Ing2 (NM_023503) Mouse Untagged Clone

CAT#: MC207679

Ing2 (untagged) - Mouse inhibitor of growth family, member 2 (Ing2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ing2
• Synonyms: 2810011M06Rik; Ing1l; Ing2b; P33ING2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC207679 representing NM_023503
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTTAGGGCAGCAGCAGCAGCAGCAGCTGTACTCGTCGGCCGCGCTCCTGACCGGAGAGCGGAGCCGGC
  TGCTCTCCTGCTACGTGCAGGACTACCTGGAGTGTGTGGAGTCGCTGCCCCACGACATGCAGAGGAACGT
  GTCGGTGCTGCGGGAGCTGGACAACAAATACCAAGAAACGTTAAAGGAAATTGATGATGTCTATGAAAAA
  TATAAGAAAGAAGATGATTCCAACCAGAAAAAACGCCTACAGCAGCATCTCCAGAGAGCGTTAATCAATA
  GCCAAGAATTGGGAGATGAAAAAATTCAGATTGTCACCCAGATGCTCGAATTGGTGGAGAACCGAGCGAG
  ACAAATGGAGCTGCATTCACAGTGTTTCCAGGATCCTGCTGAAAGTGAGCGAGCCTCAGACAAGTCGAAG
  ATGGATTCCAGTCAACCGGAAAGATCTTCTAGAAGACCTCGAAGACAGAGGACCAGTGAGAGCCGTGACT
  TATGTCACATGACAAACGGGATTGACGACTGTGATGATCAACCACCGAAAGAAAAGAGATCCAAGTCCGC
  CAAGAAGAAGAAGCGCTCCAAGGCCAAGCAGGAGAGGGAGGCATCCCCTGTCGAGTTTGCCATCGATCCC
  AATGAGCCCACCTACTGCTTGTGTAACCAAGTGTCCTACGGGGAGATGATAGGCTGTGACAATGAACAGT
  GTCCCATTGAATGGTTTCACTTTTCATGTGTTTCACTCACCTATAAACCCAAGGGGAAATGGTATTGCCC
  AAAGTGTAGGGGAGACAATGAGAAAACCATGGACAAAAGTACCGAAAAGACAAAAAAGGAGAGAAGAGCG
  AGGTAG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_023503
• Insert Size: 846 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_023503.3, NP_075992.2
• RefSeq Size: 2813 bp
• RefSeq ORF: 846 bp
• Locus ID: 69260
• UniProt ID: Q9ESK4
• Cytogenetics: 8 B1.1
• Gene Summary: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs) (By similarity).[UniProtKB/Swiss-Prot Function]