Cyp26b1 (NM_175475) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Cyp26b1 |
| Synonyms | CP26; P450RAI-2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | AscI-NotI | |
| ACCN | NM_175475 |
| Insert Size | 1539 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC059246, AAH59246 |
| RefSeq Size | 4188 bp |
| RefSeq ORF | 1539 bp |
| Locus ID | 232174 |
| UniProt ID | Q811W2 |
| Cytogenetics | 6 C3 |
| Summary | Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Involved in the specific inactivation of all-trans-retinoic acid (all-trans-RA), with a preference for the following substrates: all-trans-RA > 9-cis-RA > 13-cis-RA. Generates several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA. Essential for postnatal survival. Plays a central role in germ cell development: acts by degrading RA in the developing testis, preventing STRA8 expression, thereby leading to delay of meiosis. Required for the maintenance of the undifferentiated state of male germ cells during embryonic development in Sertoli cells, inducing arrest in G0 phase of the cell cycle and preventing meiotic entry. Plays a role in skeletal development, both at the level of patterning and in the ossification of bone and the establishment of some synovial joints.UniProtKB/Swiss-Prot Function Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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"NM_175475" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG222277 | Cyp26b1 (tGFP-tagged) - Mouse cytochrome P450 family 26 subfamily b polypeptide 1 (Cyp26b1) transcript variant 1, (10ug) | 10 ug |
$677.00
|
|
| MR222277 | Cyp26b1 (Myc-DDK-tagged) - Mouse cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), transcript variant 1 | 10 ug |
$289.00
$477.00
|
|
| MR222277L3 | Lenti ORF clone of Cyp26b1 (Myc-DDK-tagged) - Mouse cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), transcript variant 1 | 10 ug |
$777.00
|
|
| MR222277L4 | Lenti ORF clone of Cyp26b1 (mGFP-tagged) - Mouse cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), transcript variant 1 | 10 ug |
$777.00
|
|
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