Cradd (NM_009950) Mouse Untagged Clone

CAT#: MC207250

Cradd (untagged) - Mouse CASP2 and RIPK1 domain containing adaptor with death domain (Cradd), (10ug)


  "NM_009950" in other vectors (4)

Reconstitution Protocol

USD 330.00

3 Weeks*

Size
    • 10 ug

Product Images

Frequently bought together (3)
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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cradd
Synonyms RAIDD
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC207250 representing NM_009950
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAAGCCAGAGACAAGCAGGTACTCCGCTCCCTGCGTCTGGAGCTGGGTGCCGAGGTACTGGTGGAAG
GACTGGTTCTTCAGTACCTTTACCAGGAAGGAATTTTGACAGAAAACCACATTCAAGAAATCAAAGCTCA
AACCACAGGCCTCCGGAAGACAATGCTGTTGCTGGACATCCTGCCTTCCAGGGGCCCCAAAGCTTTTGAC
ACCTTCCTCGATTCCCTCCAGGAATTTCCCTGGGTAAGAGAGAAGCTGGAGAAGGCGAGAGAGGAAGTCA
CAGCCGAGCTGCCTACAGGTGACTGGATGGCCGGAATCCCCTCACACATCCTCAGCAGCTCGCCATCAGA
CCAGCAGATTAACCAGCTGGCTCAGAGGCTAGGCCCGGAGTGGGAGCCCGTGGTCCTGTCTCTGGGACTG
TCCCAGACCGACATCTACCGCTGCAAGGCCAACCATCCCCACAACGTGCATTCGCAGGTGGTGGAGGCCT
TTGTCCGCTGGCGCCAGCGTTTTGGGAAGCAGGCCACCTTCCTAAGCTTACACAAGGGCCTCCAGGCAGT
GGAGGCTGATCCCTCCCTGCTCCAGCACATGCTGGAGTGA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_009950
Insert Size 600 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_009950.2, NP_034080.1
RefSeq Size 1650 bp
RefSeq ORF 600 bp
Locus ID 12905
UniProt ID O88843
Cytogenetics 10 49.26 cM
Gene Summary Adapter protein that associates with PIDD1 and the caspase CASP2 to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis. Also recruits CASP2 to the TNFR-1 signaling complex through its interaction with RIPK1 and TRADD and may play a role in the tumor necrosis factor-mediated signaling pathway.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, 3, and 4 encode the same protein.

Other Versions

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.