Senp1 (NM_144851) Mouse Untagged Clone

CAT#: MC204079

Senp1 (untagged) - Mouse SUMO1/sentrin specific peptidase 1 (Senp1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Senp1
• Synonyms: 2310046A20Rik; D15Ertd528e; E330036L07Rik; suPr-2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC023129
  GGATTCTGTGTCTTTACTAAAGCCAGTGATGTGAAGAGACCTGAAATGGATGACACAGCTGATGGGGTGA AGATGGACGCTGGGGAGGTGACCTTAGTGAACCACGGCTCCACTTTCAGAACCCACCGCCCGCCACAGTC AGGCTTTCCAGAGGAGCAGCTTCTGCTTTCTGACCAGCAGAGCTTGCCTTTCAGGCAGGGTACTTTAGAT GGATCTTTCACGTGTTCTACAAGAAGCCCAGCCTATCGTCCAGATTATCACTCAGATAACCCTTCCTCAG ACAGTTTCCTTGGCTCAGGTGACGTAAGAACCTTTGGTCAAAGTGCAAATGGACAATGGAGAAATTCCAC TCCAGCGTCAGGCTCAGCGCCACAAAAACCAAGAAATAGCCGAAGTCTTTGCCTCGAAACCCGGAAGACC TCAAGTGGATTATCAAACACCTTTGTGGGCAAGTCCAATCACCACTGCCACATGTCTGCGTATGAAAAGT CATTTCCCATTAAGCCTGCCCCAAGTCCATCCTGGAGTGGGTCATGTCGTCGGAGTCTTTTAAGCCCTAA GAAAACTCAGAGGCGACATTTCAGCACAGCAGAAGAGACAGTTCAAGAAGAAGAGAAGGAGATCTACAGA CAGCTGCTGCAGATGGTCACAGGGAAGCAGTTCTGTGTAGCGAAACCCACCACACATTTTCCGTTACGCC TGTCTCGGTGTCTTAGTTCCAATAAGAACTCTTTGAAAGACTCGCTGTTGAGAAACGGAAACTCTTGTGC ATCTCATGTCATTGGTTCTGATACGTCATCCTCTGGATCTGCCAGCATTTTAACTGCACAGGAGCAGTTG TCCCACAGTGCACATTCCCTGTCATCTGGTACCCCAGATGTTGCCTTTGGATCCAAAGACTCTGATCCTC ACCATCACCTCGCTGCACCTCATCAGCCAAATAGCTTACCAGCATCAAATACACAGTCCGAAGGGTCAGA CTCTGTGATTTTACTTAAAGTGAAAGAATCTCAGACTCCAGCTTCCAGCCCTACGTTCTTCCAGGCAGAG CTATGGATCAAAGAATTAACTAGCGTTTATGACTCTCGAGCTCGGGAAAGATTGCGCCGGATTGAAGAGC AGAAAGCATTGGCACTACAGCTTCAAAACCAGCGACTGCAGGAGCAGGAACATGCAGTACTTGACTCCGT AGAGCTTCACCTTCGTGTGCCTCTTGAAAAGGAGATTCCTGTCACAGCTGCCCAAGAAACCAGGAAAAAA AGCCACCAGCTGACTGACAGTGAAGACGAATTTCCTGAAATTACAGAGGAAATGGAAAAAGAAATAAAGA ATGTATTTCGTAACGGTAACCAGGATGAAGTCCTCAGTGAGGCATTCCGCTTGACCATTACACGCAAAGA CATTCAGACTCTAAACCATCTAAACTGGCTCAATGATGAGATCATCAATTTCTACATGAACATGCTAATG GAACGCAGTAAAGAGAAGGGGTTTCCAAGTGTACATGCGTTTAATACCTTCTTCTTCACTAAGCTAAAAA CAGCTGGTTATCAGGCAGTGAAACGCTGGACAAAGAAGGTGGATGTATTCTCCGTTGATATTCTTCTGGT GCCCATTCACTTGGGTGTGCACTGGTGTCTAGCTGTTGTAGACTTTAGAAGGAAGAGTATCACCTACTAT GATTCTATGGGTGGAATAAACAACGAGGCCTGCAGGATCCTCTTGCAATACCTAAAACAAGAAAGTGTTG ACAAGAAAAGGAAAGAGTTTGACACCAACGGCTGGCAGCTCTTCAGCAAGAAGAGCCAGGAAATCCCACA GCAGATGAATGGGAGTGACTGTGGAATGTTTGCTTGCAAATATGCTGACTGCATTACCAAAGACAGACCA ATCAACTTCACACAGCAACACATGCCATATTTCCGAAAGCGAATGGTCTGGGAGATCCTCCACCGGAAGC TCTTGTGAAGATTCTCAGTGAGCAGACACTGAGCGTGTGGGGGACCAACCTTTGCCATCGACAGCCGGAG ACCTTGGAAAGAGCTGCTCCTCCCTCCCCTGTTCTTGTACAGCCCTTGACCCTGGACCAGGCCCGGCGAG ATGCATTCACAAGCACATCTGCCTTCCCTTTTGTAGCTCAGATCCTATTTTTGCAAAGAAACTTTGGTGC TGTGAAGGGGTGAGGGAACATCCCTCCTGAAGAGACTGCCTTTCACTTCAGCTCTGCCGTCTTCTTTTCC AAGGGCTCCCGCTCACTGAGTCCCTCACTAGGAGCCCAAGAGAGCCTCGGGAAGAATCTCGGTTTCCTGT AAACCCTTGTTGCTCGGCCTTACCGAGAAGCAGGAAAGAGCATGGGCAGCAGGTAGGGGTAAAACCACCA GCATGTAGGACACACATCCCCAAGACGCAGAGTCGGCAATGGAGCTGCTTAAGTCCCTCCTCCAGGACCT TCCTATTTATGTGCCCTCCATGACCGACTGCTTCTCCTCCAAGCTGTTTCTTCACTGGTAGCGTCATCCC ATCCTAAGCACACTACACAAGCCCTGGCAGACCCTAAAGTCTCGAGCAGTCCGTTCCTTACAAGCAGGGC TGCATGTGCGAGCACGCACGTGCTGTGGGAGGGCCCCCAGAAGTACTGAGCGCAGCAGCCGGGCCCCAGC TTCAGTGCTGCCTGCTTCTGACCAAGAAGAAGGACCTTGGCGGTTAGCATCACACGCCAGAGTAGGATGA ATACAGGTCTAGGTGGTCTGTGGCTAGTTAGTTTAAATATGCTTCTAGCCTCAGAGAGTTTTATATACAT ATATGCCTATATGTGTGTATACATACATATATACACACACACACACAATGTGAAATATATATTTCACAGG GATATGTTTTTAAAAGTTAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_144851
• Insert Size: 1923 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC023129, AAH23129
• RefSeq Size: 2903 bp
• RefSeq ORF: 1923 bp
• Locus ID: 223870
• UniProt ID: P59110
• Cytogenetics: 15 54.04 cM
• Gene Summary: Protease that catalyzes two essential functions in the SUMO pathway (PubMed:15923632, PubMed:29499132). The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2 (By similarity). Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (By similarity). Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (By similarity). Deconjugates SUMO2 from MTA1 (By similarity). Deconjugates SUMO2 from MTA1 (By similarity). Deconjugates SUMO1 from METTL3 (By similarity). Desumoylates CCAR2 which decreases its interaction with SIRT1 (By similarity). Deconjugates SUMO1 from GPS2 (PubMed:29499132).[UniProtKB/Swiss-Prot Function]