Nacc1 (NM_025788) Mouse Untagged Clone

CAT#: MC205218

Nacc1 (untagged) - Mouse nucleus accumbens associated 1, BEN and BTB (POZ) domain containing (Nacc1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Nacc1
• Synonyms: 2010001H03Rik; 4930511N13Rik; Btbd14b; Nac1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC054800
  CGGCTGGGGCGGCCTGGCCCACAATGAATGGCCGCCGCGGCTACCACTGCTGCTGAGGCGGAGGCCGCGG AGGCCGCAGAGGCGGAGGCCGAGGCCGAGGCGCAGGGAGGCGCGCCCCGGGCCCAGGCCCGGCCCCAGCT GCCGCTGCGGAGCCCGCCGGGAGGCCCCGGAGCGCGGCCACAGCGCAGCTGCTGCCATGGCGCAGACCTT ACAGATGGAGATTCCAAACTTCGGCAACAGCATCCTTGAGTGCCTCAATGAGCAGCGGCTACAGGGACTA TACTGTGACGTGTCAGTAGTGGTGAAGGGCCATGCCTTCAAAGCCCACCGTGCTGTGCTGGCCGCTAGTA GCTCTTACTTCCGGGACCTCTTCAACAGCAGCCGCAGTGCTGTGGTAGAACTGCCGGCCGCTGTGCAGCC ACAGTCATTCCAGCAGATCCTCACATTTTGTTACACAGGCCGGCTGAGCATGAACATGGGAGACCAGTTT CTGCTCATCTACACAGCCGGCTTCCTGCAGATCCAGGAGATCATGGAGAAAGGCACTGAGTTCTTCCTCA AAGTTAGCTCTCCAAGTTGCGACTCCCAGGGCCTGCACCCGGAGGAGGCCCCATCCTCAGAGCCTCAGAG TCCTGTAGCGCAGACATTGGGGTGGCCAGCCTGTAGCACGCCACTGCCCCTTGTGTCACGGGTCAAGACA GAACAGGAGTTGGACTCAGTGCAATGCACACCCATGGCCAAGAGGCTGTGGGACAGCAGCCAGAAGGAGG CTGGAGGCAGTGGTGGCAACAACGGCAGCCGCAAGATGGCCAAGTTCTCCACGCCAGACCTGGCCCTTAA CCGGATGCCTCAGCCACTCTCAATGGCCACAGCTACAGCAGCAGTGGCTGTGGTTGCAGTAGGGGGATGT GTGAGTGGGCCCAGCATGTCAGAGCGGACCAGTCCAGGTACCTCCAGTGCTTACACCAGTGACAGCCCCA GCTCCTACCACAATGAAGAGGACGAAGAAGAAGATGCAGGTGAGGAGGGCACAGATGAGCAGTACCGTCA GATCTGCAATATGTATACAATGTACAGTATGTTGAACGTTGGCCAGACAGCTGAGAAGGTAGAGGCCCTT CCTGAGCAGGTGGTCCTTGAGTCCCGCAGTCGCATTCGAGTGCGGCAAGACCTGGCATCTCTCCCAGCTG AACTTATCAACCAGATTGGCAATCGTTGCCACCCAAAGCTCTACGATGAAGGTGACCCCTCAGAGAAGCT GGAGCTCGTGACAGGCACCAATGTATACATCACAAGGGCACAGCTTATGAACTGCCACGTCAGTGCAGGC ACGCGGCACAAGGTCTTGCTGCGGCGGCTTCTGGCTTCCTTCTTTGACCGGAATACACTGGCCAATAGCT GTGGCACCGGCATCCGTTCTTCCACCAATGACCCCAGACGAAAGCCACTGGACAGTCGTGTCCTCCATGC TGTCAAGTACTACTGCCAGAACTTCGCCCCCAACTTCAAGGAGAGCGAGATGAATGCCATTGCAGCTGAC ATGTGCACCAATGCCCGCCGAGTGGTACGTAAAAGCTGGCTGCCCAAGACTAAGCCGCTGCACCTGGTGG AGGGTGATAACTACAGCAGCTTCATCAGCGACACTTGCAAGATAGAACCGGACATGATGAGCATGGAACA CAGCTTCGAGACAGCCAGCCACGATGGCGAGGCTGGCCCTTCAGCTGAGGTTCTCCAGTAACATACATGT GACACCCCCTTACTGGATGTCACACTCCCCTCCTATCACACCCTCACCTATCACCTACCTGGTCACGATC TACTGTCTGTCCCTCCCCAGGACCTGTGAGGGGCTGCTCCATGCCCTCTATCCGGATGCAAGAGCTGGCT GACAAGGCCAAACCACTGTACCTAGGAGAGGGCAGTGCCTACAACAGCTTTCTCAGTGACCATGAGGAAG AGCAGAACTTGATAGGCATAGAATACAGCTTTCACACAGACAGCCCCCTCAGCGAAGGTCCTCCAATACC TGCCCAGGACCCTTCCATGGATGTCACACTCCCCTCCTGTCACATACATACCCCCACCACCTTAGTCACG AGCTACTGTCTGTCCCTCCCCAGAACCTGCAGGGGTGCTGCATGCTCCCAGCCCCTCTGCCTCCCTGTCA TCCCACACCTTTTCCCCAAAGCAAGCTGGGCTGGGTCAAGAGAGGACAGGCATCAGGTGGGATCTGTGAC CTTCCTCAACACTCACGGGGAGCCCTGGTTCCCCTTCCTCTTAGGCATTTCCCAGCACCAGGCCCGGCTA GGGGACGGGCAGGACTCAACAAGAGCCTGCCCCTCACTGTGGCTGCTTGGGACTCCACGGGCCCAGGGGT CTTCTGGACCCCTCCCACCATCCCCCAGTGCTTCCATGTCTCCAAAAGCGCCTTCCTGTCCCTCTCGTCT GTCCCTGCACCTTGGGGCTGGGGTAGGTGGGGCCAAGAGGGACTGTCTACTTTACAAACTGAGGAAACAA GCCCAAAAGGCTTAGAGAAACTCTAGAACTGACCCTCTGTGACAGCCTCCATCACGCCCCTTTTAGTCCC ACCCTGCTCTGCCTCTGTGGGCCCCCTCAGCCCAAGAGGTCATTCCAAGAGAGCAGTGCTCCTATGGGCA GGTGAGGGTCTCAGGACAGGTTTCCAGTCTGGCAGAATTTGTGGGTGTGCGTGCGTGCGTGTGTGCGTGC GTGCCTGCGTAGAGTGTTTGCTTTTAAAAACATGAAGATCAAGAGGCAGCAAGACCAGGGTCGGAACCAG GGAGCAGGCTGGGAGACTGCTGCCCTTCTCCCATCCGACCCTGGGCAGGGCTCCCAGCCCCCACCCCCTG TACATAACTTTTTGAAACATTTTTTTAGCGAATGAAATATTGAAGTATAAGATTTCCTTTTATTTTTCAA ATCAATGGGAATGTGTCTGAGGTTCCCTGGGTCCCTGGGCTGTGGAAGGCAGGATGCAGGGAAGACTGAA TGTGTGTGTGTGTGGACTGTGGGTGCATGTTTCCACAGGGGCCCAGTCCCAGTGCCCCAGGACTCCTGTG GATCCAACCAGCTTCCTCTCCCCCGGGACTAAAGTTTTAGGGTGTTCACAGGTCCCAGTTAGCTGAGCCC ACTCCTGGGGGATGAGGCAGGGCAGGGTCCGCATCCATTGTTACTGGTTTGCGGAGCTTATCTCTGGCCG CACTCCTTTCCACTCTAGCTCTCCAGGAGCAGTCTTTTGGGTGTCTTGAGTTTGACATGTGAGCACAGGG TTTCTGTTACTCCCCTCCATTAACGTCCTTTCACATCTCACTGGTTCTGTTCTAGCCCTGACCTCCCCCC CCTCCCCAACTCTGCATTCTAGCTGCCTTTTCAGAGGCAGGGGTTTGCAGGATTGGAGAAGGTGGGATGG AGCCTTTTGAGTCAGATCTGGAGACCTGTCTCCAGGCCAGCAGCACCCTCTAATCTGCCATGATCCCTCT TAACATCTGATGGTGTGAGGGTGGGGTGTTGGGTCTGACTTGGCCCCCAGTACCTTAGCCCTGGGTGGCC AAGTGGAGGGGAGTAGACATCCCTAGCTAAAGCACAAGCACCTTAGTCATACCCCCTCCCTCCGCCCTCG CCCTGGCCTGTTACCCACCTCCCCCAGCAAAGATCCCAAAGCACAATCTCCTGATAACTTGGCGAGCAGC TGAGCCTGGCCGGGATGAGCGCAGGCTGTGCTCCCTGCCCAGGTTTAGTAAGGGGGCAGTTCTGTGGGGC GGAGAGGGCTTGTAGAGTGGGCAGCAGAGCCCATTGGTTCCAAGCACCTCAGGAGGTGGCCCTGACTCCC GGGGCTTGGGTTGAGGGAAGTATAAAGCCAGGGGTGCAGGGGAGAATACTACTCACTTAGGAGAGCCAAA GACAGGGTTGTGCCTTACCTCAGGAGCCACCCCTGCACCCCTCCTCTGGCAGTCAGCTGCTTGCCCTGCC CTCCTGAGAGCTGCATGGTCCCCACCCCAAGCACCCAGGAGAGTAAAAAAGTAACCCACTTAGCAGGAAA GACAAGTAGGGGCAAACCCAGTGGCTACCCTCCCACCCATCCATGCCTCTCATGGGGACAGGCCATCACC CACTGGCCCATGTGAAGTGCCAATGCCCTCCCCACCCAGAGCCGAGCCCCCACCCTTCCCAGGCCCACAA GTGAGATTGCACATTAACTACTGTATGGAGAGGAGCGGTGTTGGGAAATGTGAACCCTGAGAGTCAGTGA TGCTGATAAGAATAAACAAGACGCCTTTGTAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_025788
• Insert Size: 1545 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC054800, AAH54800
• RefSeq Size: 4332 bp
• RefSeq ORF: 1545 bp
• Locus ID: 66830
• UniProt ID: Q7TSZ8
• Cytogenetics: 8 41.02 cM
• Gene Summary: Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. Involved in the acute behavioral and neurological responses to cocaine and amphetamines.[UniProtKB/Swiss-Prot Function]