Oma1 (NM_025909) Mouse Untagged Clone

CAT#: MC205339

Oma1 (untagged) - Mouse OMA1 homolog, zinc metallopeptidase (S. cerevisiae) (Oma1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Oma1
• Synonyms: 2010001O09Rik; MPRP-1; ZMPOMA1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC016238
  AGCAAAAGAAAGATGAGCCTCCTTTATGGACTGCAGTCTACCAGGATAAATCGGTTTCTCTCTGGAGTGA ATAACCTGGCCAACAGGAGACAGTGGACCCCCCCAGCAAGCTGTCCACTGGCACCAAAGCTCCGAGCAGT AAATGCATACTGGGGACTGAACACAGTCAGTCATTGTCATTCAGTGACCTTACTGCCTAGAAACTTTCTT TTCTGTAGGACTCTCAATCACAAAAAATCAAGATGCCTCTCAAGTGCCCAAAGCAAGGAATTGGGGGTGC TTACCTACAGATGTACTGTGCGGGGTGATTCTGTTCTAAGACAAGGAGCAAGGAAAGTGGCTGGCGTTCC TGCTCTCGCGGCCTCCTGTTCTCCAAGCTGTCCTGCCGTAATAGAGGCCCGGAGTTTCCGTACATCTGCA AGGGTTCAGGCTGCCCCAGTCCCTCTCTTGCTGCTCATTCTGAAGCCAGTGCAAAAGCTCCTTGCTATCA TCGTGGGCAGGGGCATAAGGAAATGGTGGCAAGCACTTCCCCCTAACAAGAAGGAGCTATTTAAAGACAG CGTGAGGAAGAACAAGTGGCGGCTGCTTCTTGGTCTGAGTGCATTTGGACTGCTCTTTGTAGTGTTTTAT TTCACTCACCTGGAAGTGAGCCCTGTCACCGGAAGGAGTAAACTACTGTTAGTGGGCAAAGAACACTTCC GACTTCTGTCAGACCTGGAATATGAAGTATGGATGGAAGAATTTAAGAACGATCTGCTGCCTGAGAGAGA CCCCCGCTACCTGACTGTGAAAGAAATGGTTTATCATCTGACACAGTGCAATCGAGACGTCCCGGGGATC TCGGAGACCAACTGGGTGGTTCATGTGGTTGACTCCCCAGCCGTCAATGCCTTTGTGCTCCCAAATGGAC AAGTGTTTATTTTCACCGGGCTTCTGAATAGTGTGACGGACGTGCACCAGCTGTCCTTCCTCCTGGGCCA TGAGATCGCACACGCAGTCCTGGGGCACGCCGCAGAAAAGGCTAGCTTGGTTCATTTACTGGATTTCCTT GGTATGATTTTTCTCACAATGATTTGGGCCATTTGTCCCCGAGACAGCTTGGCAGTTTTGGGCCAGTGGA TACAGTCAAAGTTGCAGGAGTACATGTTTGATCGACCATACAGTAGAACATTGGAGGCCGAAGCTGACAA AGTTGGACTACAGCTGGCTGCAAAGGCATGTGCCGATGTAAGAGCTAGTTCAGTGTTTTGGCAGCAGATG GAGTTCTCAGAGAGTCTTCATGGCTATCCCAAGTTGCCAGAGTGGCTGTCGACACATCCTTCTCATGGGA ACCGAGCTGAGTACTTGGATAGACTCATACCACAGGCTCTCAAACTCCGGGAGGTCTGCAATTGCCCGCC ACTCTCTGGCCCAGACCCTCGGCTATTGTTCAGGCTTACTGTGAAGCGTTTTCTTGAAGACTCGGAGAAA GAGGACCTAAACATCACTGTCAAAAAGCAGAAAACGGATGCTCTCCCCATGCAGAAGCAGGAGCAGATAC CACTGACGTATGTCCTAGAGAAGAGAACTGCAGGCTGAACGGAAGTGGGTGAATCGTGGGCTCCATGAGC AGCACAGTGGACCTTTTCCTTATTACGCAACTTTTAAAAATGATGTTTTCAAGGAAAAAAAAAAAAGAAT GTTCAAAGGCCAAGTCACTTATATTATAGATATTATCTGGATTTTTCTAGGTTTTTATCTTTCATGAAAT ATTAATGTGTTTCCACCTATTTTAAAATACTGCCAATGAGGAAAACATCACAGAATAAATTGATATTATG CATTTCAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_025909
• Insert Size: 1566 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC016238, AAH16238
• RefSeq Size: 1841 bp
• RefSeq ORF: 1566 bp
• Locus ID: 67013
• UniProt ID: Q9D8H7
• Cytogenetics: 4 C6
• Gene Summary: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion (PubMed:22433842, PubMed:24616225, PubMed:26785494). May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.[UniProtKB/Swiss-Prot Function]