Nod1 (NM_172729) Mouse Untagged Clone

CAT#: MC205444

Nod1 (untagged) - Mouse nucleotide-binding oligomerization domain containing 1 (Nod1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Nod1
• Synonyms: C230079P11; Card4; F830007N14Rik; Nlrc1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC042670
  CGGACGCGTGGGTCGACCCACGCGTCCGGCCAGCTCCTGATCCCGGACCGCGAGCGGTAGCGCCCTCCCT CCCAGCTGTTGTCCCGCCCGATCCGCGACCCTAGTCCCCGGATCCCCTTGCTGAGAGTCACCGTACTCCA GGGCCAACTGAGCCAAAGTCCTGCCAACTTGGGTCAGCAATGAAAGGCAGGATCCCGGGTGGTGGCCCTG AATCCTGATTTGTCTGCCCTGCCAGCGAGACACATGTGGTCAAAGATGAATTTGAGAAAAGTAGCTGCTG GCTACTTGAACAATGGAGGAACACGGCCATCATGAGATGGAAGGCACCCCATTGGGTTGTCACTCCCACA TTAAACTGCTGAAGATCAACAGGGAACATCTGGTCACCAACATTCGGAACACTCAGTGTCTGGTGGACAA CTTGCTGGAGAATGGCTACTTCTCAGCCGAAGATGCAGAGATTGTGTGTGCCTGTCCCACCAAGCCTGAC AAGGTCCGAAAGATCCTTGACCTGGTGCAGAGCAAAGGCGAGGAGGTGTCTGAGTTCTTCCTCTACGTGC TGCAGCAGCTGGAGGATGCTTACGTGGACCTCAGGCTGTGGCTCTCAGAAATTGGCTTCTCCCCTTCCCA GCTCATTCGGACCAAAACTATCGTCAATACTGACCCAGTAAGCAGGTATACCCAACAGCTGCGACACCAA CTGGGCCGCGACTCCAAGTTCATGCTGTGCTACGCCCAGAAGGAGGACCTGCTGCTGGAGGAGACCTATA TGGACACACTCATGGAGCTGGTAGGCTTCAACAATGAAAACCTGGGCAGCCTAGGAGGCCTGGATTGCCT GCTGGACCACAGTACGGGCGTCCTCAACGAGCATGGCGAGACTGTCTTCGTGTTCGGGGACGCGGGAGTG GGCAAGTCCATGCTGCTGCAGAGGTTGCAGAGCCTCTGGGCGTCAGGCAGGTTGACCTCCACAGCCAAAT TCTTCTTCCACTTCCGCTGCCGCATGTTCAGCTGCTTCAAGGAGAGCGACATGCTGAGTCTGCAGGACCT GCTCTTCAAGCATTTCTGCTACCCGGAGCAGGACCCCGAGGAGGTGTTCTCCTTCTTGCTGCGCTTTCCC CACACAGCGCTCTTCACTTTTGACGGCCTGGATGAGCTGCACTCAGACTTCGACCTGAGCCGCGTGCCGG ATAGCTGCTGCCCCTGGGAGCCGGCTCACCCTCTGGTCCTGCTGGCTAACCTCCTAAGTGGGAGGCTGCT CAAGGGTGCCGGCAAATTGCTCACTGCTCGCACAGGCGTGGAGGTCCCCCGCCAGCTCCTGCGCAAAAAG GTGCTGCTCCGGGGCTTCTCCCCAAGTCACCTGCGCGCCTATGCCCGCCGGATGTTCCCCGAGCGCACAG CGCAGGAGCATCTGCTGCAGCAGCTGGATGCCAACCCCAACCTCTGCAGCCTGTGCGGGGTGCCGCTCTT CTGTTGGATCATCTTCCGTTGTTTCCAGCACTTCCAGACGGTCTTCGAGGGCTCCTCTTCACAGTTGCCG GACTGTGCTGTGACCCTGACCGATGTCTTTCTGCTGGTCACTGAGGTGCATCTGAACAGGCCGCAGCCCA GCAGCCTGGTGCAGCGCAACACGCGCAGCCCGGCGGAAACCCTACGTGCAGGCTGGCGCACGCTGCATGC GCTGGGAGAGGTGGCTCACCGAGGCACCGACAAGAGCCTCTTTGTGTTTGGCCAGGAGGAGGTGCAGGCG TCGAAGCTGCAGGAAGGAGATCTGCAGCTGGGCTTCCTGCGGGCTTTGCCCGATGTGGGCCCTGAGCAGG GCCAGTCTTACGAATTTTTCCACCTTACGCTCCAGGCCTTCTTCACCGCCTTCTTCCTGGTAGCAGATGA CAAAGTGAGCACCCGGGAGTTGCTGAGGTTCTTTCGAGAATGGACGTCTCCTGGAGAGGCAACAAGCTCG TCCTGCCATTCTTCCTTCTTCTCCTTCCAGTGCCTGGGCGGCAGAAGCCGGTTGGGCCCTGATCCTTTCA GGAACAAAGATCACTTCCAGTTCACCAACCTCTTCCTGTGCGGGCTACTGGCCAAAGCCCGACAGAAACT CCTTCGGCAGCTGGTGCCCAAGGCTATCCTGAGGAGGAAGCGCAAGGCCCTGTGGGCTCACCTGTTTGCT AGCCTGCGCTCCTACTTGAAGAGCCTACCTCGGGTCCAGTCTGGAGGCTTTAACCAGGTGCATGCCATGC CCACATTCCTGTGGATGCTGCGCTGCATCTATGAGACGCAGAGCCAGAAGGTGGGGCGCCTCGCCGCCAG GGGCATCAGTGCGGACTACCTCAAGCTGGCCTTTTGCAACGCTTGCTCTGCGGACTGCAGCGCCCTGTCC TTCGTCCTGCATCACTTCCACAGGCAGCTGGCCCTAGACCTGGACAACAACAACCTCAATGACTATGGCG TGCAGGAGCTGCAGCCTTGCTTTAGCCGTCTCACGGTTATCAGACTCAGCGTCAACCAGATCACCGACAC GGGGGTGAAGGTGCTATGTGAGGAACTGACCAAGTATAAGATCGTGACGTTCCTGGGTTTATACAACAAC CAGATAACTGATATCGGAGCCAGGTATGTGGCCCAAATCCTGGATGAATGCAGAGGCCTCAAGCACCTTA AACTAGGGAAAAACAGAATAACAAGTGAGGGCGGGAAGTGTGTGGCTTTGGCTGTGAAGAACAGCACCTC CATCGTTGATGTTGGGATGTGGGGTAATCAGATTGGAGACGAAGGGGCAAAGGCCTTCGCAGAGGCATTG AAGGACCACCCCAGCCTGACCACTCTCAGTCTTGCATTCAATGGCATCTCTCCGGAGGGAGGGAAGAGCC TTGCGCAGGCCCTGAAGCAGAACACCACACTGACAGTAATCTGGCTGACCAAAAATGAACTTAATGATGA GTCTGCAGAGTGCTTCGCTGAGATGCTGAGAGTGAACCAGACGCTACGGCATTTATGGCTGATCCAGAAT CGCATCACAGCCAAGGGGACAGCGCAGCTGGCGAGGGCACTGCAGAAGAACACAGCCATAACAGAGATTT GTCTCAATGGAAACTTGATTAAGCCCGAGGAGGCCAAAGTCTTCGAGAATGAGAAGAGAATCATCTGCTT CTGACGGACGCTCCTGGGCAGGATCTTTGTCCTAGGTTGCTCCTCAGTCACAGACAGCACTGTGCAGTCA GCAGGGTAGCAGGATGCTGTGCAGCGCCTGCAGCAAGGTGCCTGTCAGGAGCCCACACCTCCACAGTGCA CACCGATGTCCCCTGCTCATGCTTGGACTGGTAGCACCCGCGCCGCGGCTGAGACCCTGCAGACGCAGGG AGTCTTAGGAACCATCGTCACCACTCAAAGCCAGCAGGGCATCTTCTGTACAAAGATCTCCCTGCATATC CACTAGACGGAAGCTGAAGGAACGCAACAGCAGAGGAGGCCAACAGACGCCTGGCTGAAGGCTCCGTGGG ACCAACGGTGTCACCTTCAGAAAAGAGCTGGGAACTTGAGCAGAGCCGATGGTAACTTCTTGGGGAAAGA AGGCACCCAGTGACTGCATGGTTATTCTGAGTCCTCCTTCCTCTGCTTAGTCCCTCTCACTGTACAGGTC TGTTTCTTCCTCGCAGCTGTGGCTGCTGAAGTAGGTCCACTGTGGGGAGAGCTCATCACAGACTTTGGTT CGGTTCTGGATTCTCAGTGGTGGCAACCGAGAGTCAGACGATACCCTCTAGGTCAGTCTCAGAGGATCTC TATGCTGTGAGAGGGTTGAGGGCCCACCCAGAATTTTTTTTTTTACCAGTTTTTACTGTGCCTGCCCCAG GAGGGAGAATTACTTCCCAGCCTCCACAGCAGCAGGCATGGCTTGCCTCAATGGTCCTGAGATCCCAACA AAACTCTCTCCCTTGCCTGTGAGCAGAAAGTATCTTCATGTCCTCAGAAGTTGGAGGGTGACTGGACACA GTTAAGACTCAGAGAGCCAGCTGATAGCTCAAAGCAAAGCATGGCACATACCCACCACCATACCATGGTG CGCATGGGATGGGACAGTTGGAATGTTGCAGATAACGTGTTCTTTTGCCAGTTCATTTGTTAATAAAATA TTTAAAACGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_172729
• Insert Size: 2862 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC042670, AAH42670
• RefSeq Size: 4182 bp
• RefSeq ORF: 2862 bp
• Locus ID: 107607
• UniProt ID: Q8BHB0
• Cytogenetics: 6 B3
• Gene Summary: Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Recruits NLRP10 to the cell membrane following bacterial infection (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.