Wdr91 (NM_001013366) Mouse Untagged Clone

CAT#: MC205464

Wdr91 (untagged) - Mouse WD repeat domain 91 (Wdr91), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Wdr91
• Synonyms: 9530020G05Rik; AI987683; AU018665
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC055046
  GCGCGCGCAGCGATGGCGGAGGCGGTGGAGCGCACAGACGAGCTGGTCCGGGAGTACCTGCTCTTCCGTG GCTTCACGCACACACTGCGGCAGCTGGATGCGGAGATCAAGGCGGACAAAGAGAAGGGGTTCCGGGTGGA CAAGATTGTGGACCAGCTGCAACAGTTGATGCAGGTTTACGACTTGGCTGCCCTTCGGGATTATTGGAGC TACCTGGAACGCAGGCTCTTCAGCCGCTTGGAGGATATCTATCGACCTACCATCAACAAACTGAAAACCA GCCTGTTCCGCTTTTATCTTGTCTACACAATCCAGACAAACCGAAATGACAAGGCACAGGAGTTCTTTGC AAAGCAGGCCACGGAGCTCCAGAACCAGGCTGAGTGGAAGGATTGGTTTGTCCTGCCCTTCTTGCCGTCC CCAGACACCAACCCCACCTTTGCTACCTACTTTTCTCGACAATGGGCCGACACATTCATTATTTCTCTGC ACAACTTCCTGAGCGTCCTCTTTCAGTGCATGCCGGTTCCTGTGATCCTGAACTTTGATGCGGAATGCCA GAGGACCAACCAGGTCCAAGAAGAAAATGAAGTTCTGCGCCAGAAGCTTTTTGCACTGCAAGCTGAAATC CATCGACTAAAGAAGGAAGAGCAGCAGCAGGAAGAAGAAGCAGCAGCTTTGGTCCAGCATAAGCTGCCGC CTTATGTTTCCAGTATGGACCGCCTTGGGGACTCGGAGCTAGCACTGGTGTGCAGCCAGAGGCCTGCCTC CCTCTCCCAGTCTCCTCGAGTGGGGTTCCTGTCCTCACTGCTGCCTCAGAGTAAGAAGAGCCCTTCGAGG TTGTCACCTGCCCAAGGCCCCCCTCAGGCTCAGAGTTCAGCCAAGAAAGACTCCTTCAGCAGTCAGGCTA CCAAGGGAAAGGACTCAGTGCCCGGGGCCAAGGATGGGAAGAGCCTTCTGAGCGGGCCGGTCCCCGGGGA AGCCAGCTGGACACATCAGCGACAACGGCGTCTGCAGGACCACGGCAAGGAGAGGAGGGAGCTGCTCTCT ACGTCCTCCTCCCAGTCACAGTGTGCAGAGAGGAAGCCGGAAGTTAGTGGCGCAGAGGCTGAGCCCTGCC TGGAACTCCACATGGGGCCAGTAGAGGTGCTGGCCCGGGTGTCCACAGCCGGGTCTGAGGGAGACCGTCC GGAGCAGCCCTTCATAGTGCTGAGCCAAGAAGAGTATGGAGAACACCATTCATCCATCATGCACTGCAGA GTGGACTGCTCTGGTAGGAGAGTGGCCAGCTTAGACGTAGATGGGGTCATCAAGGTGTGGTCCTTCAATC CCATCATGCAAACCAAAGCGTCCTCCATTTCTAAGTCACCACTGCTCTCCCTAGAGTGGGCCACCAAGCG AGACAGGCTGCTCCTGCTGGGCAGTGGTGTGGGGACAGTGCGTCTCTATGATACAGAAGCCAAGAAGAAC CTCTGTGAGATCAACATCAATGATGACATGCCCAGAATCCTGTCTCTTGCCTGCAGCCCCAACGGGGCCT CTTTCGTCTGTTCAGCCGCAGCTCCCAGCCTCACCTCCCAGACAGACTCCTCCGCCCCGGATATCGGCAG CAAAGGCATGAACCAGGTTCCTGGCAAGCTGCTGTTGTGGGATACAAAGACCATGAAGCAGCAGCTTCAG TTCTCACTGGACCCAGAGCCCATTGCCATCAACTGCACGGCTTTCAATCACAACGGGAACCTGCTGGTCA CAGGGGCGGCTGACGGTGTCATCCGGCTCTTTGACATGCAGCAGCACGAGTGTGCTATGAGCTGGAAGGC CCACTGCGGCGAGGTCTACTCTGTGGAATTCAGCTGTGACGAGAATGCTGTGTACAGCATCGGCGAGGAC CGCAAGTTCATCCAGTGGAATATCCACAAGAGTGGCCTCAAGGTGTCTGAGTCCAACCTCCCTTCAGATG CCACCGGCCCCTTTGTCCTGTCTGGCTACAGTGGCTACAAGCAGGTTCAAGTTCCCAGAGGCCGGCTCTT CGCTTTCGACTCTGAGGGCAATTACATGCTGACGTGCTCTGCCACAGGGGGCCTCATCTACAAGCTGGGC AGTGAAGAGAAAGTTCTAGAAAATTGTCTGAGCCTGGGTGGCCACCGTGCCCCTGTGGTCACCGTGGACT GGAGCACCGCCATGGACTGTGGGACGTGCCTCACAGCCTCCATGGATGGCAAGATCAAGCTGACTACCCT CCTAGCCCATAAGCTCTGATGTCGGGCCCGGCTGACACGGCACGGGAAGCAGAACCGTCTCTGGCAGAAG AGAGATGAGACGGGGGACAGGACAGGGCTCTGGTTCTGCACTGCCAGGGTGGTGGATCTTCAGGAAAGCC CCCAAGGGGGCTCAGTCGTCCTGACGAAGCCCCTGGAGCAGGAGATGTGGAGCAGGCTGCGTGTACTCCC TGGAGACTAGAACCGTGGCTATAGCGGAGCATGCTCCAGAGCACAGGACTGATGCTAAGGAAGGAGCCAC AGTGGCCGGCGCACCCTGTTCGGTCCAAGAGGCATTGACTGTATTTTGTACATAATTGCTTATTTTTCTT ATTTAAGGGGAAAAAAAAATCAGAGCAAGGTAATGCTCTTACAGTCAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_001013366
• Insert Size: 2247 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC055046, AAH55046
• RefSeq Size: 2759 bp
• RefSeq ORF: 2247 bp
• Locus ID: 101240
• UniProt ID: Q7TMQ7
• Cytogenetics: 6 B1
• Gene Summary: Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome (By similarity). May play a role in meiosis (PubMed:27346680).[UniProtKB/Swiss-Prot Function]