Dmbx1 (NM_001025567) Mouse Untagged Clone

CAT#: MC205173

Dmbx1 (untagged) - Mouse diencephalon/mesencephalon homeobox 1 (Dmbx1), transcript variant 2, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Dmbx1
• Synonyms: Atx; Cdmx; Mbx; Otx3
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC050912
  CGCGGGCCAAGGAGACCAGGCGGATGCCGCCATGCAGCACTATGGGGTGAATGGCTACTCCCTGCACGCT ATGAACTCACTCAGCGCCATGTACAACCTGCACCAGCAGGCAGCCCAGCAGGCCCAGCACGCCCCCGACT ACCGGCCATCAGTGCATGCGCTTACGTTGGCTGAGCGCCTAGCTGACATCATCTTGGAGGCCCGCTATGG CTCCCAGCACCGTAAACAACGTCGGAGTCGCACGGCGTTCACGGCCCAGCAGCTTGAGGCCCTGGAGAAG ACCTTCCAAAAGACTCATTACCCAGATGTGGTGATGCGCGAGAGGCTGGCCATGTGTACCAATCTTCCTG AGGCCCGTGTACAGGTGTGGTTTAAGAACCGCAGGGCCAAGTTCCGAAAGAAGCAGCGCAGCCTGCAGAA AGAGCAGCTCCAGAAACAGAAGGAGGCCGAGGGTTCCCACGGAGAAGGCAAGGTGGAGGCCCCAGCCTCA GACACGCAGCTGGAAACAGAACAGCCTCCTGGTTTGCCCAGTGGTGATCCTCCTGCTGAACTTCAACTGA GCCTGTCGGAGCAGTCAGCCAGCGAGTCTGCCCCAGAAGATCAGCTGGACCGTGAAGAGGACTCCCGTGC CGAGGAGCCCAAAGCTGAAAAGAGCCCTGGATCTGAGAGCAAGGTGCCGGGCTGCAAGAGGGGCAGCCCT AAGGCAGATTCCCCAGGCAGCCTGGCCATAACGCCCGCAGCCCCAGGGGGCGGCCTCCTTGGTCCTTCCC ACTCCTACTCCTCATCCCCACTCAGCCTCTTCCGTCTGCAGGAGCAGTTCCGCCAGCATATGGCGGCCAC CAACAACCTGATGCACTACTCGTCTTTTGAAGTGGGCGGTCCCGCACCTGCGGCGGCTGCAGCTGCGGCG GCTGCCGTGCCCTACCTAGGGGTCAACATGGCCCCATTGAGCTCCCTACACTGCCAGTCCTATTACCAAT CCCTGTCAGCAGCTGCTGCTGCCCACCAGGGTGTGTGGGGGTCCCCATTGCTGCCGGCGCCCCCCACAGG CCTGGCACCTGCCTCCGCTGCCCTGAACAGTAAAACCACGAGCATTGAAAACCTTCGCCTCCGGGCCAAG CAGCACGCCGCATCCCTGGGACTCGATACACTCCCCAATTGACTGTCTGGCTTCTAACCCAACCATGGTC TTGGGTGTACCCCTGTCTCGGTCCCATGGTTATTCTCAGAAGGCTCTCCAAGTTCTCCTAGAACTAACTT TGAGAGCCCAGGGATGCTGGGGCCTGGAGTCCTTTCACCTTGTCTCCCTTATTCAAAGTCCCAATCCCAA GTGAAACCCACACACCCTCTGCATGGCCCTGCTTGGACCCCATGGAGGTCAAATGGGGAGGAGGGGAGCA ACTGGCTACACCCCCTCTTCAGTATTGCCTCCTCCCTCCTGCTCCCCCCCCCCCCGTTAGTAAGTTGAAG TGTGGAATGTGAGATATAAATATAAATATATAAAACTATATTTTCAGGCACTGCCTGCCCCAGGCCCCCT TTCCCTGTTCTCACATCGCCACTACCCTTGCCCCTGAGATTCACTCCAGCAGATTCTCTCTCTCTCTCTC TCTCTCTCTCTCTCTCTCTCTCTCTCTCATCCTCCTTTTTCTCCTGATCCCCCCTCCCCTGCAGCCCCAC TGCCTCTGTCTTGATCCCTGTCCCTCTACCTACCCTTGGCCTTTGGTGCTGGCTTTATTATTGTCCAGTA TTCTCAAACAGTGTTTCTTTTGGGGGTTGTAGGTTTTTTTTTTGTTTTTGTTTTTGTTGTTGTTTTTTGT TTTGGTTTTAGTCATTTTGTTTCTTCCTGTTTCTCTTCTGCTCCGCTTGGCTATCTCCTCCCTTAACCTG AACTCTCTCTAGGCAACTCTTCCATTCCATGCCCCAAGATTCATCAAAGTCCTACTTGGAGACCCAGGAG CAACAGGCAGGAGGTAGCTCTAACCCCACAGCATCTCCAGATATTAGGAGGGGCTCACAGTCACCTTTTC TTCTCTTTCTTTGCTTGGAAGTACCCGCTCCCAGATTGCAGAGGGGCAGCCGCAGTAGAACAGAGACCTC ATTGCAGGGTTCTAGAATCCCTTCTCAGTGAGTGAACCCTTATGGCTACATACGGTCTCAGGACTTGGCT TCCTGTTGCAGAGGCCGGTGTGGGAGTAGGCGCTTCTGTCTCGTTAGTCACTGGCATGGCAGGGTGTGTT CTTCTATGTCTAGGCAACCCTGCTCTGTGGACGCCCTTTCAAGCTTGCTAGGACTGTCTTGTCTGGATAA GATGATTTAGAAGATTCTGTCCATTTCCAACCACCCAGTGTTCTATGCCACAACCTTGTATGGCAGAGGC TTTAATTAAGTTTAATAATAATAACTGCAGCATAAGCACTTAGAGAAGCCCAGTTTGTAAGTTAGAACAT TACTGTTGTTTTGCTGAGGAACAGTGAGTCCTGCATACCTGAAGATCTCTGTGGATACTGCCTCTGTTTC CCAGTAAATGTAAATGGCTCCTTTTTAGGTTAGACAATCTGGATTTGATCCTATTTTTCTTGGATTCCAG TGTGAGCCTTGGGGGGGGGGGCTACTCCATTCCCCTGCCCATGGTGAGGGGTGGGCAAGATTACTTGAAT AGATTCGTGGTTATGATTCCGCAACCCTTTGGCTCGCCACAGAACCCTCAACCCCACGCCCACACAGTGG TGGCCTGGCACGACTGGCCTACAGAGCCAATAGTGCTCACCTTAGTAATGTCAGTCTGGACTGGGGTAGG AGAAGGTTTTAGCCAGTAAAAAGTGAGACAGGAAAGCATGAAAGAAAGAAACAGGAGAAGTGAGCCACGG AACACAAGGTGACTGGCCTCGTGAGAGGTGAGGCAGAGAGCCTAGGACGCAGTCTCACATTCCCACTTTC ACGCAGCAGCACCAAAGTCAGTTGAGGGTTTCTTAAGAAGGGGTATCTTCCTGGGTTCTAGAATCTGCGA ACATCAGAGGAGGAGAGACTTGGACGGGGAGATGAGAGGTTAGCAAATCCTTAGGGAGATGAGGGGGTTC TGGGTTAGGGAGGGATCAGTGATCGATCCATGGTTACCCTATTGTGGTCAGCTTCAAGAAATTATGTTTC TGTATTGTCTCATCTGGAACCAGGCGCAGGGCTGAAACTGTCTTTCTATTCCTGGGTGCAAATGACTGAT TGTCACTGGGACTTGGGATCTAACACTTCTGGGTATTACCATTTCCAGAAGCCTTCCCAACCTCCTAAAG AGCAAGGCCACCTGAGGTCATATCTGGTCATGACATGAGCCTGGTCTATCCCAGGCTTTTCTAAACTCTC TTAGATCTTTGTCATGTGTTCTCTCATGTGCTGACCCAAATCCCCAAGGCCAGAGAAGGGAGGGAAGACA CACGTGGGTTTTATCTTCATGACCATGTCTTCTTAGGAGGATTAGAGGGCACGATTCTTTGAAGAAATTG TGGGTGAGCCCACCTTCCTGACACTGCTGATGGAATCTCTCTCAGGCCTGCTGGTCACTTAGGGCAGAGA GCCCAAGGATTAAACCCTTACAAGCCCTTCTAGGAAGAGTCCTGTATGTCTCTGCTCTGTTTGAGGTCTC CTTTGCCCTGCTTCCTCATTTCCCTAGAGCATGGTTCAGGGGCCTGGGTCCCCATTTCTATGCAGAGGCT GACTGGCTGTATAGACTGCTTTTCAAACCAGCTGTTTTGTGACCACTTGTGCTTAGAGGTTGTACAAAGC CTTGGCAAAAAACAAAACACCGTGTATTGTATTTATTTATTCTGTTAGTTGATGAAGCAAAACTCAAACC TCTCACTTTCCCTCGTCCTGTCCCCTGCGTAGCACAGCATGAATCTCTGTCCTGTATATCTGTCAGTCTT TTGGCCTTACTTCCTGTGACTTTGTGACCTGTTCGTTGTCTTAATTGGCTAATAAAAGAGAACCTGGCAG CACAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_001025567
• Insert Size: 1131 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC050912, AAH50912
• RefSeq Size: 4016 bp
• RefSeq ORF: 1131 bp
• Locus ID: 140477
• UniProt ID: Q91ZK4
• Cytogenetics: 4 53.07 cM
• Gene Summary: Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development, neonatal survival, postnatal growth, and nursing ability.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, compared to variant 1. It encodes isoform b, which is shorter than isoform a.