Commd5 (NM_025536) Mouse Untagged Clone

CAT#: MC207581

Commd5 (untagged) - Mouse COMM domain containing 5 (Commd5), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Commd5
• Synonyms: 2310065H03Rik; AI854466; D15Ertd81e; Hcarg
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC207581 representing NM_025536
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGTCTGCGTTGGGGGCTGCGGCTCCATACTTACACCATCCAACTGACAGTCACAGCGGCCGGGTCAGTT
  TCCTGGGTTCCCAGCCCTCTGCAGAAGTGACGGCAGTGGCCCAGCTCTTGAAGGACTTAGACAGGAGCAC
  CTTCAGAAAGTTGTTGAAACTCGTAGTCGGGGCCCTCCATGGGAAAGACTGCAGAGAGGCCGTGCAGCAC
  CTTGGTGCCAGCGCCAACCTGTCAGAGGAGCGTCTGGCCGTCCTGCTGGCGGGCACACACACCCTGCTCC
  AGCAGGCTCTCCGGCTGCCCCCTGCCAGTCTGAAACCAGATGCCTTCCAGGACGAACTCCAGGAACTTGG
  CATTCCCCAAGATATGATTGGAGATCTGGCCAGTTTGGCATTTGGGAGTCAACGCCCTCTTCTCGACTCT
  GTAGCCCAGCAGCAGGGATCCTCGCTGCCTCGTGTGTCGAATTTCCGGTGGCGGGTGGATGTGGCCATCT
  CAACCAGTGCTCAGTCCCGCTCCCTGCAACCGAGTGTTCTCATGCAGCTGAAGCTCACAGATGGATCGGC
  ACACCGCTTCGAGGTGCCCATAGCCAAATTCCAGGAGCTGCGCTACAGCGTGGCGTTGGTCCTTAAGGAG
  ATGGCAGAGCTGGAGAGAAAGTGTGAGCGCAAACTGCAGGACTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_025536
• Insert Size: 675 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_025536.2, NP_079812.1
• RefSeq Size: 998 bp
• RefSeq ORF: 675 bp
• Locus ID: 66398
• UniProt ID: Q8R395
• Cytogenetics: 15 36.28 cM
• Gene Summary: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.[UniProtKB/Swiss-Prot Function]