Dedd (NM_011615) Mouse Untagged Clone

CAT#: MC205460

Dedd (untagged) - Mouse death effector domain-containing (Dedd), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dedd
• Synonyms: CASP8IP1; Dedpro1; DEFT; FLDED1; KE05
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC054445
  CGAGGCTGAGCCGAGAATCACTGGAGATTGCAGCTGCTGAGCAGAGATTCTGGAAAGCACTCTATTTCTG AGCCTCTAGCATGGCGGGCCTAAAGAGGCGGGCAAGCCAGGTGTGGCCCGAAGAGCGTGGGGAGCAAGAA CATGGGCTCTACAGCCTCCACCGCATGTTCGACATCGTGGGCACCCACCTAACACACAGAGATGTCCGAG TGCTTTCCTTCCTTTTTGTTGATGTTATTGATGACCATGAACGTGGACTCATCCGAAATGGACGTGACTT CTTATTGGCACTGGAGCGCCAGGGCCGCTGTGACGAGAGTAACTTTCGTCAGGTGCTGCAGCTGCTGCGC ATCATCACTCGCCATGACTTGCTGCCCTACGTTACTCTCAAGAAGAGACGCGCTGTGTGCCCTGATCTTG TAGACAAGTATCTGGAGGAAACATCAATTCGCTATGTGACCCCCAGAGCCCTCAGTGACCCAGAACCGAG GCCTCCCCAGCCCTCTAAAACAGTGCCTCCCCACTATCCTGTGGTGTGCTGCCCCACTTCGGGTTCTCAA ATGTGTAGTAAGCGGCCAGCCCGAGGGAGAACCACACTTGGGAGCCAGCGAAAACGCCGGAAGTCGGTGA CACCAGACCCGAAGGAAAAGCAGACATGTGATATCAGGCTCCGAGTTCGGGCGGAATACTGCCAGCATGA GACGGCTCTGCAAGGCAATGTCTTCTCCAATAAGCAGGACCCACTTGAGCGCCAGTTTGAGCGCTTTAAC CAGGCCAACACTATCCTCAAGTCCCGGGACCTGGGCTCCATCATCTGTGACATCAAGTTCTCTGAGCTCA CCTACCTCGACGCATTCTGGCGAGACTACATTAATGGCTCATTATTAGAGGCACTGAAAGGTGTCTTCAT CACAGACTCTCTCAAGCAAGCTGTGGGCCATGAAGCCATCAAGCTGCTGGTGAACGTGGATGAGGAGGAC TATGAGCTGGGCCGACAGAAACTCCTGAGGAACTTGATGCTGCAGGTATTACCCTGACCTTTCCCCTTCT CACCTTTCTGGGGACTGTTCGCTCCGTCACCTCTGGAGCTGACATACTGTTCTGGGGTTTGTTCTCTACC CTTTCCAACCAATCACACCGCCTTTTTTTTTTTTTTTTTTTTAAAAGGAAAAGACAAAGGAAGGTGGAAG TGGTGTCCCTGCCCTCCCTGCACCCATGTGCCTGGGCTTCCCCGTTTCCTGTTGCCACTTACCCTATTGT GTGTCTACAGCCACCTTACCACTGAGCCGTAAGACAAGTGTATAGGGACAGGGTCTCTGGAACACAGCCT TTGTAAGGGATTGAACACTGCTTTCAGGTGCATTGAGGGGTAATCAATACTTATGGCTTTATGAGGGCTC TTAAATTTTGTCTGAAAAACCAAAGGGCTGTGAGTAAAGGAGCTATGTGAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_011615
• Insert Size: 957 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC054445, AAH54445
• RefSeq Size: 1496 bp
• RefSeq ORF: 957 bp
• Locus ID: 21945
• UniProt ID: Q9Z1L3
• Cytogenetics: 1 79.34 cM
• Gene Summary: A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3 (By similarity). Inhibits DNA transcription in vitro.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) lacks an internal 5' UTR exon, as compared to variant 1.