Vps39 (NM_178851) Mouse Untagged Clone

CAT#: MC205651

Vps39 (untagged) - Mouse vacuolar protein sorting 39 (yeast) (Vps39), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Vps39
• Synonyms: A230065P22Rik; AW743070; mVam6; Vam6; Vam6P
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC007479
  CAGGGGTCCCTGGTGGAATACGAGTCTTCCCTGTTTTCGGACGGCAGGCTCCTCCCAGCAGCAGGGGCGG GACAGTGGCGGTGAAGCTCCCGCAGCCATGCATGACGCTTTCGAGCCGGTGCCGATCCTGGAAAAGCTTC CCCTGCAGATCGACTGCCTGGCTGCCTGGGAGGAATGGCTTCTTGTTGGAACCAAGCAAGGGCATCTTCT TCTCTACAGGATTCGGAAGGATGTTGGTTGTAACAGGTTTGAGGTAACACTAGAGAAGTCCAATAAGAAC TTTTCCAAAAAGATCCAGCAGATCCATGTGGTTTCCCAGTTTAAGATTCTGGTCAGCTTGTTAGAAAACA ACATTTATGTCCATGACTTACTGACATTTCAACAAATCACTACAGTCTCAAAGGCCAAGGGCGCATCACT GTTCACCTGTGACCTCCAGCACACTGAGACGGGTGAGGAGGTGTTGCGGATGTGTGTGGCAGTGAGGAAG AAGCTGCAGCTGTACTTCTGGAAGGACAGAGAATTCCACGAACTGCAGGGAGACTTTAGTGTGCCAGATG TGCCCAAGTCCATGGCATGGTGTGAAAATTCTATCTGCGTTGGTTTCAAGAGAGACTATTACCTGATCAG GGTGGATGGAAAGGGGTCCATCAAAGAGCTCTTCCCAACAGGAAAGCAGCTGGAGCCCTTAGTTGCCCCT CTGGCAGATGGAAAAGTGGCTGTGGGTCAGGATGATCTGACTGTGGTGCTTAACGAGGAAGGCATCTGCA CTCAGAAATGCGCCCTGAACTGGACAGACATCCCAGTGGCCATGGAGCACCAGCCTCCATACATTGTTGC AGTGTTGCCACGATACGTGGAGATCCGAACACTGGAACCAAGGCTTCTGGTCCAAAGCATTGAGTTGCAA AGGCCTCGCTTCATTACATCAGGGGGATCAAACATTATCTATGTGGCCAGCAATCATTTTGTTTGGAGAC TCATTCCTGTCCCCATGGCAACCCAAATCCAACAGCTTCTCCAGGACAAGCAGTTTGAATTGGCTCTGCA GCTCGCGGAGATGAAAGATGACTCAGACAGTGAAAAGCAGCAGCAGATCCATCACATTAAGAACTTGTAT GCCTTCAACCTCTTCTGCCAGAAGCGCTTTGATGAGTCCATGCAGGTCTTTGCTAAACTTGGCACAGATC CCACCCATGTGATGGGCTTGTACCCCGACCTACTGCCCACGGACTACAGGAAGCAACTGCAGTACCCCAA CCCGCTGCCCACACTCTCTGGTGCTGAACTGGAGAAGGCTCACTTAGCTCTCATTGACTACCTGACACAG AAACGGAGCCAGTTGGTAAAGAAGCTGAATGACTCGGATCACCAGTCCAGCACCTCCCCGCTCATGGAGG GCACTCCCACCATCAAGTCCAAGAAGAAGTTACTTCAGATCATTGACACCACTCTGCTCAAGTGCTACCT CCATACAAATGTGGCCCTGGTGGCTCCCTTGCTGCGCCTGGAGAACAACCACTGTCATATCGAGGAGAGT GAGCATGTGCTGAAGAAGGCTCACAAGTACAGCGAGCTGATCATCCTGTATGAGAAGAAGGGGCTCCATG AGAAAGCTCTGCAGGTGCTAGTGGACCAGTCCAAGAAAGCAAACTCACCTTTGAAAGGCCACGAGAGGAC GGTGCAGTATCTGCAGCATTTAGGCACAGAAAACCTTCATCTGATTTTTTCCTACTCAGTCTGGGTGCTG AGAGACTTCCCAGAAGATGGCCTGAAGATATTCACTGAAGACCTCCCGGAGGTAGAGTCTCTGCCACGAG ATCGAGTACTCAACTTCTTGATAGAGAATTTCAAGGCTCTGGCCATTCCTTATCTGGAACACATCATCCA CGTGTGGGAGGAGACAGGCTCACAGTTCCACAATTGCCTGATCCAGCTGTACTGTGAGAAAGTGCAGAGT CTGATGAAAGACTACCTCCTGTCGCTGCCCACAGGTAAAAGTCCAGTCCCTGCTGGAGAGGAAGGAGGTG AACTGGGAGAATACCGACAGAAGCTGCTCATGTTCTTGGAGATTTCCAGCCACTATGATCCAGGCCGGCT CATCTGTGATTTTCCCTTTGATGGCCTCTTAGAAGAGCGAGCTCTCCTGTTGGGGCGCATGGGGAAGCAC GAACAAGCTCTCTTCATCTATGTCCACGTCTTGAAGGACACAAAGATGGCTAAGGAGTACTGCCACAAAC ACTACGACCAAAACAAAGAAGGCAACAAAGATGTGTATCTGTCCCTGCTTCGGATGTACCTGTCACCTCC AAGCATTCACTGCCTGGGGCCAATCAAACTGGAGCTCCTGGAGCCACAGGCCAACCTCCAGGCTGCCCTG CAAGTCCTAGAGCTGCACTACAGCAAATTAGACACCACCAAGGCAATCAACCTTCTGCCAGCAAACACTC AGATCAATGACATACGCATCTTTCTAGAAAAGGTCTTAGAAGAAAATGCACAAAAGAAACGGTTCAATCA AGTGCTTAAGAATCTTCTCCATGCGGAGTTCCTCAGGGTTCAGGAAGAGCGAATTTTACACCAGCAGGTG AAGTGCATCATCACTGAGGAGAAGGTGTGCATGGTATGCAAGAAGAAGATTGGGAACAGTGCATTTGCAA GATACCCCAATGGGGTGGTTGTGCACTACTTCTGCTCCAAAGAGGTAAACTCAGCCGACACCTGAGCCCG GCAGCCCAAGCACTCAGCAGTGGACAGCTCAGCTTTCCCAGAGAGTTGAAGGAGCAGCCACCTTGAGAAC CATGCACTGCTACCAGGGACGATGCTGGCCACCTTGCTCTCTGGAACATCTCCGAATTAACTGGACTTGT GACCTGGCATTGCCGGCTTTTTACTAGAAGAGATTAGTTATATCTTACGCTGTTATGTTGCAGACAATTC CAGGAGTTTAACCCCTGCTTGGACAGGAGGAAATGCACCGTCTTGCCTTTGTATACCAATCATCTGGACA AGGAGATTTCATCTCAAGTGTTTGTACCCATGGGGTTGTTGACTGTGAGTTTTCTATTACAATAACTACA CAGCTTCACAAGATTCCCCCAGCATGGCGGCCTGGAGAGTCCCATGGGAGCCCAGCACTAGAGCTTGCCA GCCCACTGACCGCAGGCTGTTTATACTGCCAGTGTTTTCTCCAGGAGTCTCCCTGCTTATCCCTTCCGTT TTCAGTCGCCTTTTCTTCCTCACTATTTATTTTACCCCTGGATCTCTTCCCTTGTACTGTCCACGCTTCC CCTCCCACTGTGTAGAGTGGGAGGTAGAGTAACTAATGCTTAAATGTGGCAAATGGGAGGCCCTGATGAG CAGGTGTCATGGACATTGTATGAAGGGTCTCAGGAGCTGAACTTTTCTACTAAGATGTGTAGGAGAACAC AAGTCTCTGTAGGTGTAGGCTTTGGTACCTCCCCGGGGCAGCACTGTGCAGGGTGTGTGGTCTAGGCAGG ATCTCTCTAGAAGTGCCTGCCTCGGCCACTCACCAGCTGCTTGGACAGGCTGTTGATTGGACAGGCTGTT GAGTCTTTATAGGTGAGCGCTGAGCATCTTCCTCCACTCTAGCCACTTTCTGTCCTGTTGTTTTCCTGGC CATAGTGTTCCCTGGCCTTTCTTCTGCAAGACTGGAGGATCGAGCTAGGATAGCTTGGTAAAGTATGTCT CACTGCACACAGGGAACAGCTAACCAGAAACCAATAGTGATGAGATGGCGTGCAGGTTTGTGGGGCACTG AGGAATGGCAAAGAGTAATGCAGGAGCAGCTCTGTTGAGTATGTCAGGGAGCCGGCAAGAGGTACGCAGA GCAAGAGGTACACAGCAACTTCTGGCCTTGGAGGCTACAGACACCAGGCACACACATGCACATACATATA TGCAGGCCACACACCCATACATAAAGTTTAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_178851
• Insert Size: 2628 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC007479, AAH07479
• RefSeq Size: 3964 bp
• RefSeq ORF: 2628 bp
• Locus ID: 269338
• UniProt ID: Q8R5L3
• Cytogenetics: 2 E5
• Gene Summary: May play a role in clustering and fusion of late endosomes and lysosomes (By similarity). Regulator of TGF-beta/activin signaling, inhibiting SMAD3- and activating SMAD2-dependent transcription. Acts by interfering with SMAD3/SMAD4 complex formation, this would lead to inhibition of SMAD3-dependent transcription and relieve SMAD3 inhibition of SMAD2-dependent promoters, thus increasing SMAD2-dependent transcription (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.