Sord (NM_146126) Mouse Untagged Clone

CAT#: MC204150

Sord (untagged) - Mouse sorbitol dehydrogenase (Sord), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Sord
• Synonyms: Sdh-1; Sdh1; Sodh-1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC024124
  GGCGGTTGGACGAGCAGAACCACCAGCTCCCCGCCGGGTCCAGCGGACACCTCGAAGCAAGAGAGCAACA TGGCAGCTCCAGCTAAGGGCGAGAACCTGTCCCTGGTGGTGCACGGACCTGGAGACATCCGCCTGGAGAA CTACCCAATACCTGAGCTCGGCCCAAATGATGTGTTACTAAAGATGCACTCGGTGGGGATTTGCGGCTCA GATGTTCACTACTGGGAGCATGGACGAATTGGGGACTTTGTTGTGAAAAAGCCAATGGTGCTTGGGCATG AGGCTGCTGGAACAGTCACAAAAGTAGGAGAGTTGGTGAAACATCTGAAACCAGGAGATCGGGTTGCCAT CGAGCCTGGCGTTCCCCGAGAAGTAGATGAGTACTGCAAGATTGGCCGGTACAACCTGACGCCGACTATC TTCTTCTGTGCCACGCCCCCGGATGATGGAAACCTCTGCCGATTCTACAAGCACAATGCTGACTTCTGCT ACAAGCTTCCTGACAGTGTCACTTTTGAAGAAGGGGCCCTGATTGAACCTCTCTCTGTGGGGATCTATGC CTGCCGTCGAGGTTCAGTTTCCCTGGGGAACAAGGTCCTTGTGTGTGGCGCTGGGCCAGTTGGGATGGTC ACTTTGCTTGTGGCCAAAGCAATGGGAGCTGCTCAAGTTGTGGTGACTGACCTATCCGCTTCTCGGTTGA CCAAAGCCAAGGAAGTTGGAGCAGACTTTACCATCCAGGTTGGCAAAGAGACCCCTCAGGAAATTGCCAG TAAGGTGGAAAGCCTGCTGGGAAGCAAGCCGGAGGTTACCATTGAGTGCACAGGAGCCGAGTCCTCCGTC CAGACGGGCATCTATGCCACTCACTCTGGTGGGACCTTGGTGATTGTGGGAATGGGCGCCGAGATGGTCA ATTTACCCCTGGTGCACGCAGCCATTCGGGAAGTGGATATCAAAGGCGTGTTTCGATACTGCAACACGTG GCCGATGGCAATTTCCATGCTTGCATCGAAGACGTTGAATGTAAAGCCCTTAGTTACCCACAGATTCCCC CTGGAGAAGGCAGTTGAAGCCTTTGAAACAGCCAAAAAGGGAGTGGGGCTGAAAGTTATGATCAAGTGTG ACCCCAATGACCAAAACCCCTAGATGTGAATTGATCTATGCCCTCAGCCCACTCTCTCAGCATCTGAGAG CTAAATTGCTAGAAGGGGAGGCCGTAAATGCAGAACTTTCTTTTGAATGGTAAAAATAATAAACTCATAA GCGGAGAGCCTAAGAGGAGTGGGCATGCCTTAAGGACAGAAGTAGGGACACCTTGAGGGACCTTGTAGCC AGAATGAGATGCTTATACTAAGGAAAGTCTAGCACAGAGAGTCTGGCAGATAGGTCCTGGGAACACCTTT TCTCTAGTACCTTCCTTGGGTGAGGAGACACGCATGCCTTTGTGTGTTCTACTGTGATTGCCAGAGAGTG GGGCTGACTTATGAAGAAATGGATTCATTAACATGGAAGTGGCCCCAGGGCTGAACTTTTGGTCAGCTGT TCAGAGCACAATGTTTCTCTAGTTAAGTGTCATTTATTTGAGGGGAATAAAAGGAACTTGTCTGGACCCA GACAAGGAACTGATCTGGAAGAATAAGATAAATCCCAGATGAGGTACCCTAGCTTACATTCCCCAGATGT GGAAAGTATAAGGGCACTCGGCTCTGCCCAAAGACTACCTCTGTCTCAGCTACTAAGAATTCTGTCCTTA CATTTGCAAAGTGGAGGCCCACCTTCCCAACACTGCTCATTCATGAGCAGGAGCAGTATTGGTTGCTAGG CAACCAGATTTTTTTTTTCCCAACCAAAGATCTTAAATCCTGCCTAGAGGGCCACAGGAGGGCTTGCCCC ACTCAGAGGATTAGACTCCTCTCCCAGAGTCACTCACAGGCAATTATTTCCCATTCCACTCAGTTCTGGC TACCAGAAGATGCTCCCCTCTCAGCTGGGTGAGGCTGCTGATATCTGTCGGATGGGTATCACAGCGTAAT TTCATCATAGGGCTTTTCTTTATAAGATTTGGGTCCAAATCACACCCTTTGTGATCTTAAGATAATCAAG AAATGCACAGTAACTGATGTAACTTGGGCTGCAGTCTGTAATCCACCTCTTCAGCTATAAGTAGGGGACA TGTTAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_146126
• Insert Size: 1074 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC024124, AAH24124
• RefSeq Size: 2189 bp
• RefSeq ORF: 1074 bp
• Locus ID: 20322
• UniProt ID: Q64442
• Cytogenetics: 2 60.59 cM
• Gene Summary: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols (By similarity). Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose (PubMed:6852349). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism (By similarity). May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility and protein tyrosine phosphorylation (PubMed:18799757). Has no activity on ethanol. Cannot use NADP(+) as the electron acceptor (PubMed:6852349).[UniProtKB/Swiss-Prot Function]