGCTCCGGTGGAACGACACCCCTCCCCGGCTCTCGGCCCGGACCCCGGCCGAGA TGGTGCTGGAGACGCTCATGATGGAGCTGGCTGGGCAGATGAGAGAGGTGGAGCGACAACAGAGGGAGCG TCGCAGCGCAGTCAGGAAGATCTGCACTGGTGTGGACTACAGCTGGTTGGCAAACACGCCCAGGCCCACC TATGACATCAGCCCTGGTGAGCGGCTGCAGTTGGAGGATGTATGTGCCAAGATCCACCCATCCTACTGTG GGCCTGCCATCCTCAGGTTCAGGCAGCTGCTGGCTGAACGAGAGCCCGAGGTGCAGGAGGTGGCGCGGCT GTTCCGCTCCGTGTTGCAGGAGGCCCTGGAGAAGATGAAGCAGGAGGAGGAGGCCCATAAGCTGACACGT CAGTGGAGCTTGAGGCCCCGCGGCAGCCTGTCGTCCTTCAAGACCCGCGCTCGCATCGCACCCTTTGCCA GTGACATCCGAACCATCTCGGAGGATGTGGAGCGCGATGCGCCACCCCCGCCGCGCACCTGGAGCATGCC GGAGTTCAGGGCGCCCCAGGCCGACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_023727 |
Insert Size | 588 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_023727.4, NP_076216.3 |
RefSeq Size | 3723 bp |
RefSeq ORF | 588 bp |
Locus ID | 74023 |
UniProt ID | Q8BRE0 |
Cytogenetics | 1 97.09 cM |
Gene Summary | Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors (PubMed:21078983, PubMed:27471269). Inhibits the basal catalytic activity and the GCAP-stimulated activity of GUCY2E and GUCY2F, two retinal guanylyl cyclases involved in the production of cGMP in photoreceptors (PubMed:27471269). Involved in the transport of GUCY2E and GUCY2F to their target sites in the photoreceptor outer segment (PubMed:21078983). Up-regulates the activity of GUK1, a kinase that plays also an essential role for recycling GMP and indirectly, cGMP (By similarity). Plays an important role for the survival of rods and cones in the retina (PubMed:8486383, PubMed:17186464).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer isoform (1). |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG201915 | Rd3 (tGFP-tagged) - Mouse RIKEN cDNA 3322402L07 gene (3322402L07Rik) |
USD 500.00 |
|
MR201915 | Rd3 (Myc-DDK-tagged) - Mouse retinal degeneration 3 (Rd3), transcript variant 1 |
USD 300.00 |
|
MR201915L3 | Lenti ORF clone of Rd3 (Myc-DDK-tagged) - Mouse retinal degeneration 3 (Rd3), transcript variant 1 |
USD 600.00 |
|
MR201915L4 | Lenti ORF clone of Rd3 (mGFP-tagged) - Mouse retinal degeneration 3 (Rd3), transcript variant 1 |
USD 600.00 |
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