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Gosr1 (BC008542) Mouse Untagged Clone

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SKU
MC206221
Gosr1 (untagged) - Mouse golgi SNAP receptor complex member 1 (cDNA clone MGC:7654 IMAGE:3495882), (10ug)
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  $300.00
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Gosr1
Synonyms GS28, GOSRI, GOS-28
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC008542
CAAAGATGGCGGCAGGAACCAGCAATTACTGGGAAGATCTCAGGAAACAAGCTCGGCAGCTGGAAAACGA ACTTGACCTGAAACTCGTTTCCTTCAGTAAACTCTGTACGAGCTACAGCCACAGCGGCTCACGGGATGGA GGACGCGATAGGTACAGTTCTGACACAACACCGCTATTAAATGGATCAAGCCAAGACAGAATGTTTGAGA CAATGGCAATTGAAATTGAACAGCTTTTGGCAAGGCTTACAGGAGTAAACGACAAAATGGCAGAGTACAC CCACAGTGCAGGGGTGCCCTCCCTGAATGCAGCCCTGATGCACACGCTGCAGCGACACAGAGACATTCTG CAGGATTATACACACGAATTTCATAAAACCAAAGCAAACTTTACGGCAATACGGGAAAGGGAGAATCTCA TGGGATCAGTACGGAAAGATATTGAGTCATATAAAAGCGGGTCTGGAGTAAACAACAGGAGAACGGAACT GTTTCTGAAAGAGCATGACCACCTTCGAAACTCTGATCGTCTGATAGAAGAAACAATAAGCATTGCTATG GCAACAAAAGAGAATATGACTTCCCAGAGAGGAATGCTCAAGTCAATTCACAGCAAGATGAACACTCTGG CCAACCGCTTTCCTGCCGTGAACAGCCTGATACAAAGGATCAACCTTAGGAAACGGCGTGACTCGCTCAT CCTTGGAGGTGTCATTGGCATCTGCACCATCCTGTTGCTGCTGTATGCGTTCCACTGAAAGCATAGCCCC AGGACTCTCTGCCCACCACCTTCATGGCCTGATCTGGACTGGGGAGCCTACCAAGGAGAAAGACCATCCC GGCCACGGGCGCCACCAGATGGATTCCAAACTGCACCTGTGGCTCTGACCTGGTCGGGCTGAGCTGAAGC CGAAGTTTTTCTGTGCTATCTTTTCTAATACACATTACTCTGTTTTTAATTTTAAAAACAACAAAAGGTT TCCGTTGCTGTGTCTCCCTAGGAGGTAAGCAGGCAGAAGCTGAGAAGCTGGGCTTCAGTGACTGGCGAGG CCAGATGATCAGCGGGCCTCGGAGCTGGACTCCTCGTAGCACCAGACTCTCTACATCCAAAGATGGCTTC ACTTTCAGCCACGAGATTGGATGTGAATAAAAGTAATTTTTGTCCTTTTATTTAACACTTGTGATGAGTA ATCAGCTGTCCTTTGCTGATACTCTGTGATCTGTATTCTATTCTGTGTCCCTAACTCTTAGCAGTCAAGA AAAATTCCATGTCCCACGGGTTCTGTGAGATGTTGGTAGGCCAGCTTCATGTTTGAGGTGGTCTGAAATG GAGAGTGCTGTAGAAAGGGCGTCTCGTCTCTGCGTCAGCTGTGAGCGCTGCGTCAGCTGTACCGCCGCCA ACACATCAGAATGGCAGACCTTGCCATTGCTTTATTATTTTTTCCACTGGGCTAATATTTGCTTGTACAT GATAAAATTGCATTTCCACTGACAGGCAATCAGCACCTGTCATTGCCCCTAGCGGTCCCATATCATGTGA AGCTTAATACTAGGAAGTGAGGGAGGGGACTTGGTTCTCAGTGAGGTCTGCTCATGAGCCACTGCAAGGA GACAGTGAGAGGGTGGCTCTCTGGCCTTCCTGTCTGTCAGTGTGGTGCCGCCTGGAGCAAGGGTAGCACT GTGACCTGATGTCACAGTATTCGTGCCCTGTGCAGATCTATCCCTTCCTCCTCTGTTGGCGCCTTCCTTC CTACTCCTAGGCCGCCGGATAACCACTGAGGGGGCCTGGGACTCCTGCCTGCACCTCTCTATTACTTTGG GCAGTGACAGAATTGTGAATGTTTCTCAAGGTTAGCCACTTCTCAGCATCTGTAAATTGGTAACTTGTCG TACTGAACTAGCGGATAGTGTAAAGACTCCAACATCTGTGCTCTGCTGGTCCTACCCTGGAGTGGCCTCC AGCACATTGTCCAGGGGCAGTGAGTGGATATTAGAGCTCTTCACCATTCTATGGTGGGGGACGGTGCCTC TGGGCCACCTTGATACACTTACTGCGCATGGACAGACTGACACCCAGTCTGGGACTGACTGACAGTTTTG ACATCCTGCTGTTGAAGTGTTAGTACATTCTAGGTATGAAAGGCATTTGATATATTTTTCTTAATTATGG GGTTTATTTTTCTAAATATGGGTTAATCAGCTTGTTGACTGGGCATGCCCTTAAAAGGAATTTAAATTTC CCTCTATAGACCTTAAAGAATCAGGGAAGTTCATTTGTTAAATTCTCCTTGAGAGAACAGAACTTCTCTT CCCTGACACTTCTATTATCTTTGATTTTTTTCAAAGGGCCTTGATTGGCATTTGTGCCTCAGCTAGACTT TATGGGACTTTGGTTGTTATATAGTGGGCATATATGAAATCTGAAGTATCGTAAATAAAGTTATTTATTT AAATATACAGCCAGTCTTTTCTACTGGTTTGATGACATGTTTCATTCACTAAAGCTGATGAGAAAGCGTA GGCTAGGACATGGTCCTGCTCCACTGCCAGCCGCCACCGCACAGCAGCTGGGCCGCCCCAGGACGCTGCA CTCAGATGAACAGATGGAATTATGTTGCTTGTCTTCTTTTTGAGAGTAGATCAGTTCTTTCAAGGAACGC TAGCTGTAGCGGCTGGGGTCCGACCTTCCATTGTGGTGCCGTGGAGGGAAGAGTGCCCCTCCCTTTCCAG TTCTGCCCTGTACAGGACCCCCTTGGAACCTCGGTTTTGTGTCATTCAATATTTTTTTCAAGTTCGTTTC TCCCATTTTGGGCTTACCCCAGTTATCAGGCTTAGGCATGGACAGGGAGGGATGTCTTGTCAGAGCCTGA GGTAAGATTTGTGACCCCAGTGAACTGTTGCTCCCCGGCCACAGTTTTTAACAGAATACCTTTTTTTAAA AATATATATTTTTAGTAACAGTTCAAAACTTCCCACTTCACAAAAAGATATGAAAAACGGGAATAAACAG CAGAAAATTCCAAGTGTATTTGTCTGCCCTGGCTTGAGAGGTCTCACTGTTTAGCTCCGGCTGGCCTTGA GTTCCTGCCTCGGCTTCCTGAGACCCTGGGACTGCTATCTGATGTATACCACCAACCCTGGCTCCAAACA GTACCTTCCTCCAGTTTCCCATGTGTCCCAGTGACTCAGTGAAGATGTGCAGTCCATTGCTACTGAGATC CACAAACCCATACCAAAGGATGCTCTGCCTCCTGCCCTGCTCACCTCTGCTTGTTCCCTTCCCCTTGATA CCAGCATTGACATTTATTGAGAATGTCTTTCTGCTTCTTCCTGGTACTCGGATCAGAAATGGGGACAGGT GAGGAAGAGCCACTCTAGAGGACACTTTTGTACTGGGACCCAGATAGCTGAGGGCCTCCATGCTGGTCGT GGATAAGTGAGTGGGAAGCAGAGTCATTGCTCTGCCGCCCTGTGAGCCCTGTGGAGTTGAGGCACCTTGG CCTTCACCACATCACTGTCCTGTCTTACTGCTGATGACCTCGGCCTGAGGGGGTGGCTTCTAAGAATGGG TCTAGCCTTTCCGACTTCTCTTTATCTTCTGTCTTTAACCAGGTAAGAGTTTTGGGATTCATTGAGCTTT TGAACTTGTTATATTAAGTGGTTGGGATGCATGGCCATACCCAGGTCATCTGTGGCAGATGCGGCAGAGG AAACAAACCTACCCAAATGACGGATTGTGCACCGTCCTTATTTTACCGTAGAGGGCATCCTTTGGCCTGA TCTCCAAAAGGATGCAGCATTTCCCACTGCGGGCCCCAAACTCATTCGTCCCCCTGAGTGCCCATATGTC CCTTTCTCAGAGAGAATGGGGGACGAGAAACAAGGTCTAAACGTGATAATCTGGTGAGAAGCTGGGAAAG TTGAGTCATGTCTTAAAGAATGTGTTTTTTTTTTTTTTTCAATCTGATCTAAAATCTTAGTACCAAAATA TTTGTACCACACCCTAGTAGCTCTCAGTGATGGGAAATCAGTTCTTACCATACTTTATTCCGATGGAAGA CGATTGACGCCTGGTGAAAAATGCCAATACAGATTTTTTTTTAATCTATTCTTTTCCAAATGCACTTTCT AATTTTTTGCTTTTAAAATAGAGACTTGGAACCAATATTATTGTATTTTTACTTAATTTTTGTTCTCATC TAAATGTGCATTTTCTGACTGTATAGAAGAAACTTTGTTATATAATTTAATAAATTAAATATCTAAATAA AAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN BC008542
Insert Size 753 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC008542, AAH08542
RefSeq Size 4283 bp
RefSeq ORF 753 bp
Locus ID 53334
Cytogenetics 11 B5
Summary Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi (By similarity).UniProtKB/Swiss-Prot Function
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