Mx2 (NM_013606) Mouse Untagged Clone

CAT#: MC205635

Mx2 (untagged) - Mouse myxovirus (influenza virus) resistance 2 (Mx2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mx2
• Synonyms: AI528743; Mx-2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC007127
  GCCGGGAGTGCTGAGTGTTGCACAGGATTCTGTGGAAGGATAGAGGATACCTTCTAAGGCTTCTTTGTAG ACACTGAGTACCCAACTGAGAGAAGAAATAAAAGATGGTTCTTAGCACAGAAGAAAACACAGGCGTTGAT TCAGTCAACTTACCCAGTGGAGAGACGGGCCTAGGAGAGAAAGACCAGGAGTCTGTGAACAATCTCTGCA GTCAGTATGAGGAGAAGGTGCGGCCCTGCATTGACCTCATCGACTCCCTGCGGGCTCTGGGTGTGGAGCA GGACCTGGCCCTGCCTGCCATCGCTGTCATTGGGGACCAGAGTTCAGGGAAGAGCTCTGTGCTGGAAGCA CTGTCTGGAGTGGCCCTCCCCAGAGGCAGTGGTATTGTCACCAGATGCCCTCTGGTGCTGAAATTGAGGA AGCTGAATGAGGGAGAGGAGTGGAGAGGCAAAGTCTCCTATGATGACATCGAAGTGGAGCTCTCTGATCC TTCAGAGGTGGAAGAGGCCATCAACAAGGGTCAGAACTTCATTGCTGGGGTAGGTCTGGGGATCAGTGAT AAGCTCATTAGCCTGGATGTCAGCTCCCCAAATGTCCCAGACCTGACTCTCATTGACCTGCCTGGAATTA CCAGGGTGGCTGTAGGCAACCAGCCTGCAGACATAGGACGCCAGATCAAGAGACTCATCAAGACATACAT CCAAAAACAGGAGACCATCAACCTGGTGGTGGTCCCCAGCAATGTGGACATTGCCACCACAGAGGCTCTG AGCATGGCTCAGGAGGTGGACCCTGAAGGGGATAGGACCATAGGGATCTTGACCAAGCCCGATCTGGTGG ACAGAGGTACTGAAGACAAGGTCGTGGATGTGGTGCGGAACCTGGTGTACCATCTGAAGAAGGGCTACAT GATAGTCAAGTGCAGAGGCCAGCAGGACATCCAAGAGCAGCTGAGCCTGACTGAGGCTCTTCAGAATGAG CAAATCTTCTTCAAGGAACACCCTCATTTCAGAGTTCTTCTGGAGGATGGGAAGGCCACAGTGCCCTGCC TGGCAGAGAGACTGACCGCAGAGCTCATCTCACACATCTGTAAATCTCTCCCTCTGCTAGAAAATCAAAT AAAGGAAAGTCACCAGAGTGCAAGTGAGGAGCTGCAGAAGTACGGTATGGACATACCAGAAGATGACAGT GAAAAAACTTTCTTCCTGATCGAAAAAATCAATGCTTTTAACCAGGACATCACTGCCCTAGTACAAGGGG AAGAGAATGTGGCAGAGGGAGAATGTCGCCTATTCACCAGGCTCCGAAAAGAGTTCTTGTCCTGGAGTAA GGAGATCGAAAAGAATTTCGCAAAAGGTTATGCTGTTTTATATAATGAAGTCTGGGCATTTGAAAAGCAG TATCGTGGCCGAGAATTGCCAGGGTTTGTGAATTACAAAACATTTGAGAACATTATAAGAAGACAAATCA AAACCCTGGAAGAACCAGCTATAGAAATGCTGCACACGGTCACTGAAATTGTACGAGCTGCCTTTACAAG TGTTTCTGAGAAAAATTTTTCTGAGTTTTATAACCTCCACAGAACTACCAAGTCCAAACTTGAAGACATC AGATTAGAACAAGAAAAGGAAGCAGAGATGTCGATCCGACTCCACTTCAAGATGGAACAAATTATCTACT GCCAGGACCAGATTTACAGAGGAGCCTTGCAGAAGGTCAGAGAGGAGGAAGCTGAGGAGGAGAAGAAGAC AAAGCATGGCACTTCCAGTTCCTCTCAGTCCCAAGATTTACAGACCTCATCCATGGCTGAGATCTTCCAG CATCTGAATGCCTACCGCCAGGAGGCTCACAACCGCATCTCCAGCCACGTTCCCTTGATCATCCAGTATT TCATCCTGAAAATGTTTGCTGAGCGGCTGCAGAAGGGCATGCTCCAGCTCCTGCAGGACAAGGATTCCTG CAGCTGGCTCCTGAAGGAGCAGAGTGACACAAGCGAGAAGAGGAAGTTCCTGAAGGAGAGGCTGGCAAGG CTGGCCCAGGCTCGGCGCCGGCTAGCCAAATTCCCTGGTTAAGCTGGCTCTGTCCTTCCCTGTGTTTCCT GGATTGTGATTCAGGGACAGAAGGGCTCCTGCCTTTCCTGGTAGCTATACCACCAGCCTTTATGCTCTGA TAAGTGCTAGCACTCAGATTTGAAGGAGCTTTCTGCTCACTCTGAGATGAGGAAGAGAAAGAGGCTCTCA AAGCTCAGCAAGTAGATGGGTAGAGGAAGCCACTTTGCTAATAAGACAACGGCTTCACCCTGAGTACTCT TCTTGCCCACCATTTAGCACACTGCCAGAAATAAATATTTGATGTACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_013606
• Insert Size: 1968 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC007127, AAH07127
• RefSeq Size: 2372 bp
• RefSeq ORF: 1968 bp
• Locus ID: 17858
• UniProt ID: Q9WVP9
• Cytogenetics: 16 57.51 cM
• Gene Summary: This gene encodes a member of the Mx protein family of large GTPases, and functions in the innate immunity system. Interferon alpha/beta treatment or viral infection induces expression of this protein, which subsequently accumulates in the cytoplasm and inhibits viral replication. It has been shown to confer resistance to vesicular stomatitis virus, a member of the rhabdovirus family, but not to influenza virus. This gene produces a functional protein in some feral mouse strains, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a frameshift that inactivates this gene product. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the functional protein. This variant is not expressed in the mouse reference genome strain. Sequence Note: This RefSeq record was created to represent the transcript and the full-length, functional protein that is expressed in several strains. It does not contain a one nucleotide insertion that causes a frameshift in the CDS of several strains, including the strain of the reference genome, C57BL/6J.