Hdac7a (BC057332) Mouse Untagged Clone

CAT#: MC206792

Hdac7a (untagged) - Mouse histone deacetylase 7A (cDNA clone MGC:66951 IMAGE:6826982), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Hdac7a
• Synonyms: 5830434K02Rik; HD7; HD7a; Hdac7a; mFLJ00062
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC057332
  CGCCAGGCTGTGTGCTGCTGAGCGAAGCCCGGGTGGTGTGTCCCAGGGCCGCCAGCGCCGGCCCCCTCCC TCCCCTCCCCCTTGGCCCGCTCTCAGACTCAGATAAAGCATTTCCTTCCATTGTCATCCTACCCGGCCGG CCAGGCTGCCAGGGCCCTCCCCCTCCCGGCCCCCTCCCTTCCTCTCGCCGTCTCACAGTCGCTCTGCAGC CTCCGGCGACCGGGGGGATGTGAGGCCGGCGCCCCGGCCCCCCGCCCGCCATGAGCCCCCGGCTCTGAGG GCCCCGGCCCCTGGATGCACAGCCCCGGCGCGGGCTGCCCTGCCCTCCAGCCAGACACACCAGGCTCTCA GCCCCAACCCATGGACCTGCGGGTGGGCCAGCGGCCCACGGTGGAGCCCCCACCAGAGCCTGCGCTGCTG ACCCTGCAACACCCCCAACGCCTGCACCGCCATCTCTTCCTGGCAGGCTTACACCAGCAACAGCGCTCAG CCGAGCCCATGAGGCTCTCCATGGACCCACCAATGCCGGAGCTGCAGGGGGGACAGCAGGAGCAAGAACT TCGGCAACTTCTCAATAAAGACAAGAGCAAGCGAAGTGCCGTAGCCAGCAGTGTGGTCAAGCAGAAGCTG GCTGAAGTGATCCTGAAGAAACAGCAGGCAGCCCTTGAGAGAACAGTCCATCCCAGCAGCCCCAGTATTC CCTACAGAACTCTTGAGCCCTTGGACACAGAGGGTGCTGCCCGCTCCGTGCTTAGCAGCTTCCTGCCTCC TGTTCCCAGCCTGCCCACTGAACCCCCGGAACACTTTCCCTTGCGTAAAACAGTGTCTGAACCCAACCTG AAGTTGCGCTACAAACCCAAGAAATCCCTGGAGAGACGCAAGAATCCCCTGCTCAGGAAGGAGAGTGCCC CGCCCAGCCTTCGGAGGAGGCCTGCCGAGACCCTTGGAGATTCCTCCCCCAGTAGTAGCAGCACACCCGC GTCAGGGTGCAGCTCCCCTAATGACAGCGAGCATGGCCCTAACCCTGCCCTAGGCTCAGAGGCTGATGGT GACCGCAGGACCCATTCAACTTTAGGCCCTCGGGGTCCTGTACTGGGGAACCCCCATGCTCCCCTCTTCC TGCACCACGGTCTGGAGCCAGAGGCTGGGGGCACCTTACCCTCTCGCCTGCAACCCATTCTCCTGCTGGA CCCCTCAGTCTCTCATGCCCCACTGTGGACTGTGCCTGGCCTTGGGCCCTTGCCCTTCCACTTTGCCCAG CCCTTACTGACCACCGAGCGGCTCTCTGGGTCAGGCCTCCATCGACCACTTAACCGGACCCGCTCAGAGC CCCTGCCCCCCAGCGCCACAGCCTCCCCTCTGCTGGCCCCCCTGCAGCCCCGCCAGGATCGGCTCAAACC TCACGTCCAGCTGATCAAGCCAGCCATCTCCCCTCCCCAGAGGCCTGCCAAGCCCAGTGAGAAGCCCCGA CTGCGACAGATACCCTCGGCTGAGGACCTAGAGACAGATGGTGGGGGAGTGGGACCTATGGCGAATGATG GCCTGGAACATAGGGAGTCAGGCCGTGGGCCTCCTGAGGGCAGAGGCTCCATTTCTCTGCAGCAGCATCA ACAGGTGCCACCCTGGGAGCAGCAGCATCTAGCCGGGCGGCTCTCTCAGGGAAGCCCCGGGGACTCCGTG CTGATACCTCTGGCCCAGGTTGGACACCGGCCCCTGTCCAGAACCCAGTCTTCCCCAGCAGCACCTGTCT CCCTGCTGAGCCCAGAGCCCACCTGTCAGACCCAAGTCCTCAACAGCTCAGAGACACCTGCTACAGGGCT GGTCTATGACTCGGTGATGCTGAAACACCAATGTTCCTGTGGAGACAACAGCAAGCATCCCGAGCATGCA GGCCGCATCCAGAGCATCTGGTCCCGGCTGCAGGAACGGGGTCTCCGCAGCCAGTGTGAGTGTCTCCGAG GCCGAAAGGCTTCCCTAGAGGAGCTGCAGTCAGTCCACTCTGAACGGCACGTGCTCCTCTACGGCACGAA CCCACTCAGCCGCCTCAAACTGGATAACGGGAAGCTTACAGGACTCCTGGCACAGCGGACGTTTGTGATG CTACCCTGTGGCGGGGTTGGGGTCGATACTGACACCATCTGGAACGAGCTGCATTCCTCCAATGCAGCCC GCTGGGCTGCGGGCAGTGTCACCGACCTTGCCTTCAAAGTAGCTTCCCGAGAGCTGAAGAATGGCTTTGC TGTGGTGCGACCCCCGGGACACCATGCAGATCATTCTACAGCCATGGGCTTCTGCTTCTTCAACTCCGTG GCCATCGCCTGCCGACAGCTACAGCAACACGGCAAAGCCAGCAAGATCCTCATTGTTGACTGGGATGTTC ACCATGGCAACGGCACACAGCAGACTTTCTACCAGGACCCCAGTGTGCTCTACATTTCCCTTCATCGCCA TGACGACGGCAACTTCTTCCCAGGCAGTGGGGCCGTGGATGAGGTGGGAACTGGCAGTGGCGAGGGCTTC AATGTCAACGTGGCTTGGGCTGGGGGCTTGGATCCACCCATGGGGGATCCTGAGTACCTGGCTGCTTTCA GGATAGTGGTGATGCCCATTGCCCGAGAGTTTGCTCCAGACCTGGTCCTGGTGTCTGCTGGGTTTGATGC TGCGGAGGGTCACCCAGCCCCGCTGGGTGGCTACCATGTTTCTGCCAAATGTTTTGGGTACATGACGCAG CAGTTGATGAACTTGGCAGGAGGCGCCGTGGTGTTGGCCTTAGAGGGTGGACATGACCTCACGGCCATCT GTGATGCCTCGGAGGCCTGTGTAGCTGCTCTTCTGGGCAACAAGGTGGACCCCCTTTCAGAAGAAAGCTG GAAACAGAAACCCAACCTCAGTGCCATCCGCTCGCTGGAAGCTGTGGTCAGGGTGCACAGGAAATACTGG GGCTGCATGCAGCGCTTGGCCTCCTGTCCAGACTCCTGGCTACCCAGAGTGCCGGGAGCTGATGCAGAAG TGGAAGCCGTGACCGCGCTGGCATCCCTTTCTGTGGGCATCCTGGCTGAAGACAGGCCCTCGGAGCGGCT GGTGGAAGAGGAAGAACCCATGAACCTCTAGGGTTTCAGAACAGATCGCGCTTCAAATGTGGCTCTCCTC GTCTCTGATGTCAGCCCTGGTCCTGGGTCTTCAGAGATCCTCTGGGCAGGTAGTCAGGTCCAGAGCACAG CCTACCCTGACGGCTATCCCAAGGAACTTGAGAAGACCATGGGATCTGGGTAGGGGACCAGGGAGGACTC TGGGAGGAAGCAGGTTGGGCACTAGGGCACAGCTGGGCTCTTCCAGAACAGATTAGGCCGTCTGGTGTCC ACACCCCTAGCTGTGGTCTCCATCCCTCCCTCAGGACTGCACAGAGGGGGACTGGCTCAACTGGGCCACC CATAACCACTATTCTTAACTTGGCCTCGGCCAGGGTGGCCTTTCTCAGGTTCTGAAGGGCTAGGAGCTGG AGGAGCCAAGGGTCCCCTATTCCTGAGTACAGGAGAGTTTCCTCTCTCCTGTTTCCTCAAATGCCTTTCT GGTAGCTCTGGGCTCTGAGAGCCATTCTGAGCTGCTCTCTCCCTGTGAGTAGTAGTCACCTGCAAGTCTC CCATCAGTCACTGTCTCGCCAGAGGCCACCCTATGTGGACCATCTCAGTGCCCCGGTGCAGCAGACAGGT GCTCTCTGAGTCCTGTGTCTCCTAACCCAACGGTGCCAAACCTTCATCTCCCTTCAAAAGCACAACACAA TCCCAGGGATGCCTGGTCACTGTCCCCAGTATGAGCCTTCTGTTTCTGGGGTCCCTCCCACCCCTCAGCT CTGGCTGCTGCCCCACATAGGACTAGCTTGGCTGAGGGGAACAAGATGGGAGAGTAGACAGACATGGGGG AGGGGAGGCCACCCCAGAAGTCTTCGAGGCTTTTGAGGTTTAGGTCTGGGACCAAGAAAGAGTATTTGTG TGTATGTGTGTGTATGAGTGCGTGCAAGAGGGTATATGTGTGTGTGTCTTCCCACAACCCCACCGTACCT TGTCTATGTATGCATGTTTTTGTAAAAAAGAAAAAAGTGAAAAAAAAAAACAAACTTCTGAACAATAAAA AAAAAAAAAAAAAAAAA
• Restriction Sites: EcoRI-NotI
• ACCN: BC057332
• Insert Size: 2817 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC057332, AAH57332
• RefSeq Size: 4147 bp
• RefSeq ORF: 2817 bp
• Locus ID: 56233
• Cytogenetics: 15 F1
• Gene Summary: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Positively regulates the transcriptional repressor activity of FOXP3 (By similarity). Serves as a corepressor of RARA, causing its deacetylation and inhibition of RARE DNA element binding (By similarity). In association with RARA, plays a role in the repression of microRNA-10a and thereby in the inflammatory response (By similarity).[UniProtKB/Swiss-Prot Function]