Dact2 (NM_172826) Mouse Untagged Clone

CAT#: MC205939

Dact2 (untagged) - Mouse dapper homolog 2, antagonist of beta-catenin (xenopus) (Dact2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dact2
• Synonyms: 2900084M21Rik; A630024E20; dapper2; Dpr2; Frd2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058740
  CGCGCGGCGCGGCGGTTGAGCGTCCGGGAGATGTGGGCACCGAGCGGCCAGGGGCCCGCGGGTTGGGACC GCCGCAGGGTGGGCGCGCGACTACGAGCCGCACTGGCCGGGCTGCAGGAGCTTCAGGGGCTGCGAGCCAC GCAGCAAGCACGCGTGCGGGGAGCTCTGGGCCTGCACCCTGCGCCAGGGCCCCGCGGCCAGGAGCTGCGT CTGGAGGCGGCGCTGACCGCGCTACGGGAGCAGCTGTCACGGCTAAGGAGACAGGATGCTGGCCTGAAGA CACACTTGGACCAGCTGGATCAGCAGATAAGTGAACTACAGCTGGATGTGAGCAGGTCTTCTTGCGAGGC CTTGGATAGTGACAGCAGACCCAGCTCAGGTTTCTATGAGCTGAGCGATGCTGGTTCCTGTTCTCTGTCC ACCTCCTGCGCATCTGTTTGCAGCGACCGTCTATCCCCCTCCCTGGGTAGCTGGCTGCCTGTGTTCCAGC CCTCCAAGTCCAGGTCTGGCATCGGGGACTGGCGACCACGCTCTGCTGATGAGACCACTGTCCCTGCATG GAGCCCACAGCTCACAGAAGATAGCAGGCTCCTGCATGGTGCAGAGGGCACAGGCCGGCTGACGGGCATG TTCCGGCCCAGACCAGTATCTACAGGTGATCTCGAAAGAGTCCTTCCAGCTGACGTGGGGCTCCAGAGAG CTGGTACTGATGCTGCACATCTCCTGGGCCAGGGGATAGAGATCCCAGCCCACGCCCTGGACCCCACGTA CCAGCGTGACCTGGTGGCCAGGGGAGGCCAGGAGGTGTACCCATATCCCAGCCCCCTCCATGCGGTGGCC CTGCAGAGTCCCCTCTTCGCTCTGCCCAAAGAAGCCCCGTGTTTTGACATCTGCTCACCTCCCCAGGAGC CTCCTCTGGTCCCTGTTGATGAGAACAGGACTCAACCTGAGCCGATCCGTGAGCTGGGCTCAGCCGAAGC CTACATCCACAGGCTGTTGCATCTGCGGGGCCAAGAGCTCCCCCTGAGAGATGTGGGGCAGGAGCAGGGA GGTGACACAGCTGCTTTTCCACCGAAGCCCTGTGGCCAGAGGTCGGAGAGCACATGTCAGCTGGAGAAGC AGGCCTGTGGAGCTGACAGGGGAGGACTGAAACTAGGTAGGGGTGCTGCCAAGGACAGCCTCAAGCAACA TGGGCCTGTGTCCCTTGTGGGTGCTGAGCCCCTCAGCAGCCCCCTAAAGGAAGAAACCATTCCTTGGAAT CCCTGTGTCCATGGAGACAATACTGTTGGTTCCTCACCCTGCTCCCAGGCCCAACAGCCTCTTAATGACT GTGGCCAAGGACCAGTCCTGTCACCATCCAGGGTGTTGGGCACTGAGAGCCCACCTCTGGCCCCGGAGCC CTTTGCCTATACATCCTGCACCACTGGTGAAACCTCTCCCGTGAAGCTGAGGATGGGCTTTTCCCAAAAC AAGGCCGTGAAGGTCAGAAGAAGAGTTAGTGAGAAAGTCCCGAGGCTAGGGAAGCAGCTCCCTCCACAAC CAGAGAGGCAGCGGGTCACAGAGCGGGACCCCTCCAGGCCCCATCAGGGAGGTCTCAGCAGGAGGCCCAC ACTGGCCCGGGAGCCTCCTGGACGCTCCTGCTCTGAGTCCACCCTCTACCCCGTGCCCTTCCTTGTCCCC GTAGTGGTGGCCCAGAGGGAAAGTTACCCAACGTCACCCCAAGCGTTCTTCCCAATGGAGGCAGCTCTCC TCAGCTCAGCAGCCAGGCGGAAGCAGCGCAGGTGGCAGTCCACCATGGAGATCTCAGCCAAAGCCGGTTC AGTCAGCCAACCTGGGCCCAGCATGGGGCTCCCTAGGTCCCCAGCCAAGAGAGGAAGTGGTCCCAGGGCC CAGAGTAGGCCCACACTTGCCCGTCAGGATGCCTGTGCGAGGTGTGAGTCGGACCCCTCGGAGCACTCTG CAGACTGCACCTCACTCTACCACTCCACCATTGCCGAGACCAGCGAGGACGAGGAGGCGAGTGACCACAC TGCCAACCGCTTTGGGGACGAGTCCAGCAGCAACGATTCAGAAGGGTGTTTCCGGGGCAGCCGCCGTCGC CTGGCAATAGGCAGTGCAGAGGCTGGGCAAGGGGGGTGGGCCTGGCCTCGGGTGCCCCCCCAGCAGCCCT CACGGGCCCCAGGAAACACCAGGCCACCCTTGCCCCCTGTGCCCAAACTGTGCCGCATCAAGGCCTCCAA GGCCCTGAAGAAGAAGATCCGAAGGTTTCAGCCAGCAGCCCTGAAGGTCATGACCATGGTGTGATGGCAG TGTTTCAGGACAAGCCTAGGACCCCAGAAGGTGCCATATGATGTGGTACCCCGTGCCATGTGATGAGCCG GGGGAGGGTGGTATCAACCTGCTATTGCGCTTAGTTTTCTCAGCCACCCTCACTGTGGTTGGGAGTCGTC TGGGGTCACATTCCCTCCAGCCATTTTCATTGCATGACCGCAGTCACAACTTTGCTCCTCACCATCCTCT GCCTGATTTGTGGGGAGAGGTCTCTAATAAGACACTTCTCCCCAGAGACATGAAAGAAACATGGCATCCT TTGCGGGCGGGGGGGGGGGGGGGGGGAGAACGGGACGACGGGGACGGACCAGATTTGCATTTAACTCCAT ATTGCAGTTGTATGAACAAACACCTACACCATGCTGGTATAGTTCCAAATAAAAGAGCCACATTTCCTTT CTCCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_172826
• Insert Size: 2274 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC058740, AAH58740
• RefSeq Size: 2800 bp
• RefSeq ORF: 2274 bp
• Locus ID: 240025
• UniProt ID: Q7TN08
• Cytogenetics: 17 A2
• Gene Summary: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling.[UniProtKB/Swiss-Prot Function]