Cnmd (NM_010701) Mouse Untagged Clone

CAT#: MC205453

Lect1 (untagged) - Mouse leukocyte cell derived chemotaxin 1 (Lect1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cnmd
• Synonyms: Bricd3; ChM-I; Chmd; Lect1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC045152
  GGAACAGTTAGGACAGTGGGATAGGGTCTTCGCGTATCTTACTTCTCCATCTTCAGCCATGACAGAGAAC TCAGACAAAGTTCCTATCACCATGGTAGGGCCTGAGGACGTTGAGTTTTGCAGTCCCCCGGCGTACACCA CCGTCACCGTGAAGCCCTCCGGGAGCCCAACACGGCTGCTCAAGGTAGGAGCTGTGGTCCTCATTTCTGG CGCGGTACTGCTGCTCTTCGGGGCCATCGGGGCCTTCTACTTCTGGAAGGGGAATGACAATCACATTTAC AATGTTCATTACAGTATGAGTATCAATGGGAAACTACAAGATGGGTCAATGGAAATAGATGCTGTGAACA ACTTGGAGACCTTTAAAATGGGAAGCGGAGCGGAAGAAGCAATTGAAGTCAACGATTTTAAAAATGGCAT CACTGGGATCCGTTTTGCTGGAGGAGAGAAGTGCTACATCAAAGCACAGGTGAAGGCTCGCATCCCTGAG GTGGGCACAGTGACCAAGCAGAGCATCTCTGAACTGGAAGGCAAGATCATGCCAGCTAACTACGAAGAGA ACTCGCTGATTTGGGTGGCCGTGGACCAGCCTGTGAAGGACAGCAGCTTCTTGAGCTCTAAAATCCTTGA ACTCTGTGGCGACCTGCCGATTTTCTGGCTTAAGCCCATGTATCCAAAAGAAATCCAGAGAGAGAGAAGA GAAGTCGTGAGAAACAGTGCTCCCTCTACCACAAGAAGACCACACAGCGAACCTCGAGGTAACGCAGGCC CTGGAAGACTGAGTAACGGAACCAGACCCAATGTTCAGGACGACGCAGAACCTTTCAACCCTGACAATCC TTACCACCAGCAGGAAGGAGAAAGCATGACATTTGACCCTAGACTGGACCATGAAGGGATCTGCTGTATA GAATGCAGGCGGAGCTACACCCACTGCCAGAAGATCTGTGAACCACTGGGAGGCTACTATCCATGGCCTT ACAATTACCAAGGATGCCGCTCGGCCTGCAGAGTCGTCATGCCATGCAGCTGGTGGGTGGCCCGCATCTT GGGCATGGTGTAAATCCAGTTCATCTATCAGGACTGCCAAGCAAGAATCGATATGAGAGTTGAGAACCAA AGAAGCATAGAGCATGTCCATGCCAAGAGACCACAAAGTATTTTATATTCAACCTGAATAATGTTATCCT AAACGCTGTTGTGCACCACTGTGTGCAAATGTGCTGAAAGGGTAGTTTAACTCTACAATTATTATCATTT TACGACTTGCTTTACCAATAAAGCCTACTGCAAGTCTTTAAAAGCTACTTTTGAAATAAATATGAAAACT TAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_010701
• Insert Size: 1005 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC045152, AAH45152
• RefSeq Size: 1347 bp
• RefSeq ORF: 1005 bp
• Locus ID: 16840
• UniProt ID: Q9Z1F6
• Cytogenetics: 14 D3
• Gene Summary: Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development (By similarity). Inhibits in vitro tube formation and mobilization of endothelial cells (By similarity). Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (2) has the same N- and C- termini, but is four amino acids shorter than isoform 1.