Slc8a2 (BC058704) Mouse Untagged Clone

CAT#: MC206174

Slc8a2 (untagged) - Mouse solute carrier family 8 (sodium/calcium exchanger), member 2 (cDNA clone MGC:76359 IMAGE:6838206), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Slc8a2
• Synonyms: Ncx2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058704
  CTCTCCTCCCTCCTCCCTGCTCTCCCTCAGTCCCCGGCTCCTCTCCCTCTTTCTCCCTTTTCTCCTCGGG CGGAGGCGCCCACCGCGGGGGCCCAGCGGGGACCGGCCCGGCCGCAAGGCAGGACCTCACCACCCCCAAT GGCTCCCTTGGCTTTGATGGGGGTTGTTCTCCTTCTGGGGGTACCCCACTGCTTGGGGGAAGCCACTCCG ACCCCTTCCCTACCGCCTCCCACAGCTAATGACAGCGATGCCAGCCCAGAAGGCTGCCAAGGTTCCTACC GCTGCCAACCAGGTGTGCTGCTGCCTGTGTGGGAACCCGAGGACCCATCGCTGGGCGACAAGGTTGCACG GGCCGTGGTGTACTTTGTGGCCATGGTCTACATGTTCCTGGGTGTGTCTATCATTGCCGATCGATTTATG GCATCCATTGAGGTCATCACATCCAAGGAGAAAGAGATCACCATCACCAAGGCAAATGGGGAGACCAGCG TGGGCACGGTGCGCATCTGGAACGAGACGGTGTCCAACCTTACACTCATGGCCCTGGGCTCCTCAGCGCC TGAGATTCTGTTGACTGTCATCGAGGTCTGTGGCCACAACTTCCAGGCCGGTGAGCTAGGCCCAGGCACC ATCGTGGGCAGTGCCGCCTTCAACATGTTTGTGGTCATTGCTGTTTGTGTGTATGTCATCCCGGCTGGCG AGAGCCGTAAGATCAAGCACCTGAGGGTCTTCTTTGTCACAGCCTCCTGGAGCATCTTTGCCTATGTCTG GCTTTATCTCATTCTAGCAGTTTTCTCCCCAGGTGTAGTCCAGGTGTGGGAGGCACTGCTCACACTGATC TTCTTCCCGGTGTGTGTGGTGTTTGCCTGGATGGCGGACAAGCGACTGCTCTTCTACAAGTACGTGTACA AGCGCTACCGCACCGACCCTCGCAGTGGAATCATCATCGGGGCAGAGGGAGACCCACCCAAGAGCATCGA GCTGGACGGCACATTCGTGGGCACTGAGGTCCCTGGCGAGCTGGGCGCATTGGGCACAGGTCCTGCTGAG GCGCGTGAACTAGATGCCAGCCGGCGTGAGGTCATCCAGATCCTTAAGGACTTGAAGCAGAAGCACCCGG ATAAGGACCTGGAGCAGCTGATGGGCATCGCCAAGTACTATGCACTGCTGCACCAGCAGAAGAGCCGCGC CTTCTACCGCATCCAGGCCACGCGGCTGATGACAGGTGCGGGCAATGTGCTGCGCAGACATGCTGCGGAT GCTGCCCGCAGGCCGGGAGCCACCGATGGTGCCCCCGATGATGAGGACGATGGTGCCAGTCGCATCTTCT TTGAGCCCAGCCTCTATCACTGCCTGGAAAACTGCGGGTCAGTGCTGCTGTCCGTGGCTTGCCAGGGCGG TGAGGGCAACAGCACCTTCTACGTGGACTACCGTACCGAGGACGGTTCTGCAAAGGCAGGCTCCGATTAT GAGTACAGCGAGGGCACGCTGGTGTTCAAGCCCGGGGAGACGCAGAAGGACCTGCGCATCGGGATCATCG ACGACGACATCTTCGAGGAGGATGAGCACTTCTTCGTGAGGCTGCTGAACCTGCGTGTGGGCGATGCTCA GGGCATGTTCGAGCCCGACGGCGGTGGGCGGCCCAAGGGGCGGCTGGTGGCGCCGCTGCTGGCCACTGTC ACCATCCTGGACGACGACCACGCGGGCATCTTCTCCTTCCAGGACCGCCTGCTGCATGTGAGCGAGTGCA TGGGCACTGTGGATGTGCGCGTGGTTCGCAGCTCGGGCGCCCGTGGCACTGTACGCCTCCCCTACCGCAC AGTGGACGGCACGGCCCGTGGCGGTGGTGTACATTACGAGGATGCTTGTGGAGAGCTGGAGTTCGGCGAT GATGAGACCATGAAAACTCTTCAGGTCAAGATAGTGGATGATGAAGAGTATGAGAAGAAGGACAACTTCT TCATTGAGCTGGGCCAGCCCCAGTGGCTTAAGCGAGGCATCTCAGCTCTGCTACTCAACCAAGGGAATGG AGACAAGAAGATAACTGCAGAGCAGGAGGAGGCCCAGAGGATAGCAGAGATGGGCAAGCCAGTTCTTGGG GAGAACAATCGCCTCGAGGTCATCATCGAGGAGTCTTATGACTTTAAGAACACGGTGGATAAACTCATAA AGAAAACGAACCTGGCCTTGGTGATTGGGACTCACTCATGGAGGGAGCAGTTTATAGAGGCAGTTACCGT AAGCGCAGGGGACGAGGAGGAGGATGAGGATGGACCTCGTGAGGAGCGGCTGCCGTCCTGCTTTGACTAC GTGATGCACTTCCTGACGGTATTCTGGAAAGTTCTATTCGCCTGCGTTCCACCCACGGAGTACTGCAATG GCTGGGCCTGCTTTGGTGTCTGCATCCTGGTCATTGGTGTGCTCACTGCCCTCATCGGAGACCTGGCCTC ACACTTTGGGTGCACCGTGGGCCTCAAGGACTCAGTCAACGCCGTGGTCTTCGTAGCCCTGGGCACCTCC ATCCCTGACACGTTCGCCAGCAAGGTGGCCGCGCTGCAGGACCAGTGTGCCGACGCGTCCATCGGTAACG TGACCGGCTCCAATGCGGTGAACGTGTTCCTGGGCCTGGGTGTGGCCTGGTCGGTGGCAGCGGTATACTG GGCGGTGCAGGGTCGCCCCTTCGAGGTGCGTGCAGGCACGCTGGCCTTCTCGGTCACGCTGTTCACCGTC TTCGCCTTCGTGTGCATCGCAGTGCTGTTGTACCGGCGCCGGCCGCAGATTGGCGGCGAGCTGGGCGGCC CGCGGGGACCCAAGCTGGCCACCACCGCTCTCTTCCTGGGCCTCTGGTTCCTCTACATTCTCTTCTCCAG CCTGGAGGCTTACTGCCACATCCGGGGCTTCTAGGGCCCTAGCCACCGCCCTGAGGGTGGGGACTTGGTG GCATTTGCTCTTGGACCCACCAGTCTCTCTACCCAGACTCAGCCTGGGCGCTCCCTAGGCTCTTCCTCCT CAGCCTTCTTCCTGGGATCAGCCTCCCTTTCCCCCTGGAATCCCATCCTTTGCCCTCCCTTCTCAGCTGC ATCCCCTTCAGCCCATCCTTTGTGAGGTAAACCCGAGTCCCCTGGCCAGACACTACTTCTCGGTCTTTCT GGGCACCGAGCCTGATTCTGTCTTCTCGTGTCCCTCCCTCAAGCCACGAACTTCCACCTGTGCGCCCAGG TCTTAGAACATCTCCCTAGGTACCTCAGAGGGAGGCTGTGCCATCCCAGGACGCCATCCATCTCTGCCCT TAACCACCCCAACCCTCAGGGAGCTCCCTTGCAGTCCCCAGGGAAAGGAATAGGGGTTTGTGCGGGGAGC AGGGAGAAAGGCACGCACCTTCCCTGATTTATCCACTCAGAGGCTTGGAGATGGAGGAGGGACGTTTGGA GTATCTGTCCCCCAGGCTTAGCCAGAGGAGGCACATCTTGAACCCACTACTTCTGACATTCCAGCGCCCT ACTCACCCTCCACTACCTCTGAGAGCCTAGCCACGCCTTGGAGGGAGGAGCCTGTGTGTGTATATAGTGT GTTTGGGGAGGGGGGACACGGGAGGGTGCATGTCTTGGGGAAAGGGGCGTTGACAGACTTTCCCTTCTGA GAGGGCAGCAGGACTCACTCAGCCTGAGAACCAGCTTAGTGGATGAGACTGAGACTCAAAGGGAGCCCAC CTGACCTCCCCTGACAGTATTCTAGAAGGGTTAACGAAAGTACTCTAGTCTAGAAGGTTTATTTTGCTCT CAGTGCCAGCCAATCTGGGCAGGACCCTCGAAGAGGAGACCGAGGGTCCCAGAGGACCAATGCTACAAGC CAGCAAATGCTGCCACATCTCTGCCTGTTGGGGGGCGGGGGTGGAGGGGAGGGTGGGAGGGGGGCTGGGT GGGCATTTTTAACTTTGCAGGCCATACATCTGTTGGTAGGCCACCTGCATTTTCTTACTGTTGATGTCTC CTGCCCCAAAAAAGACATCCTTGGGGAACGGGGAGTGCTGCCCACTCCTTGCGACCTTAGGTGACCCTGC CACCCTCACAGCCTTCTGCTTTCCCTAAGTTATTATTTTTGCATTTTCTTGTCCATTTGTGCATCAGACC CATTACCCACGGCCCTTCTCACCCCTTGCTCATCAGCATCACTTGATGTCCCTTCTCTGTGGTTTCTGTA AAAAACTGCCATAAAACTTTGAAATTCTGCCTGAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: BC058704
• Insert Size: 2766 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC058704, AAH58704
• RefSeq Size: 4252 bp
• RefSeq ORF: 2766 bp
• Locus ID: 110891
• Cytogenetics: 7 8.75 cM
• Gene Summary: Mediates the electrogenic exchange of Ca(2+) against Na(+) ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca(2+) levels and Ca(2+)-dependent cellular processes. Contributes to cellular Ca(2+) homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca(2+) levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory (PubMed:12818181). Plays a role in regulating urinary Ca(2+) and Na(+) excretion (PubMed:25498502).[UniProtKB/Swiss-Prot Function]