Paox (NM_153783) Mouse Untagged Clone

CAT#: MC204884

Paox (untagged) - Mouse polyamine oxidase (exo-N4-amino) (Paox), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Paox
• Synonyms: 2410012F02Rik; AI118225; Pao
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC082783
  GGCGCCTAAGGCCAGGTCTCTGGAGGACCCTGAGCTAGCCATGGCGTTCCCTGGCCCGCGGGTGCTGGTG GTGGGCAGCGGCATCGCGGGGCTGGGCGCTGCGCAGAAGCTCTGCAGCCACCGGGCTGCTCCACACCTGC GGGTTCTGGAGGCCACCGCCAGCGCCGGGGGCCGCATCCGCTCGGAACGCTGCTTCGGTGGTGTAGTGGA GCTGGGTGCACACTGGATCCATGGGCCCTCCCAGGACAATCCTGTCTTCCAGCTGGCTGCAGAATTCGGG CTCCTGGGGGAGAAAGAATTATCGGAAGAGAACCAGCTTGTGGATACAGGAGGGCACGTGGCCCTGCCCT CCATGATCTGGTCCAGCTCTGGAACAAGTGTGAGCCTGGAGCTGATGACAGAGATGGCCCGTCTGTTCTA TGGACTGATAGAGCGGACCCGAGAATTCCTGAATGAATCTGAAACCCCAATGGCCAGTGTTGGAGAGTTC CTGAAGAAGGAGATAAGTCAGCAGGTGGCTAGCTGGACCGAGGATGATGAGGACACCAGAAAGCGCAAGC TGGCTATCCTGAATACTTTCTTCAACATAGAGTGTTGTGTGAGCGGCACCCACAGCATGGACCTGGTGGC TCTTGCACCGTTCGGGGAGTATACAGTGCTGCCTGGGCTGGATTGCATCTTGGCTGGTGGCTACCAAGGA CTTACCGACCGCATACTGGCTTCCTTGCCCAAGGATACGGTCGCTTTTGACAAGCCGGTGAAGACCATTC ACTGGAATGGGTCCTTCCAGGAAGCTGCTTTTCCAGGGGAGACCTTCCCCGTATTGGTGGAGTGTGAAGA TGGTGCCCGCCTGCCTGCACATCATGTCATTGTCACAGTGCCATTAGGTTTTCTTAAAGAACACCAAGAT ACCTTTTTTGAGCCACCACTGCCTGCCAAAAAAGCAGAAGCCATCAAAAAACTAGGCTTTGGTACCAACA ACAAAATCTTCTTGGAGTTTGAAGAGCCCTTCTGGGAGCCCGACTGCCAGTTCATCCAGGTGGTGTGGGA AGATACATCGCCCTTACAGGACACAGCCCTCTCACTCCAAGACACCTGGTTCAAGAAGCTCATTGGATTT TTGGTCCAGCCTTCTTTTGAGTCTTCACATGTGCTCTGTGGGTTTATTGCTGGGCTGGAGTCGGAGTTTA TGGAGACTCTGTCAGATGAAGAAGTGCTTCTGTCTCTAACCCAAGTACTCCGGAGAGTGACAGGAAACCC ACAATTGCCAGCAGCCAAGAGCGTACGAAGGTCTCAGTGGCACAGTGCCCCGTACACCCGAGGTTCCTAC AGCTATGTGGCTGTGGGCAGCACTGGCGATGACCTAGATCTGATGGCTCAGCCCCTCCCTGAAGATGGAA CTGGCACCCAGCTCCAGGTACTCTTTGCTGGGGAAGCCACACATCGGACATTTTATTCTACCACACATGG GGCCCTCCTGTCTGGCTGGAGAGAAGCTGATCGCCTCGTTAGTCTGTGGGACTCACAGGTGGAGCAGTCG CGGCCCAGGCTGTGAGTGCCTGCTGCTCTGCTCCACCACTCGGGCTGACCAAGCTCTGTTTGGTTTGAGG TTTGGGGATCTTACTGGTAGCTTTAATTTTGGGGAAGTGGTTTTGTTTCTCTTATCTGTTGGAGTCTGGC TTGGTCTGATCATGGATGCCCCGTTAAGTGTTGTACGCATAAAGCAGTTAACATTGAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_153783
• Insert Size: 1515 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC082783, AAH82783
• RefSeq Size: 1773 bp
• RefSeq ORF: 1515 bp
• Locus ID: 212503
• UniProt ID: Q8C0L6
• Cytogenetics: 7 F4
• Gene Summary: Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12660232, PubMed:28029774). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12660232).[UniProtKB/Swiss-Prot Function]